Sentences with phrase «how tumor cells»

CU docs had the opportunity to watch how tumor cells develop resistance in real time.

Dr. Gollnick's laboratory explores how tumor cells co-opt the host immune system to promote chronic inflammation that leads to increased vascularization, suppression of anti-tumor immunity and increased tumor cell proliferation and migration.

Dr. Altieri also leads a research program that studies how tumor cells evade programmed cell death and the role of mitochondria, power plant of the cells, in tumor metabolism.

Understanding how tumor cells sabotage the body's immune defenses stems from the collective work of many scientists over many years and across multiple institutions.

How tumor cells gain resistance and / or avoid these therapies and which patients may benefit from these treatments is currently unknown.

They'd be able to study how tumor cells migrate: how they look, how they interact with the blood system to find nourishment to grow and spread through the body.

Interestingly, fluid shear stress also modulates how tumor cells respond to apoptosis death signals in the bloodstream.

His efforts seek to define how tumor cells escape dormancy for growth, invasion, and metastasis, and how to best develop strategies for therapy.

The Altieri laboratory is interested in how tumor cells evade apoptosis — also known as programmed cell death — which is the process that normally causes dysfunctional cells to self - destruct.

Altieri is interested in how tumor cells evade the normal processes that cause cells with genetic faults to self - destruct.

The Altieri laboratory explores the mechanisms that underlie how tumor cells survive and proliferate in cancer.

«The technology could also greatly improve our ability to study how tumor cells change in response to treatment and could help answer important biological questions about how treatment resistance arises.»

A study led by scientists from Harvard Medical School reveals «hidden» variability in how tumor cells are affected by anticancer drugs, offering new insights on why patients with the same form of cancer can have different responses to a drug.

CU docs had the opportunity to watch how tumor cells develop resistance in real time.

The findings, which come thanks to new insights about how tumor cells communicate with their environment, may also bring physicians closer to the goal of more personalized medicine.

The RNA molecules direct which proteins the cell produces, so the RNA sequences show how tumor cells behave differently to normal cells.

That's how the tumor cells may be able to avoid the induced apoptosis,» says Zou.

With the three - year grant, Vanapalli and his collaborators Boyd Butler in the Department of Biological Sciences and Everardo Cobos at the Texas Tech University Health Sciences Center, will build microfluidic devices that mimic blood flow to study how tumor cells move inside capillaries, how they squeeze through tight spaces, whether they are subject to fragmentation and how they become stuck.

A Yale Cancer Center research team conducted a study to determine how those tumor cells manage to grow outside the lungs.

The 2016 People's Choice Award went to Emmanuelle Alaluf of the Free University of Brussels, for her video using ballet and other dance styles to show how tumor cells evade the immune system.

Scientists have uncovered how tumor cells in aggressive uterine cancer can switch disguises and spread so quickly to other parts of the body.

Not exact matches

Today his company is developing a new cancer vaccine technology that teaches immune cells how to recognize and remove tumor cells.

Baby Monitors: See the Risk Wake Up Call: Cell Phones, Children and Brain Tumors EMF Protection: Renegade Health and Mary Cordaro Nesting: How to Prepare a Health Space for Your Baby The New Cellphone Study Does Not Include Health Effects on Children

To determine how the cells switch from one type to another, they took three human uterine carcinosarcoma samples and sequenced the genomes of cells in two parts of each tumor: the carcinoma and sarcoma components.

Hingtgen's group is already testing how far their tumor - homing cells can migrate using larger animal models.

Understanding how margin length decreases from surgery to pathology — because of how the removed tissue shrinks and tumor cells invade surrounding tissues — can lead to better surgical margin planning and in turn a better prognosis, said corresponding author Milan Milovancev, a board - certified veterinary surgeon at OSU's College of Veterinary Medicine.

Their paper, which appears in Nature Communications, describes how an immune cell recruited to the tumor induces the programmed suicide, or apoptosis, of the killer T cells harnessed by many immunotherapies.

