Tags: aspirin, Bezos, bioengineering,
Breast Cancer, Cameron Turtle, Cancer etiology - prevention - outcomes, CAR t -
cell, Clinical Research, Colorectal Cancer, genome, hiv, hiv vaccine, hiv vaccine trials network,
Human Biology, immunology, Jason Bielas, Lawrence Corey, Matthias Stephan, merkel
cell carcinoma, metastasis, Molecular basis of cancer, mylotarg, Obliteride, Paul Nghiem, philanthropy, Polly A Newcomb, Public Health Sciences, RNA, Ruth Etzioni, Soheil Meshinchi, Steven Henikoff, Transplant and Immunotherapy, Tumor specific translational research, Vaccine and Infectious Disease, Vaccine development - Viral cancers
Flavopiridol inhibits several cellular kinases and has demonstrated cytostatic and cytotoxic activity in vitro and in vivo in numerous
human tumor
cell lines and xenograft models (including
human breast, prostate, and lung
carcinoma) at clinically achievable concentrations.
Studies of Gluts in
human tumors have shown a significant increase in the abundance of Glut1 and Glut3 mRNA in cancers of the esophagus, colon, and pancreas, overexpression of Glut1 and Glut3 mRNA and Glut1 protein expression in head and neck tumors and Glut1 protein overexpression in
breast and renal
cell carcinomas