Sentences with phrase «human cancer cells like»

NSG mice have impaired immune systems, so they can accept and grow human cancer cells like those grown in glass dishes.

Not exact matches

Moreover, epalrestat, a drug that inhibits AKR1B1 and is approved in Japan to treat peripheral neuropathies associated with diabetes, was similarly able to block the growth and metastasis of human basal - like breast cancer cells.

Compared to a control (left), epalrestat treatment (right) reduces the number of metastatic tumors (arrowheads) in the lungs of mice injected with human basal - like breast cancer cells.

The stem cells, derived from human umbilical cord - blood and coaxed into an embryonic - like state, were grown without the conventional use of viruses, which can mutate genes and initiate cancers, according to the scientists.

«There are still many questions left to answer but we now know that oxygen poor environments, like those often found in advanced human breast cancers serve as nurseries for the birth of cancer stem cells,» says Gregg Semenza, M.D., Ph.D., the C. Michael Armstrong Professor of Medicine and a member of the Johns Hopkins Kimmel Cancer Ccancer stem cells,» says Gregg Semenza, M.D., Ph.D., the C. Michael Armstrong Professor of Medicine and a member of the Johns Hopkins Kimmel Cancer CCancer Center.

Another is that the transplanted bits of tumor act nothing like cancers in actual human brains, Fine and colleagues reported in 2006: Real - life glioblastomas grow and spread and resist treatment because they contain what are called tumor stem cells, but tumor stem cells don't grow well in the lab, so they don't get transplanted into those mouse brains.

Like these cell lines, not all human bladder cancers share the same genetic changes.

One week after a breakthrough finding, scientists report they can reprogram human skin cells to behave like embryonic stem cells without a growth factor known to cause cancer

When tested in laboratory samples of leukemia cells and in animals with human - like leukemia, the approach caused cancer cells to die much more quickly than with conventional targeted therapies.

Telomerase is turned off in most human cells, but cancer cells often must reactivate it so that they can keep dividing like crazy.

The Xie Lab demonstrated that differentiation - defective Drosophila ovarian germline stem cells (GSCs), behaving like human cancer stem cells, can out - compete normal stem cells for a position in the niche.

The Wnt / beta - catenin pathway regulates self - renewal of cancer stem - like cells in human gastric cancer.

Here, we show that a non-adherent, stem - like, and metastatic CSC - enriched subpopulation could be isolated by exposing human metastatic breast cancer cell lines to cycles of chronic hypoxia followed by reoxygenation.

Aug 8, 2008 Two New Predisposition Genes For Breast, Thyroid And Kidney Cancers Could Lead to More Accurate Diagnosis and Earlier Detection of These Cancers Charis Eng, MD, PhD, Sondra J and Stephen R Hardis Endowed Chair of Cancer Genomic Medicine and Chair, GMI, and her team published in the Aug 8, 2008 issue of the American Journal of Human Genetics that germline mutations in SDHB and SDHD, which play key roles in the mitochondria (the cell's power houses), predispose to Cowden and Cowden - like syndromes.

• Detect Zika virus in blood and urine samples within hours and distinguish between its African and American strains • Distinguish between Zika and dengue • Discriminate different types of bacteria, like E. coli • Detect cancer cell mutations • Detect antibiotic resistance genes • Read human genetic information from saliva sample

Stem cell methodologies like culture conditions, sorting, and how to grow and transfect cells are all tools we can apply now to human brain cancers.

«Basically, this study shows that the genetic makeup of individual human embryonic stem cell lines is unique in the numbers of copies of certain genes that may control traits and things like disease susceptibility,» said Teitell, who also is an associate professor of pathology and laboratory medicine and a researcher at UCLA's Jonsson Comprehensive Cancer Center.

Inhibition of growth, production of insulin - like growth factor - II (IGFII), and expression of IGF - II mRNA of human cancer cell lines by antagonistic analogs of growth hormone - releasing hormone in vitro.

Researchers here are cataloguing what makes cancer cells dangerous down at the level of individual genetic changes, how and why pathogens like malaria evolve to be more (or less) harmful and how humans adapt to those changes.

Interestingly, long - term — cultured human epithelial cancer cells in clonal cultures also form holoclones, meroclones, and paraclones, and tumor cell holoclones have been hypothesized to harbor stem - like cells or cancer stem cells.

This was nuts versus human liver cancer cells, like they did in the fruit study.

Like human cancers, the disease is caused by the uncontrollable growth of abnormal cells on or...

Like human cancers, the disease is caused by the uncontrollable growth of abnormal cells on or within the body.

Just like the ever - growing list of disorders, it is known to treat in humans, acupuncture also plays a big role in combating some of the side effects that sprout as a result of cancer cells in a dog's body.