To uncover how this resistance occurs, Guo and Lu teamed with Xu, Herlyn and colleagues examined both cell lines and tumor biopsies from melanoma patients before and after either BRAF inhibitor therapy or BRAF / MEK inhibitor combination therapy.

The panels show how individual melanoma cells came together to build a tumor in just four hours.

Prostate cancer risk groups are assigned based on the prostate biopsy results, which include the Gleason score (GS)-- an indication of how aggressively the tumor cells may behave — and the prostate specific antigen (PSA) level in the patient's blood at the time of diagnosis.

The scientists conducted the research using see - through zebra fish so that they could see how the cancer cells moved and expanded from the original tumor.

Published in Molecular Neurobiology, the study led by Dr Elodie Siney under the supervision of Dr Sandrine Willaime - Morawek, Lecturer in Stem Cells and Brain Repair at the University, analysed how enzymes called ADAMs affect the movement and function of the human tumor cCells and Brain Repair at the University, analysed how enzymes called ADAMs affect the movement and function of the human tumor cellscells.

Researchers at the University of Iowa did just that, documenting in real time and in 3 - D how melanoma cells form tumors.

Still, how melanoma cells join into tumors — whether by individual cells coming together or small or large clusters of cells doing so — follows the same pattern as breast tissue cancer cells: Cables are extended to reel in other cells or clusters.

The laboratory and animal study also shows how the agent, called SapC - DOPS, targets tumor cells and blood vessels.

And how do occasional cells survive in this vulnerable state — sometimes hiding out in the brain for years — to eventually spawn new tumors?

Biology professor David Soll and his team used unique computer - assisted 3 - D reconstruction software to chronicle how both breast tissue cancer cells and melanoma cells form tumors.

Human tumor cells (red) growing in a zebrafish embryo may help doctors choose how to treat cancer patients.

Knowing this could be the key to understanding how organisms — from healthy cells to cancerous tumors — replicate and multiply for their survival.

Researchers at the Bellvitge Biomedical Research Institute of Bellvitge, the Catalan Institute of Oncology and the University Hospital of Bellvitge have participated in an international study published in the journal Cancer Cell that describes how exosomes secreted by tumor cells contain protein and microRNA molecules capable of transform neighboring cells into tumoral cells promoting tumor growth.

The Campàs lab is studying several of these questions, including how limbs are built and how mechanical changes in tumors affect the behavior of malignant cells and the growth of the tumor.

Cheung and colleagues injected tumor cells into the tail veins of mice and then later assessed how many tumors sprouted.

The researchers isolated bacteria from the tumors of pancreatic cancer patients and tested how they affect the sensitivity of pancreatic cancer cells to gemcitabine, a chemotherapy drug.

Cells suspended in a stiff matrix were more likely to work their way through the matrix to other side of a serum gradient, analogous to how metastasizing cancer cells break free from their tuCells suspended in a stiff matrix were more likely to work their way through the matrix to other side of a serum gradient, analogous to how metastasizing cancer cells break free from their tucells break free from their tumors.

«Given everything we thought we knew about MYC and LIN41 at the time, we couldn't comprehend how these genes were so beneficial in somatic cell reprogramming, but absolutely useless in tumor reprogramming.

The team also compared the animals» responses to the therapy's effects in laboratory cell samples and found that in vitro studies did not predict how well the viral therapy and immune response would fight tumor cells in vivo.

Dr. Cripe and his colleagues at The Ohio State University, the University of Pittsburgh School of Medicine and Cincinnati Children's Hospital Medical Center tested how well the oncolytic viral therapy — a cancer - killing form of the herpes simplex virus, called oHSV — infected and killed tumor cells in mice with and without a healthy immune system.

However, some human tumor cells may also be hard to infect with viral therapies, Dr. Cripe reasoned, and knowing how cells respond in those situations could also be important to improving cancer treatments.

How it spreads: Unlike normal cancers, where the disease - causing mutation is confined to one organism, devil facial tumor disease (DFTD) cells have evolved the ability to spread from devil to devil.

Among factors that might skew the results: failure of participants — especially those with tumors — to accurately recall exactly how long and often they talk on their cell phones.