Sentences with phrase «human bone marrow tissue»

In a first step towards creating artificial sperm cells, researchers have turned human bone marrow tissue into primitive sperm cells.

Not exact matches

Then, to boost the number of cells, which is another hurdle in tissue engineering, the researchers mixed the chondrocytes with human mesenchymal stem cells from bone marrow.

The researchers used «humanized mice,» which have had their immune systems replaced with human immune system cells, thymus tissue and bone marrow.

Subsequent transplant of millions of human T - ALL cells into normal mice that were then treated with an anti-CXCR4 drug induced remission within two weeks, with diseased spleen and bone marrow tissue nearly returning to normal.

In experiments in mice and human cells, researchers found that blocking CXCR4 — a so - called homing receptor protein molecule that helps T cells mature and attracts blood cells to the bone marrow — halted disease progression in bone marrow and spleen tissue within two weeks.

To test this idea, the researchers utilized two mouse models of human breast cancer metastasis and found dormant disseminated tumor cells residing upon the membrane microvasculature of lung, bone marrow and brain tissue.

The team hopes to apply this method to the nerve cells, bone marrow, and brain tissue of living animals and humans.

Prior research with cultured tissue had shown that a mix of chemicals could change bone marrow stem cells from mice to those resembling brain cells, but when a team led by neurologist Lorraine Iacovitti of Thomas Jefferson University in Philadelphia tried the same brew on human cells, the number altered was modest.

«Our group pioneered the development of cell culture technology for harvesting large numbers of stem cells from human bone marrow and human umbilical cord blood,» Dr. Yeh said, noting that stem cells from these two sources are abundant and can be guided into different types of cells using tissue engineering.

A team led by researchers at the Tufts University School of Engineering and the University of Pavia has reported development of the first three - dimensional tissue system that reproduces the complex structure and physiology of human bone marrow and successfully generates functional human platelets.

Weian Zhao, associate professor of pharmaceutical sciences, and colleagues have programmed human bone marrow stem cells to identify the unique physical properties of cancerous tissue.

David Kaplan, Ph.D., professor and Director of the NIH P41 Resource Center on Tissue Engineering, Alessandra Balduini, M.D., and their collaborators have focused on forming bone marrow models with these components and other growth factors to imitate and support the formation of functional human platelets.

Researchers funded by the National Institute of Biomedical Imaging and Bioengineering at Tufts University and their collaborators have successfully developed a 3 - dimensional (3D) tissue - engineered model of bone marrow that can produce functional human platelets outside the body (ex vivo).

Sphingosine -1-phosphate mediates proliferation maintaining the multipotency of human adult bone marrow and adipose tissue - derived stem cells (Retraction of vol 2, pg 199, 2010).

Comparison of human adult stem cells from adipose tissue and bone marrow in the treatment of experimental autoimmune encephalomyelitis.

Sphingosine -1-phosphate mediates proliferation maintaining the multipotency of human adult bone marrow and adipose tissue - derived stem cells.

Identification of common pathways mediating differentiation of bone marrow - and adipose tissue - derived human mesenchymal stem cells into three mesenchymal lineages.

Sphingosine -1-Phosphate Mediates Proliferation Maintaining the Multipotency of Human Adult Bone Marrow and Adipose Tissue - derived Stem Cells (Retracted article.

Since 2005 his group is working on the immunomodulatory activities of human mesenchymal stem cells isolated from different sources — bone marrow, adipose tissue, endometrium, decidua.