Sentences with phrase «human breast cancer patients»

As a next step, Guha, Avadhani and colleagues plan to extend this study to in vivo mouse models and will also investigate these mechanisms in tumor samples from human breast cancer patients.

Additional experiments using a combination of maraviroc and a drug that blocks the VEGF protein suggest that the treatment duo could be an effective way to prevent metastatic disease in human breast cancer patients, according to the researchers.

Pre-clinical studies have shown it to be effective in eliminating a number of different kinds of cancers cells, including cancer stem cells from human breast cancer patient biopsies.

Not exact matches

If further research confirms the findings in human cells, limiting the amount of asparagine cancer patients ingest could be a potential strategy to augment existing therapies and to prevent the spread of breast cancer, Knott added.

Researchers have isolated exosomes from tumors and from blood of patients with breast cancer, and from blood of mice with human tumors grown after breast implantation in mice, called ortoxenogratfs.

Horvath and Tell's research is the first reported study to compare breast cancer subtypes and gene expression patterns associated with STAT3 in the tumors of human patients.

In many human breast cancers, Numb concentration is low and this is associated with a poor prognosis for the patients.

After confirming in mouse models that cells from HER2 - positive breast cancers became resistant to anti-HER2 treatment when implanted into the brain but not into other tissues, the investigators found that HER3 is overexpressed in brain metastases of HER2 - positive breast cancers from both mice and human patients.

The next step was to find out which role Shp2 and its target genes play in human patients with breast cancer.

To uncover how groups of cancer cells achieve functional diversity (through RNA) to survive chemotherapy, Lopez - Diaz dosed dishes of human pre-cancer and metastatic breast cancer cells with the cancer drug paclitaxel for a week and then removed the drug for a few weeks, mimicking the treatment cycle for a cancer patient.

Chemotherapy is a key part of the standard treatment regimen for triple - negative breast cancer patients whose cancer lacks expression of estrogen and progesterone receptors and the human epidermal growth factor receptor 2...

These kind of mice are an extraordinary resource for modeling human disease; for instance, research has found that mice that are genetically mutated to carry the BRCA1 gene (a human breast cancer gene) behave more similarly to human cancer patients than those mice who have had a tumor physically transplanted in.

To evaluate the role of miR - 142 in the growth of human breast cancers initiated by the human BCSCs, we infected human BCSCs isolated from a patient - derived human breast cancer xenograft (PDX) with the anti-miR-142-3p-expressing lentivirus or the control lentivirus.

Primary human breast cancer samples were obtained from the Dana - Farber Cancer Institute with patients» consent and institutional review board appcancer samples were obtained from the Dana - Farber Cancer Institute with patients» consent and institutional review board appCancer Institute with patients» consent and institutional review board approval.

Importantly, however, we don't view our dog patients as test subjects for cancer research, but they can help us to better understand breast carcinoma in both dogs and humans and fight it more effectively.»

While human doctors and veterinarians are usually thought to keep to their own corners of the animal kingdom, more are seeing the same maladies in their patients — from breast cancers to addictions to eating disorders — causing the two disciplines to increasingly team up to crack medical mysteries.