Parabens can mimic estrogen, and have been detected in
human breast cancer tissue.
«[H] igh LDL receptor content in
human breast cancer tissue seems to indicate a poor prognosis, suggest [ing] that breast tumours rich in LDL receptors may grow rapidly» in the body.
Immunohistochemistry of paraffin - embedded
human breast cancer tissue slide using 10379 -1-AP (SNRPD3 Antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemistry of paraffin - embedded
human breast cancer tissue slide using 66240 -1-Ig (beta Tubulin antibody at dilution of 1:400 (under 10x lens)
The findings, now published in PLOS Genetics, reveal how mice can actually mimic
human breast cancer tissue and its genes, even more so than previously thought, as well as other cancers including lung, oral and esophagus.
Not exact matches
Three - dimensional models of living
tissue will advance understanding of
human breast development as well as the growth of
breast cancer.
To test this idea, the researchers utilized two mouse models of
human breast cancer metastasis and found dormant disseminated tumor cells residing upon the membrane microvasculature of lung, bone marrow and brain
tissue.
In tests on
human breast cancer cells and in special immunodeficient mice with
tissue grafts, the scientists found that both agents interfered with genes involved with
breast cancer cell growth, resulting in more
cancer cells.
After confirming in mouse models that cells from HER2 - positive
breast cancers became resistant to anti-HER2 treatment when implanted into the brain but not into other
tissues, the investigators found that HER3 is overexpressed in brain metastases of HER2 - positive
breast cancers from both mice and
human patients.
On Capitol Hill last week, Weinberg, an expert in the molecular biology of
cancer, pointed out to the Congressional Biomedical Research Caucus that the major advances in understanding
human cancer genetics had come, not from studying
breast tissue, but from studying cow warts, worm vulvas, fruitfly retinas, and a chicken virus.
Using cutting - edge techniques enabled by next - generation sequencing, the authors generated complete methylome maps at single nucleotide resolution in a low - passage
breast cancer cell line and normal
breast tissue (primary
human mammary epithelial cells).
A
tissue culture study of
human breast -
cancer cells found that epigallocatechin gallate, or EGCG, an active compound in green tea, protects against some forms of
breast cancer by regulating estrogen receptors on
breast cells and inhibiting growth and reproduction of estrogen - dependant
breast -
cancer cells.