«We have shown that lncND might be an important player in
human brain expansion, which is exciting in itself,» Rani said.
Experts say this is strong evidence that ASPM could have contributed to
human brain expansion.
Jianzhi Zhang of the University of Michigan, Ann Arbor, hypothesized that ASPM might have played a key role in
human brain expansion.
Not exact matches
In a new study published in The Quarterly Review of Biology, Dr. Karen Hardy and her team bring together archaeological, anthropological, genetic, physiological and anatomical data to argue that carbohydrate consumption, particularly in the form of starch, was critical for the accelerated
expansion of the
human brain over the last million years, and coevolved both with copy number variation of the salivary amylase genes and controlled fire use for cooking.
The
expansion of the
human brain may have involved a snowball effect, in which initial mutations caused further mutations that enhanced the
brain even more
Neural stem cells called outer radial glial (oRG) cells help fuel the
expansion of the unusually big
human brain.
According to Kosik, this work not only identifies a very critical gene for
human brain development but also offers a clue about a component that likely contributed to
brain expansion in
humans.
«Considered in total, this study provides important early archaeological evidence for meat eating, hunting and scavenging behaviors - cornerstone adaptations that likely facilitated
brain expansion in
human evolution, movement of hominins out of Africa and into Eurasia, as well as important shifts in our social behavior, anatomy and physiology,» Ferraro said.
Boyden's team has also worked on the
brains of fruit flies and zebrafish, while a collaborating group is applying
expansion microscopy to
human brains.
The approach enabled a wide range of studies of
human brain development, including implicating a new class of neural stem cell recently discovered by the lab in the evolutionary
expansion of the
human brain and identifying how the mosquito - borne Zika virus may contribute to microcephaly in infants infected in utero.
Now the weird thing about sediba is, it has a very
human like pelvis but it has a tiny
brain, so obviously something, some kind of other selective force is acting on the pelvis that has nothing to do with the
expansion of
brain size that you see in our genus.
Marta received the award for her work on the gene ARHGAP11B present only in
humans and its key role in the
expansion of the neocortex and
brain evolution.
The comparison of the relative size of the prefrontal region in primate
brains is described in a paper titled «No relative
expansion of the number of prefrontal neurons in primate and
human evolution» by Herculano - Houzel and postdoctoral fellow Mariana Gabi published online this week in the Proceedings of the National Academy of Sciences early edition.
Howard Hughes Medical Institute researchers have identified a gene that appears to have played a role in the
expansion of the
human brain's cerebral cortex — a hallmark of the evolution of
humans from...
Citation: Shultz S, Maslin M (2013) Early
Human Speciation,
Brain Expansion and Dispersal Influenced by African Climate Pulses.
In addition, we wish to characterize how variations in neural stem cells behavior may account for the large
expansion of the
human brain, but also how alterations may lead to pathological
brain development.