Not exact matches
Aside from the feat of answering the longstanding question of
how the lymph system arises, understanding
how it
forms and develops can provide important insights into disease, from metastasis to the abnormal accumulation of lymph fluids, particularly in the wake of surgery to remove cancerous
tumors.
Although there have been great advances made in the treatment of leukemias and other cancers, little is known about
how Glioblastomas are
formed and
how these
tumors infiltrate the brain tissue.
Researchers at the University of Iowa did just that, documenting in real time and in 3 - D
how melanoma cells
form tumors.
«
How melanoma
tumors form: Team identifies drugs that halt skin cancer metastasis in lab tests.»
Biology professor David Soll and his team used unique computer - assisted 3 - D reconstruction software to chronicle
how both breast tissue cancer cells and melanoma cells
form tumors.
Dr. Cripe and his colleagues at The Ohio State University, the University of Pittsburgh School of Medicine and Cincinnati Children's Hospital Medical Center tested
how well the oncolytic viral therapy — a cancer - killing
form of the herpes simplex virus, called oHSV — infected and killed
tumor cells in mice with and without a healthy immune system.
Duke Medicine researchers have shown
how gene mutations may cause common
forms of cartilage
tumors.
Study results revealed previously unknown interplay between two key enzymes and a novel understanding of
how brain cancer
tumors form and spread, according to researchers at The University of Texas MD Anderson Cancer Center.
Pathologists classify
tumors by
how far their cells deviate from their normal
forms, while hematologists identify and count different leukocytes by sight.
«Recent successes in cancer immunotherapy — in the
form of immune checkpoint inhibitors and adoptive T cell transfer — demonstrate
how activated immune cells can eradicate
tumors, but until now we didn't fully appreciate immunosurveillance or the role of adaptive immunity in
tumor formation,» said senior author Michael Karin, PhD, Distinguished Professor of Pharmacology and Pathology at UC San Diego School of Medicine.
This is important for the basic understanding of
how these
tumors are
formed and can contribute to the development of more efficient and specific glioma therapies.
They also revealed more detail about
how prostate cancer spreads, showing that the group of cells that first spread from the prostate carry on traveling around the body,
forming more secondary
tumors.
A study led by scientists from Harvard Medical School reveals «hidden» variability in
how tumor cells are affected by anticancer drugs, offering new insights on why patients with the same
form of cancer can have different responses to a drug.
According to recent research, the most common solid
tumors (that is, cancer that occurs as clusters of cells in or on organs, rather than in liquid
form within the blood or lymphatic system) have up to 66 mutations that influence
how the cancer cells operate —
how fast they divide, whether they are susceptible to the signals that would normally cause a cell to die, when they detach from the main
tumor to colonize another organ in the body, when and where they attach blood vessels to healthy tissues.
The knowledge about
how this cancer
form arises and develops is still limited but new results from a research team led by Lene Uhrbom, Uppsala University / SciLifeLab, shows that disease progress and the malignancy are affected by the cell type from which the
tumor originates as well as the age of the patient.
Massachusetts General Hospital pathologist Bradley Bernstein has studied
how alterations to chromatin drive glioblastomas, the most common
form of brain
tumor.
Researchers led by St. Jude Children's Research Hospital scientists have worked out
how a crucial cancer - related protein, a «histone writer» called Ezh2, plays a role in suppressing as well as driving the most aggressive
form of the brain
tumor medulloblastoma.