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«These national guidelines are directed not just to hematologists but to all medical practitioners who might encounter
sickle cell disease patients, to inform them about hydroxyurea and
how to best offer general medical care to them,» Dr. Buchanan said.
Rod Kellems, Ph.D., study co-author and chairman of the Department of Biochemistry and Molecular Biology at the UTHealth Medical School, added, «This research provides insight into
how red blood
cells work, revealing that SphK1 - mediated elevation of S1P contributes to
sickling and promotes
disease progression and highlights potential therapeutic opportunities for
sickle cell disease.»
Scientists developing new
cell therapy methods for the treatment of disorders such as
sickle cell disease or leukemia need to consider
how their culture conditions may affect the success of their translational research.
In this exclusive interview, Adrienne Bell - Cors Shapiro, Axis Advocacy, discusses
how she believes stem
cell science is the key to curing
sickle cell disease.