Sentences with phrase «human adult stem»

Differentiation, cell fusion, and nuclear fusion during ex vivo repair of epithelium by human adult stem cells from bone marrow stroma.

Comparison of human adult stem cells from adipose tissue and bone marrow in the treatment of experimental autoimmune encephalomyelitis.

The gradual shrinking of telomeres negatively affects the replicative capacity of human adult stem cells, the cells that restore damaged tissues and / or replenish aging organs in our bodies.

By specifically targeting the pause signal that prevents restarting DNA repeat synthesis, telomerase enzymatic function can be supercharged to better stave off telomere length reduction, with the potential to rejuvenate aging human adult stem cells.

Not exact matches

Proponents of human cloning assert that this is the only method of producing pluripotent stem cells with the same genetic make - up as adult patients.

Stem cells can be obtained licitly, without loss of human life — for example, from an adult organism or from the blood of the umbilical cord at the time of birth.

Stem cells can transform into any other human cells, so they have immense potential for generating all sorts of adult cells and thus can be used in research concerning human degenerative (and other) diseases.

Whilst acknowledging that many questions remain unanswered in the debate between those who would advocate the use of stem cells taken from human embryos, and those experimenting on stem cells drawn from tissues of the adult human body, there is a lengthy discussion of the moral status of the human embryo as being a crucial matter in this regard.

To make the HSCs, the Harvard group used human skin cells to create induced pluripotent stem cells (iPSCs), adult cells researchers genetically reprogram to an embryonic - stem - cell state, where they can grow into any kind of cell.

Former Senator Rick Santorum (R — PA) is a strong backer of adult stem - cell research, and opposed to embryonic stem - cell research because he views destruction of embryos as destruction of human life.

A group in Japan hopes to test a similar approach in humans using stem cells from reprogrammed adult cells within the next three years.

Previous research shows human induced pluripotent stem cells (hiPSCs)-- generated directly from adult cells — can express markers for a wide variety of cells, including those that secrete NP.

The investigators report that trapping virus - loaded stem cells in a gel and applying them to tumors significantly improved survival in mice with glioblastoma multiforme, the most common brain tumor in human adults and also the most difficult to treat.

Eighteen adults with severe eye disease who were among the first people to receive transplants created from human embryonic stem cells (hESCs) continue to have no apparent complications with the introduced cells after an average of nearly 2 years, according to the latest status report on their health.

The results obtained by Afsaneh Gaillard's team and that Pierre Vanderhaeghen at the Institute of Interdisciplinary Research in Human and Molecular Biology show, for the first time, using mice, that pluripotent stem cells differentiated into cortical neurons make it possible to reestablish damaged adult cortical circuits, both neuroanatomically and functionally.

«Investigators create complex kidney structures from human stem cells derived from adults: New technique offers model for studying disease, progress toward cell therapy.»

Research in the laboratory of Rebecca Wingert, the Gallagher Family Associate Professor of Adult Stem Cell Research in the Department of Biological Sciences at the University of Notre Dame, has confirmed the key role of a certain small molecule in the development of kidney structures in zebrafish, a widely used model for human kidneys.

«Until now, it was not clear whether adults» sophisticated relational processing stemmed from experience with language and human culture.

Shah next plans to rationally combine the toxin - secreting stem cells with a number of different therapeutic stem cells developed by his team to further enhance their positive results in mouse models of glioblastoma, the most common brain tumor in human adults.

One possibility is that it's just random events during development, that as a few neural stem cells in a fetus give rise to a hundred billion nerve cells in an adult human brain, a lot of stuff happens.

To perform this lifesaving work, scien - tists use adult stem cells derived from the cells of mature or recently born humans or animals.

• News from the World of Adult - Stem Cell Research • At the University of California at Los Angeles, Marc Hedrick's team used human adult fat cells extracted during liposuction to make cells resembling cartilage, bone, and muAdult - Stem Cell Research • At the University of California at Los Angeles, Marc Hedrick's team used human adult fat cells extracted during liposuction to make cells resembling cartilage, bone, and muadult fat cells extracted during liposuction to make cells resembling cartilage, bone, and muscle.

All funded projects currently use stem cells from mice, rats, or primates, or adult human stem cells.

Last month, Shinya Yamanaka at Kyoto University showed he could transform adult skin cells into cells akin to human embryonic stem cells.

Prins investigated the effect of BPA on human cells by implanting human prostate stem cells taken from deceased young - adult men into mice.

Prins took human prostate stem cells from deceased young adult male organ donors and implanted the cells into mice, where they formed human prostate tissue.

