Not exact matches
In addition to shedding light on how abnormal glia can
cause schizophrenia, the study underlined how readily mouse
brains accept
human cells.
Since the first
human brain organoids were created from stem
cells in 2013, scientists have gotten them to form structures like those in the
brains of fetuses, to sprout dozens of different kinds of
brain cells, and to develop abnormalities like those
causing neurological diseases such as Timothy syndrome.
Damage to
human chromosome 9 (of the
cell's 24 pairs) where the gene that codes for E-NTPDase2 resides is known to
cause eye and
brain defects, such as microphthalmia — literally, small eyes.
In
humans, Huntington's is an inherited disease
caused by a gene encoding a toxic protein, called mutant huntingtin, which
causes brain cells to die.
Using
human fetal «mini-brains» grown in 3 - D cultures, scientists determined that a specific protein produced by the Zika virus changes the properties of neural stem
cells in the developing
brain of an infected fetus, potentially
causing microcephaly in newborns (Ki - Jun Yoon, abstract 103.06, see attached summary).
The
human body is a complex electrical network: Nerve
cells shuttle signals from the
brain, and pulses in the heart
cause its muscle
cells to expand and contract.
Working with mouse, fly and
human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a
cell's control center — the nucleus — appear to be a direct
cause of
brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.
«Zika virus may
cause microcephaly by hijacking
human immune molecule: Fetal
brain model provides first clues on how Zika virus blunts
brain development; blocking mechanism reduces
cell damage.»
In
humans, deafness is most often
caused by damage to inner ear hair
cells — so named because they sport hairlike cilia that bend when they encounter vibrations from sound waves — or by damage to the neurons that transmit that information to the
brain.
«Now, flies,
human stem
cells and autopsied
brains are all telling us the same story here, that this is a fundamental defect
causing disease,» says Rothstein.
To get to the bottom of this question, researchers in the Perelman School of Medicine at the University of Pennsylvania engineered mice in which the damage
caused by a mutant
human TDP - 43 protein could be reversed by one type of
brain immune
cell.
SAN FRANCISCO, CA — April 9, 2018 — Using
human brain cells, scientists at the Gladstone Institutes discovered the
cause of — and a potential solution for — the primary genetic risk factor for Alzheimer's disease, a gene called apoE4.
Strengthening the link between Zika virus and microcephaly, scientists at UC San Francisco have discovered that a protein the virus uses to infect skin
cells and
cause a rash is present also in stem
cells of the developing
human brain and retina.
To determine whether the Zika virus
caused this, a number of independent teams of researchers — including two in Brazil and one at the University of California, San Diego — created
brain organoids from healthy
human cells and infected some of them with the Zika virus.
It can
cause the damage of our
brain cells that is neurons which is fatal because neuron are not able to repair like other body
cells of
human body.
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