Sentences with phrase «human airway cells»

They heightened the efficacy of the antimicrobials secreted by human airway cells, the body's natural immune response, as well.

In both human airway cells and mouse nasal cells, the researchers observed corrections in the targeted genes.

When Liesman infected human airway cells in the lab with this re-engineered virus, she saw infected cells ball up and puff out of the airway epithelium.

Scientists at the Johns Hopkins Kimmel Cancer Center say they have preliminary evidence in laboratory - grown, human airway cells that a condensed form of cigarette smoke triggers so - called «epigenetic» changes in the cells consistent with the earliest steps toward lung cancer development.

Not exact matches

To create the effect of tobacco smoke on cells, Vaz, Baylin and their colleagues began their studies with human bronchial cells, which line the airways of the lungs, and grew them in a laboratory.

The unaltered hemagglutinin is akin to a key that unlocks a so - called receptor molecule in cells lining the upper airways of humans and other mammals.

Now, scientists from the Perelman School of Medicine at the University of Pennsylvania reveal that the release of AMPs is partially controlled by bitter taste receptors in the upper airway on a cell previously identified in animals and only recently in humans known as solitary chemosensory cells (SCCs).

Human nasal epithelial cells, cultured on a microchip, react to air pollutants just like they would in the upper airway.

«In our human airway epithelial model system, one of the drugs destabilizes and deactivates the protein that the other drug tries to correct,» said Martina Gentzsch, PhD, an assistant professor of cell biology and physiology and senior author of the UNC Science Translational Medicine paper.

But working with human smooth muscle cells isolated and grown from the healthy parts of airway tissue surrounding excised tumors, Benjamin Kalbe and his colleagues applied a large number of odor molecules and watched two of them activate the muscle cells.

«We compared the ability of RSV and parainfluenza virus (PIV3)-- another common virus in children that causes much less severe airway disease — to infect and cause inflammatory responses in a cell culture model of human epithelial cells, which compose the lining of the lung airway.

MERS CoV (CoV stands for coronavirus) has on its surface an array of spike - shaped proteins that bind to host cells — specifically to receptor proteins called DPP4 on the surface of cells that line human airways.

Their test includes three types of human cells that are typically in a person's airway.

Human flu strains can infect both kinds of cells, but avian flu strains can bind to and infect only the ciliated kind, which are similar to cells in the airway and the gut of birds.

According to Earl Brown, professor of medicine at the University of Ottawa, the more limited ability of the avian flu virus to infect cells in the human airway thus also appears to be associated with infection of the deep areas of the lung where oxygen and carbon dioxide are exchanged.

Microscopic images show that RMC - 1 prevented FOXM1 from entering the nucleus in cultured human airway epithelial cells and in mouse allergen - sensitized respiratory airways.

The research team then tested RMC - 1 in cultured human airway epithelial cells and mouse models of asthma (via injection into the animals» peritoneal cavities).

Ripping a page from the Star Trek script, specialized cells of the barrier that lines the inside of the intestines and airways of humans have invoked a biological version of Captain Kirk's famous command «shields up» as a first defense against invading microbes.

The human airway is lined with two kinds of epithelial cells — those that possess hairlike fringes called cilia and those that don't.

The new coronavirus latches onto a protein called dipeptidyl peptidase 4, or DPP4, which decorates the surface of many cells, including some in human airways and kidneys, Bart Haagmans of Erasmus Medical Center in Rotterdam, the Netherlands, and colleagues report in the March 14 Nature.

A research team from the University of Minnesota and the Mayo Clinic took cells from the lining (epithelium) of human airways and exposed them to Alternaria.

Hypertonic Saline Primes Activation of the p53 — p21 Signaling Axis in Human Small Airway Epithelial Cells That Prevents Inflammation Induced by Pro-inflammatory Cytokines.

Building on that project, the researchers have now designed a machine that smokes cigarettes in a very human - like manner, and hooked it up to organs - on - chips lined by human lung small airway cells so the smoke interacts with these cells in a realistic way.

Here we present a novel human Airway Lung - Chip containing a fully - differentiated human mucociliary airway epithelium separated from a pulmonary microvascular endothelium by a semi-permeable membrane that allows for immune cell infiltrAirway Lung - Chip containing a fully - differentiated human mucociliary airway epithelium separated from a pulmonary microvascular endothelium by a semi-permeable membrane that allows for immune cell infiltrairway epithelium separated from a pulmonary microvascular endothelium by a semi-permeable membrane that allows for immune cell infiltration.

Additionally, we clarified the role of iNKT cells in human asthma by carefully enumerating cell numbers in airway samples from asthma and COPD patients.

Once produced, NO is freely diffusible and enters target cells and into the airway and can be detected in exhaled breath of all humans.

In this study, published in Stem Cell Reports, the researchers used both murine and human pluripotent stem cell lines with airway secretory lineage reporters, which enables their tracking, purification and profilCell Reports, the researchers used both murine and human pluripotent stem cell lines with airway secretory lineage reporters, which enables their tracking, purification and profilcell lines with airway secretory lineage reporters, which enables their tracking, purification and profiling.

Olsen CE, Liguori AE, Zong Y, Lantz RC, Burgess JL, Boitano S. Arsenic upregulates MMP - 9 and inhibits wound repair in human airway epithelial cells.