Sentences with phrase «human cancer cell»

(Source) Another study examined the inhibitory effects of clove ethyl acetate extract on human cancer cell lines.

There are also petri dish studies that suggest gamma oryzanol may help lower cholesterol, and along with other compounds found in the rice bran, which is what makes brown rice brown, may inhibit human cancer cell growth through antioxidant means, anti-proliferative and pro cancer cell suicide mechanisms, immune system modulation, and increasing barrier protection, but again this is all just in test tubes, not people.

Seaweed inhibits human cancer cell growth, and this new study suggests it may even have a therapeutic potential for people battling liver cancer.

In another study, 11 human cancer cell lines (carcinomas and glioblastomas) were exposed to ascorbic acid in which 55 % of the cell lines were more susceptible (EC50 ≤ 20 mmol / L) and 45 % were more resistant (EC50 > 20 mmol / L) to incubation.

Anti-proliferative action of endogenous dehydroepiandrosterone metabolites on human cancer cell lines..

Azacytidine and Decitabine induce gene - specific and non-random DNA demethylation in human cancer cell lines

Mueller H, Kassack MU, Wiese M. Comparison of the usefulness of the MTT, ATP, and calcein assays to predict the potency of cytotoxic agents in various human cancer cell lines.

Using human cancer cell lines helps, but the crucial interplay between the cancers and their host environments is absent.

Inhibition of growth, production of insulin - like growth factor - II (IGFII), and expression of IGF - II mRNA of human cancer cell lines by antagonistic analogs of growth hormone - releasing hormone in vitro.

In studies using human cancer cell lines, a new, never - described compound known as BMH - 21 destroyed this critical communication pathway.

NCI's efforts to develop new laboratory models of human cancer includes vastly increasing the number of human cancer cell lines (grown as two - dimensional and three - dimensional cultures) and patient - derived tumor xenografts.

To determine whether the reactivation of methylation - silenced genes by EGCG is a general phenomenon that also occurs in other cell lines, we studied the effects of EGCG treatment on the methylation status and mRNA levels of p16INK4a or RARβ in three other human cancer cell lines (Fig. 3C) ⇓.

McKay and Tsai searched human cancer cell lines and found a human version of nucleostemin.

For this reason, the National Cancer Institute maintains a library of 60 authenticated human cancer cell lines for the purposes of research, called the NCI - 60.

«We've seen this in six different types of human cancer cell lines in the lab,» Choudhury said.

The resulting «map» of gene - drug interactions allowed the researchers to accurately predict the responses of multiple human cancer cell lines to different chemotherapy agents based on the cell lines» genetic profiles and also revealed new genetic factors that appear to determine the response of breast and ovarian tumor cells to common classes of chemotherapy treatment.

To validate their computer modeling predictions, researchers performed experiments in human cancer cell lines, mouse liver samples and primary human hepatocytes.

The next steps will be to test these combinations in more human cancer cell types and eventually in mouse models.

In earlier studies involving animal models and human cancer cell lines, researchers found that breast cancer spreads when three specific cells are in direct contact: an endothelial cell (a type of cell that lines the blood vessels), a perivascular macrophage (a type of immune cell found near blood vessels), and a tumor cell that produces high levels of Mena, a protein that enhances a cancer cell's ability to spread.

By studying human cancer cells and animal models of cancer in the lab, our researchers have shown that loss of PTEN leads to high levels of PI (3,4) P2, which could result in hyperactivation of AKT.

In addition, they injected mice with human cancer cells and found that the tumors grown in mice could be inhibited with PD173074.

Genetically reprogramming late - stage human cancer cells to a stem - cell state enabled them to force the reprogrammed cells to progress to an early cancerous state, revealing secreted blood biomarkers of early - stage disease along the way.

The tissue barrier, about four cells deep, was made from «BeWo» human cancer cells.

Avivi's team has found out that fibroblast skin cells from the armpits of the rats can kill human cancer cells in a dish.

He had been experimenting with human cancer cells, microbes, and mothers» milk.

In studies of mice injected with human cancer cells, the drug appeared to work according to plan.

They tested these drugs one at a time for lethal interaction with 112 different tumor - suppressor gene mutations in human cancer cells growing in the lab.

Using in vitro, or test tube, experiments, the researchers applied these chemicals to human cancer cells to measure changes of estrogen receptor - and androgen receptor - target genes and transcriptional activity.

The size difference between tumor and healthy circulating DNA was initially discovered in animal tumor models created by inducing tumors with human cancer cells.

They placed the human cancer cells into the incubator and lowered the oxygen to a level comparable to that in a tumour.

The researchers ended up with 172 drug - gene mutation combinations that successfully killed both yeast and human cancer cells.

A controversial weed killer may inadvertently act as a fertilizer for human cancer cells — and scientists are closer to understanding how.

Now, scientists have modified Salmonella bacteria to trigger a particularly powerful immune response against human cancer cells implanted in mice, shrinking the tumors and — for the first time — preventing them from metastasizing.

Slashing the amount of HSF1 in several lines of human cancer cells diminished growth and survival.

As controls, fibroblasts and secretions from normal lab rats, mice, and another rodent called the spiny mouse were powerless to stop the human cancer cells growing.

The fibroblasts rapidly killed the human cancer cells.

We don't know if human cancer cells that lack Hsp90 also change their chromosomes.

The Dicty cells were taken from the single - celled organisms that make up slime molds, whereas the HL60 cells are highly studied human cancer cells.

But the cells didn't appear to be human, they were 10 times smaller than human cancer cells.

Their preliminary findings indicate that MUS81 - induced movement of DNA to the cytosol also occurs in human cancer cells, including prostate cancer, breast cancer, colorectal cancer, uterine cancer, leukemia, and melanoma cells.

According to its developers, the technique can be applied to assess mutation dynamics in other types of cells, even human cancer cells.

To see what power nucleostemin wields, the researchers looked at its effects in both rat stem cells and human cancer cells.

With molecular biologist Gregory Hannon of Cold Spring Harbor Laboratory in New York state, Elledge developed genetic tools that examine how genes function in human cancer cells.

For more than 25 years, scientists examining cultures of human cancer cells have occasionally spotted cells tucked within other cells.

«First, we must bear in mind that the study was done on human cancer cells cultured in the laboratory, since it would be unethical to do it in humans.

In the test tube, the nanogenerators killed leukaemia, lymphoma, breast, ovarian, neuroblastoma, and prostate human cancer cells.

By suppressing genes that are active in the developing embryo, silenced just before birth, and re-activated years later in many advanced cancers, the let - 7 family of «microRNAs» — tiny snippets of RNA that can put the brakes on expression of selected genes — appears to prevent human cancer cells from reasserting their prenatal capacity to divide rapidly, travel and spread.

They also found that drugs that target this newly identified cancer pathway can prevent tumor growth, both in human cancer cells and mice with a form of brain cancer.

Combinatorial effect of maytansinol and radiation in Drosophila and human cancer cells.

All well and good, but what about human cancer cells?