In conclusion, the early - onset and the variable nature of the repetitive behaviour, which is affected by environmental factors such as micronutrients, neutering and maternal care, share several similar components between canine and human compulsions and supports canine TC as a model for
human OCD.
However, freezing or cessation of movement during performance of activities can also occur as part of the uncommon but well recognized manifestation of
human OCD known as «obsessional slowness» [43].
Interestingly, there are indications that vitamins and minerals have beneficial effect also in
human OCD treatment.
Human OCD belongs to the group of anxiety disorders, which includes panic disorder, social phobia, specific phobia and generalized anxiety disorder [61].
This would be analogous to
human OCD, in which symptoms and co-morbidity varies significantly, leading to the consensus view that OCD is more of a spectrum of overlapping syndromes rather than a unitary disorder [1], [14].
Human OCD has been linked to the serotonin and dopamine neurotransmitter systems and altered glutamate neurotransmission [5].
Although OCD and focal seizures can co-occur,
human OCD patients typically do not show impaired responsiveness during the compulsive behaviour [42].
Neural regions expressed in
human OCD include the orbitofrontal cortex, the dorsolateral prefrontal cortex, the anterior cingulate circuit, the basal ganglia and the thalamus [18] and also the amygdala [19].
Compulsive behaviours in dogs share clinical similarities with
human OCD.
Our study reveals several similarities between canine tail chasing and
human OCD, together with a novel finding of the effect of dietary nutrients on TC.
We found no evidence for an association with a gene previously associated with canine compulsive behaviour, motivating our ongoing genetic analysis which hopefully will reveal novel loci and pathways for TC that can be replicated in
human OCD cohorts.
Canine Compulsive Disorder (CCD) is very similar to
human OCD in that dogs are also compelled to perform repetitive behaviors which eventually take over their lives.
The results, which will be published in the next issue of Genome Biology, could introduce new paths for research into
human OCD.
Dogs suffer from naturally occurring compulsive disorders that closely model
human OCD, manifested as an excessive repetition of normal canine behaviors that only partially responds to drug therapy.
The findings should spur research on the potential role of the striatum and glutamate synapses in
human OCD, says Steven Hyman, a psychiatrist at Harvard University and former director of the National Institute of Mental Health (NIMH) in Bethesda, Maryland.
Some studies with
human OCD patients have hinted at abnormal activity in this same circuit.
I think many practices of many religions stem from
human OCD tendencies.
Not exact matches
She completed an APA accredited internship at UCLA's Semel Institute of Neuroscience and
Human Behavior within the
OCD and Intensive Anxiety Track, under the supervision of Dr. Lindsey Bergman and Dr. John Piacentini.
«This method opens a window into
OCD patients» brains to help us see how responsive they will be to treatment,» said Dr. Jamie Feusner, a clinical neuroscientist at the Semel Institute for Neuroscience and
Human Behavior and the study's senior author.
«If the canine construct is fully accepted by other
OCD researchers, this spontaneously - occurring model of the condition in
humans, right down to the biological pathways involved, could help point the way to novel and more effective treatments for such a debilitating condition,» Dodman says.
Among those is canine compulsive disorder (CCD), the counterpart to
human obsessive compulsive disorder (
OCD),» says the study's first and corresponding author Nicholas Dodman, BVMS, DACVA, DACVB, professor in clinical sciences and section head and program director of animal behavior at Cummings School of Veterinary Medicine at Tufts University.
No previously recorded study in
humans or dogs has addressed the factors that drive severity in
OCD and CCD.
Additionally, 2013 MRI research from Cummings School of Veterinary Medicine at Tufts University and McLean Imaging Center at McLean Hospital showed that the structural brain abnormalities of Doberman pinschers afflicted with canine compulsive disorder (CCD) were similar to those of
humans with
OCD.
«This is particularly significant because drugs that work on the serotonin system are the mainstay treatment for
OCD in
humans, which demonstrates further correlation between the
human and animal models,» says Dodman.
These findings are consistent with those reported in
humans with
OCD.
We sequenced exons and regulatory elements for 608 genes implicated in
OCD in
humans and two animal models, mouse and dog.
Genome Biology 2014 15: R25 Obsessive - compulsive disorder (
OCD), a severe mental disease manifested in time - consuming repetition of behaviors, affects 1 to 3 % of the
human population.
We combined data from
humans, dogs and mice to find genes linked to
OCD risk.
In
humans, scientists have identified a region called the orbitofrontal cortex that is more active in
OCD subjects.
«It was very affirming to our research because it is the brain region most heavily implicated in
OCD throughout all of the
human literature.»
Shorter SRI treatment or treatment with other antidepressant drugs that do not work in
humans with
OCD were unsuccessful in reducing the behaviors caused by the drug.
One review of 15
human studies found that supplementing with the bifidobacterium and lactobacillus strains of probiotics for 1 - 2 months can improve anxiety, depression, obsessive - compulsive disorder (
OCD), and memory to boot!
CCD is believed to be a good
human model for
OCD.
Obsessive Compulsive Disorder (
OCD) in
humans is characterized by repeating thoughts (obsessions) and activities (compulsions) that cause stress.
OCD in
humans refers to Obsessive Compulsive Disorder.
«Dogs,
Humans Affected by
OCD Have Similar Brain Abnormalities.»
For example, moves, trips to the veterinarian, introduction of a new
human or animal family member, loss of a family member or other anxiety - causing events should be carefully managed to minimize their impact on dogs with
OCD.
As repetitive behaviours are core features of autism, this finding supports the hypothesis that canine compulsive behaviours have common genetic antecedents with analogous behaviours seen in
human neuropsychiatric disorders such as autism and
OCD.
First - line treatment of
OCD in
humans includes cognitive - behavioural therapy and serotonergic medication [4].
Altogether our results add more evidence for shared etiology and mechanisms of
OCD in dogs and
humans [6], and suggest that both environmental and genetic factors affect compulsive behaviour.
Behavioural inhibition (BI), which is a
human temperament style characterized by avoidance of novel stimuli (social and non-social), withdrawal and restraint, associates with certain types of
OCD (checking, doubting, obsessing, neutralizing and hoarding)[62].
Obsessive Compulsive Disorder (
OCD) is a neuropsychiatric disorder observed both in
humans and animals.
Childhood trauma and stressful events have been associated with
OCD [6], suggesting that same environmental factors may influence the development of both dog and
human compulsive behaviours.
In fact, gonadal steroids have been suggested to play a modulatory role in animal [55] and in
human compulsions [56], where premenstruum, pregnancy and post-partum have increased risk of onset and deterioration of the
OCD [55], [57].
I have experience and expertise in treating disordered eating, depression, anxiety,
OCD, and other challenges inherent in being
human in a stressful world.