Olsen CE, Liguori AE, Zong Y, Lantz RC, Burgess JL, Boitano S. Arsenic upregulates MMP - 9 and inhibits wound repair in
human airway epithelial cells.
The research team then tested RMC - 1 in cultured
human airway epithelial cells and mouse models of asthma (via injection into the animals» peritoneal cavities).
Microscopic images show that RMC - 1 prevented FOXM1 from entering the nucleus in cultured
human airway epithelial cells and in mouse allergen - sensitized respiratory airways.
«In
our human airway epithelial model system, one of the drugs destabilizes and deactivates the protein that the other drug tries to correct,» said Martina Gentzsch, PhD, an assistant professor of cell biology and physiology and senior author of the UNC Science Translational Medicine paper.
Not exact matches
Human nasal
epithelial cells, cultured on a microchip, react to air pollutants just like they would in the upper
airway.
«We compared the ability of RSV and parainfluenza virus (PIV3)-- another common virus in children that causes much less severe
airway disease — to infect and cause inflammatory responses in a cell culture model of
human epithelial cells, which compose the lining of the lung
airway.
The
human airway is lined with two kinds of
epithelial cells — those that possess hairlike fringes called cilia and those that don't.
Hypertonic Saline Primes Activation of the p53 — p21 Signaling Axis in
Human Small
Airway Epithelial Cells That Prevents Inflammation Induced by Pro-inflammatory Cytokines.