Not exact matches
A medical doctor (of
human patients), Rothschild is often sought out these days by paleontologists for his observations about the
diseases revealed in
bones (the dinosaur kind)-- and the subsequent deductions about how these long - extinct creatures might have lived.
Human hematopoietic stem and progenitor cells (HSPCs), derived from
bone marrow, have become a primary vehicle for efforts to replace or regenerate cells destroyed by a variety of
diseases.
Not only can these social scientists correctly arrange all 206
bones that make up an adult
human skeleton, they can also determine facts about peoples» lives — age at death, sex, stature, nutritional deficiencies, levels of work stress, exposure to infectious
disease and traumas — from a careful examination of the
bones.
Subsequent transplant of millions of
human T - ALL cells into normal mice that were then treated with an anti-CXCR4 drug induced remission within two weeks, with
diseased spleen and
bone marrow tissue nearly returning to normal.
In experiments in mice and
human cells, researchers found that blocking CXCR4 — a so - called homing receptor protein molecule that helps T cells mature and attracts blood cells to the
bone marrow — halted
disease progression in
bone marrow and spleen tissue within two weeks.
Yet much of
human health and
disease relies upon proteins working outside cells, from wound healing to
bone formation.
In
humans, osteoporosis can cause serious problems such as
bone fractures, mobility limitations and spinal problems; more than 52 million Americans have or are at risk for the
disease.
Previous studies have shown the drug to be effective at spurring new
bone growth in mice and in
humans with osteoporosis, and a U-M research team believes that it may spur new growth in brittle
bone disease patients as well.
Using stem cells harvested from
human bone marrow, researchers transplanted cells into mice modeling ALS and already showing
disease symptoms.
Human skeletal biologist Simon Mays from the University of Southampton, UK, was unable to deduce the cause of death from the skeleton and he speculates that Stonehenge Man died of an infectious
disease that killed too quickly to leave a trace on
bones.
If the
bone is found to be safe and effective in
humans, it could eventually provide a readily available and cheap material for treating periodontal
disease.
Dogs diagnosed with
bone cancer often arrive at the clinic at a very advanced stage of the
disease, whereas in
humans,
bone cancer is usually detected early because people complain about the pain and have it investigated.
Molecular mechanism underlying
diseases (conformational
diseases, cystic kidney disorders, neuromuscular
diseases, inflammation, iron - related
diseases, disorders of
human reproduction, osteoporosis and
bone diseases) are being investigated by many groups with robust animal and cellular models and patients» biological samples.
In close collaboration with universities and physicians world - wide, our comprehensive investigational stem cell treatments employ well - targeted combinations of allogeneic
human umbilical cord stem cells, autologous
bone marrow stem cells, and autologous adipose stem cells for the
diseases listed below.
Led by Waisman Center and College of Agricultural and Life Sciences investigator Denise Ney and her graduate student Bridget Stroup, the study represents the first
human clinical trial to compare how different PKU - specific diets affect the
bone health of people living with the
disease.
After four months, the researchers found that the injected cells had integrated themselves in the mice's
bones as they had hoped; if the same were true in
humans, it could mean a treatment, or even a cure, for sickle cell
disease.
Dr. Lee is the Robert and Janice McNair Endowed Chair, Professor, and Chairman of the Department of Molecular and
Human Genetics, Director of the Center for Skeletal Medicine and Biology at Baylor College of Medicine, and co-Director of the Texas Medical Center
Bone Disease Program of Texas.
Several studies have surveyed
bone diseases in past
human populations and living primates and fibrous dysplasias occur in a low incidence.
A genetic screening approach to studying
bone disease has found nine new genes associated with
bone health and suggests a new way to discover genes that may be implicated in
human skeletal
diseases.
As a result, the
disease generates age - like conditions: It wipes out affected individuals»
bone marrow, predisposes them to a variety of
human cancers, and gives them splotchy skin, ratty fingernails, and prematurely gray hair.
1) Phytonutrients: * Occur naturally in fruits and vegetables * Promote the function of the immune system * Help fight off viruses as well as reduce inflammation * Associated with the treatment and / or prevention of cancer and cardiovascular
disease 2) Enzymes: * Responsible for metabolic processes that occur within a cell and are necessary for sustaining life * Assist and play a large role in digestion, energy production, blood coagulation and contraction of muscles 3) Amino Acids: * The basic building blocks of protein * Absorption of amino acids is essential for your metabolism 4) Essential Fatty Acids: * Reduce the risk of heart
disease and some forms of cancer * Improve mood * Decrease inflammation 5) Vitamins: * Essential for the normal growth and development of all
human beings * Healthy maintenance of cell tissues and organs * Help process proteins, carbohydrates and fats required for utilization 6 & 7) Macro and Trace Minerals: * Involved in electrolyte balance of body fluids * Essential for normal cellular activity * Provide hardness to
bones and teeth
«A
human heart that was slowly transforming into
bone; cancerous livers, a cancerous testicle so enlarged by its
disease that a special case had to be built to contain it; tumors sliced from noses, throats.»
Metabolic
bone disease This
disease is similar to osteoporosis is
humans where there is a lack of calcium in
bones.
Doctors in both
human and animal medicine use x-ray to find fractures of the
bone, tumor location, and foreign object identification and even to diagnose pneumonia and heart
disease.
Pets are prone to the same dental problems as
humans: gingivitis (gum inflammation), periodontitis (a
disease of the oral cavity that affects the gum,
bone and tissues around the teeth), pyorrhea (an inflammation of the gum and tooth socket that leads to loose teeth and pus); and plaque, which is a build - up of materials on the tooth enamel that can cause cavities and more serious periodontal
disease.
Dog obesity, much like
human obesity, can lead to a number of health issues including: diabetes, heat
disease and high blood pressure, respiratory ailments, digestive disorders, and orthopedic problems due to the increased stress on
bones and joints.
As in
humans, the presence of bacteria causes bad breath (bacteria stinks), and the accumulation of tartar causes irritation and inflammation to the gums around the dog's teeth (gingivitis, under the form of red, swollen gums), which in turn may lead to periodontal
disease (the loss of the connective tissue fibers, ligaments and
bone surrounding the teeth and responsible for supporting them) and eventually tooth loss due to gradual loss of supporting structure — see photo, something known as gingival recession.
This means parts not fit for
human consumption like feathers, feet, heads, ligaments, blood
bones, intestines and
diseased organs.
[v][v] In particular Hughes found the inventive concept was: «zoledronate is a useful inhibitor of
bone resorption in rats and that, as such, is suitable for use as a medicament in the treatment of
diseases in
humans associated with impairment of calcium metabolism».