Sentences with phrase «how transplanted cells»

Not exact matches

What's more, there's no telling how long stored stem cells will keep — or if the amount collected at birth would even be enough for transplant should an illness occur.

Their next experiment, Coles says, is to transplant the cells into mice with degenerating retinas to see if they restore function and later to figure out how to activate and manipulate them.

It is similar to how radiation and chemotherapy are used to «condition» patients for a bone marrow transplant, to improve engraftment of transplanted immune cells.

Future research should not only compare how embryonic stem cells, iPS cells and adult stem cells differentiate, but focus on what effects the niche in which these cells will reside, when transplanted, will have on their characteristics, including tendencies to mutate into cancer cells, notes cell and stem cell biologist Olga Genbacev at the University of California, San Francisco, (U.C.S.F.) School of Medicine.

By measuring the signal returned from the transplant locations, she was able to determine how many of the cells survived.

The mini-brain lasts about a month and it could be used to study a range of challenges in neuroscience including transplanting nerve cells that could help treat Parkinson's disease and studies on how adult nerve stem cells develop.

Coffin described how lab workers there had transplanted human prostate tumor cells into an immune - deficient lab mouse, a common procedure for procuring a colony of cells, or a human cell line, for further study.

More recently, physicians have learned how to harvest blood - forming stem cells from a donor's blood and transplant them into a patient, sidestepping the need for an operating room and a needle stick into the pelvis to extract bone marrow.

However, a new study published in Cell Reports provides clues about how the dose of transplanted bone marrow might affect patients undergoing this risky procedure, frequently used to treat cancer and blood diseases.

«The dose of transplanted bone marrow has strong and lasting effects on how HSCs specialize and coordinate their behavior,» said Rong Lu, senior author and assistant professor of stem cell biology and regenerative medicine.

They have learned how to turn on and off essential genes and how to transform embryonic stem cells into retinal cells, which can be transplanted into mice to restore vision.

To investigate how zebrafish tails take shape, Thisse's team removed some of the presumed pre-tail cells from early - stage embryos, then transplanted them into the middle of another embryo.

To tap embryonic stem cells» therapeutic potential, researchers must learn how to coax them to become a specific type of cell that can then be transplanted into the body.

Transplants of neural stem cells might be used to treat brain injuries, but how to get them to the right location?

But a deeper understanding of how Jagged regulates duct cell formation in livers could shape strategies to help fix these structures to potentially spare the 10 to 30 percent of patients that eventually need a liver transplant.»

One important line of our work has revealed mechanisms how hematopoietic stem cells can generate more myeloid cells to protect transplant recipients from lethal infections.

But they said their findings would help scientists to better understand how stem cells behaved when they were transplanted into the body.

\ n \ n «It?s still not clear how the cells sense shear stress, and researchers are trying to unravel the chain of events between mechanical force and stem cell production in order to manipulate the process to make blood stem cells for transplant.»

Additionally, this technology could provide a novel research model by which we transplant cells in vivo to study a disease and its progression from the onset, as well as directly test how effective new therapies are.»

Our physicians and scientists are working on a number of initiatives, including collecting blood and bone marrow from patients to better understand the causes of bone marrow failure syndromes and MDS; exploring possible genetic factors that guide medical care; collecting blood and bone marrow to identify specific proteins that are faulty and how these defects relate to clinical complications and outcomes; and clinical trials to improve stem cell transplants for disorders such as dyskeratosis congenita.

Goldman says we are now developing a better understanding of how cell transplants might work (but we're not ready for new trials yet).

Replacing brain cells using stem cells from embryos was tried before but didn't work well, probably because we didn't understand how to look after the cells, nurture them to become neurons and get them to make the right connections when transplanted into HD brain.

One study presented in the journal — from a group led by Patrick Singleton, PhD, assistant professor of medicine at the University of Chicago Medicine — shows how opioids already present in the body can enhance the malignant tendencies of human lung cancer cells transplanted into mice, even without the addition of morphine.

This study is exploring how to improve bone marrow transplant procedures so the body better accepts donor stem cells.