Not exact matches
The building block electronic and protonic actual occasions are, in the case of
human beings, swept
into vastly more complex, Chinese box - like sets of containing societies within which there are social levels that can be identified with cells, others which answer to Aristotle's levels of
tissues and organs, and which finally are presided over by what Whitehead refers to as the regnant nexus, a social thread of complex temporal inheritance which, Whitehead suggests, wanders from part to part of the
brain, is the seat of conscious direction of the organism as a whole, and answers to what in Plato and Aristotle is called the soul.
The Salk team therefore took
human brain organoids that had been growing in lab dishes for 31 to 50 days and implanted them
into mouse
brains (more than 200 so far) from which they had removed a tiny bit of
tissue to make room.
To investigate, Walker Jackson of the Whitehead Institute in Boston, Massachusetts, and his colleagues created mice with a mutation associated with the
human prion disease Fatal Familial Insomnia and injected some of their
brain tissue into the
brains of mice without the mutation.
At a neuroscience meeting, two teams of researchers will report implanting
human brain organoids
into the
brains of lab rats and mice, raising the prospect that the organized, functional
human tissue could develop further within a rodent.
In the United States, these include the lack of an approved vector for transporting DNA segments for light - sensitive proteins
into human brain tissue.
To make such a detailed model, researchers took specks of
brain tissue and cut them
into slices thousands of times thinner than a
human hair.
After confirming in mouse models that cells from HER2 - positive breast cancers became resistant to anti-HER2 treatment when implanted
into the
brain but not
into other
tissues, the investigators found that HER3 is overexpressed in
brain metastases of HER2 - positive breast cancers from both mice and
human patients.
ReNeuron developed cells for
brain damage by splicing their modified c - myc
into human fetal
brain tissue obtained from a U.S. cell bank.
Anand hopes his
brain model could be incorporated
into the Microphysiological Systems program, a platform the Defense Advanced Research Projects Agency is developing by using engineered
human tissue to mimic
human physiological systems.
«This data allows classification of all
human protein - coding genes
into those coding for house - hold functions (present in all cells) and those that are
tissue - specific genes with highly specialized expression in particular organs and
tissues, such as kidney, liver,
brain, heart, pancreas.
But it does not give anything like the same level of detailed information that can be achieved by painlessly inserting electrodes
into brain tissue in animal or
human studies.
The best source for
humans is from the meat of other animals, though it can be difficult to get enough tryptophan
into the
brain, as it is the least abundant amino acid in muscle
tissue, and it has to compete with all the other more abundant aromatic amino acids for the aromatic amino acid transporter.