Inhibition of growth, production of insulin - like growth factor - II (IGFII), and expression of IGF - II mRNA of
human cancer cell lines by antagonistic analogs of growth hormone - releasing hormone in vitro.
Not exact matches
To see whether
cancer stem
cell renewal involves a chain of events similar to that used
by embryonic stem
cells, and whether the process was affected
by oxygen levels, Semenza and graduate student Chuanzhao Zhang focused their studies on two
human breast
cancer cell lines that responded to low oxygen
by ramping up production of the protein ALKBH5, which removes methyl groups from mRNAs.
A team of researchers in Germany and Denmark led
by Steven Johnsen, Professor at the University Medical Center Göttingen, Germany, used
human prostate
cancer cell lines and depleted them of the DNA - binding protein CHD1.
The goal of the first experiment was to see whether lncRNAs are differentially expressed in prostate
cancer by measuring total RNA from prostate
cancer cell lines and normal epithelial prostatic
cells using NCode
human ncRNA array and SurePrint G3
human lncRNA microarrays.
To determine whether the reactivation of methylation - silenced genes
by EGCG is a general phenomenon that also occurs in other
cell lines, we studied the effects of EGCG treatment on the methylation status and mRNA levels of p16INK4a or RARβ in three other
human cancer cell lines (Fig. 3C) ⇓.
Here, we show that a non-adherent, stem - like, and metastatic CSC - enriched subpopulation could be isolated
by exposing
human metastatic breast
cancer cell lines to cycles of chronic hypoxia followed
by reoxygenation.
Using cutting - edge techniques enabled
by next - generation sequencing, the authors generated complete methylome maps at single nucleotide resolution in a low - passage breast
cancer cell line and normal breast tissue (primary
human mammary epithelial
cells).
Ab7291 staining alpha tubulin in
human breast
cancer cell line by ICC / IF (Immunocytochemistry / Immunofluorescence).
HuH - 7 (
human HCC), HepG2 (
human hepatocellular blastoma), 293T (
human embryonic kidney fibroblast), HeLa (
human cervical
cancer cells), NIH 3T3 (murine fibroblast), and HCT116 (human colon cancer) and its derived cell line HCT116 p21 − / − (kindly provided by Dr. B. Vogelstein, Howard Hughes Medical Institute, Chevy Chase and the Sydney Kimmel Comprehensive Cancer Center of the Johns Hopkins University School of Medicine, Baltimore, MD
cancer cells), NIH 3T3 (murine fibroblast), and HCT116 (
human colon
cancer) and its derived cell line HCT116 p21 − / − (kindly provided by Dr. B. Vogelstein, Howard Hughes Medical Institute, Chevy Chase and the Sydney Kimmel Comprehensive Cancer Center of the Johns Hopkins University School of Medicine, Baltimore, MD
cancer) and its derived
cell line HCT116 p21 − / − (kindly provided
by Dr. B. Vogelstein, Howard Hughes Medical Institute, Chevy Chase and the Sydney Kimmel Comprehensive
Cancer Center of the Johns Hopkins University School of Medicine, Baltimore, MD
Cancer Center of the Johns Hopkins University School of Medicine, Baltimore, MD; ref.
In a series of lab experiments with
cell lines,
human xenograft tumors in mice and primary
human prostate
cancer samples, the researchers demonstrated that miR - 34a inhibits prostate
cancer stem
cells by suppressing CD44.
canSAR contains information on the entire
human proteome — the protein equivalent of the
human genome - as well as linking to information on more than 1,000
cancer cells lines, used
by researchers to study the effect of new drugs in the lab.
On the basis of studies on the XMRV - producing
human prostate
cancer cell lines CWR22Rν1 and CWR - R1 and their progenitor tumour xenograft CRW22, they concluded that XMRV infections were caused
by contamination during in vivo passaging in nude mice.
Important features of XMRV biology include (1) tropism for a variety of
cell lines, including prostate
cancer DU145 and LNCaP
cells [27], [43], [48], and
human neural
cell types [57], (2) adaptations that promote growth in prostate epithelium and
human - derived prostate
cancer cell lines including an androgen response element in the promoter region [58] and downregulation of APOBEC3G [59], and (3) cellular effects with potential oncogenic properties including increased tumor aggressiveness mediated
by downregulation of p27 [60] and differential regulation of several microRNAs [61].