Specifically, stem cell scientists at McMaster can now directly convert adult human blood cells to both central nervous system (brain and spinal cord) neurons as well as neurons in the peripheral nervous system (rest of the body) that are responsible for pain, temperature and itch perception.

Adult organisms ranging from fruit flies to humans harbor adult stem cells, some of which renew themselves through cell division while others differentiate into the specialized cells needed to replace worn - out or damaged organs and tisAdult organisms ranging from fruit flies to humans harbor adult stem cells, some of which renew themselves through cell division while others differentiate into the specialized cells needed to replace worn - out or damaged organs and tisadult stem cells, some of which renew themselves through cell division while others differentiate into the specialized cells needed to replace worn - out or damaged organs and tissues.

While stem cells — cells that have the potential to differentiate into other types of cells — exist in adult humans, the most useful stem cells are those found in embryos, which are pluripotent, capable of becoming nearly any cell in the body.

Replacement tissue that avoids rejection by a patient's immune system is a step closer to the clinic, as researchers have created human embryonic stem cells carrying the DNA of specific adults.

The 2012 platform also repeats previous calls for expanding federal funding «for the stem - cell research that now offers the greatest hope for many afflictions — with adult stem cells, umbilical cord blood, and cells reprogrammed into pluripotent stem cells — without the destruction of embryonic human life.»

In this new study, the scientists mimicked human tissue formation by starting with stem cells genetically reprogrammed from adult skin tissue to form small chambers with beating human heart cells.

So - called induced pluripotent stem (iPS) cells, which are derived from adult human tissue, have the added advantage of producing tissues and organs genetically matched to a recipient, avoiding the problem of immune system rejection.

He used adult cells — first in mice, although the technique is now feasible in human cells — to make stem cells that can form a wide range of other cells, essentially turning their cellular clocks back to infancy so they could mature into different adults.

Studies in the last two decades revealed that telomeres and telomerase have dual functions in suppressing and facilitating tumorigenesis: In the adult human, the activity of telomerase is mostly restricted to the stem cells and is absent from the vast majority of human cells.

L: We use adult stem cells, and we use the human embryonic cell lines that the government has already approved.

Single - cell RNA - Seq analysis also helped researchers benchmark the engineered 3D liver tissues generated from stem cells against naturally occurring human fetal and adult liver cells.

Xiaowei «George» Xu, MD, PhD, associate professor of Pathology and Laboratory Medicine and Dermatology at the Perelman School of Medicine, University of Pennsylvania, and colleagues published in Nature Communications a method for converting adult cells into epithelial stem cells (EpSCs), the first time anyone has achieved this in either humans or mice.

A normally functioning adult human brain has the ability to partially replenish or repair itself through neurogenesis, the proliferation and development of adult neural progenitor / stem cells (aNPCs) into new nerve cells.

But three months after the lumican - deficient mouse eyes were injected with human adult corneal stem cells, transparency was restored.

Thus, neural derivatives of disease - specific human pluripotent stem cells constitute a relevant biological resource for exploring the impact of adult - onset HD mutations of the HTT gene on the division of neural progenitors, with potential applications in HD drug discovery targeting HTT - dynein - p150Glued complex interactions.

The process transforms the adult cells into pluripotent stem cells, which seem to share the key characteristics of embryonic stem cells but do not require the creation, use, or destruction of a human embryo.

Human epidermis has been produced in vitro for decades using adult epidermal stem cells from donors to provide cell therapy.

In this new study, the scientists mimicked human tissue formation by starting with stem cells genetically reprogrammed from adult skin tissue to small chambers with beating human heart cells.

Scientists in the lab have successfully generated neural stem cells (NCS) from human embryonic stem cells and human induced pluripotent stem cells (these are stem cells that have been reprogrammed from adult cells).

Dominant - Negative Effects of Adult - Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells - Derived Neural Cells.

«Many Americans consider it unethical and immoral to destroy human embryos for scientific research, especially when adult stems cells have a proven track record of success,» he said.

Induced pluripotent stem cells that were reprogrammed from normal adult human tissue.

Induction of stem cell gene expression in adult human fibroblasts without transgenes.

Now researchers led by the Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute have managed to induce a ground state by rewiring the genetic circuitry in human embryonic stem (ES) cells and in adult cells that have been induced into a pluripotent stStem Cell Institute have managed to induce a ground state by rewiring the genetic circuitry in human embryonic stem (ES) cells and in adult cells that have been induced into a pluripotent ststem (ES) cells and in adult cells that have been induced into a pluripotent state.