Sentences with phrase «human cell culture systems»

Specifically, the Ignatius laboratory will study tumorigenic cell populations that self - renew and metastasize using a combination of zebrafish, murine xenograft and human cell culture systems.

Not exact matches

2 - D cell - culture and mouse experiments also provided key evidence of the virus's modus operandi; although the rodent brain doesn't harbor the full contingent of human neural stem cells, it has blood vessels and immune - system components that organoids lack.

They found that indeed, they do, and that stimulating these cells led them to kill cells infected with HIV - 1 derived from latently infected cells, both in culture and in mice engineered to have a human immune system.

protected animals»); studies on in vitro systems (whole perfused organs, tissue slices, cell and tissue cultures, and subcellular fractions); and human studies (including estimations of occupational and environmental exposure, postmarketing surveillance, epidemiology, and the ethical and strictly controlled use of human volunteers).

Cell culture systems used today also do not faithfully represent the features of human neurons.»

Expanding from their previous studies with mice, the researchers first established that under specific conditions, culturing human embryonic stem cells with fibroblast growth factor 2 (FGF2) leads to neural differentiation particular to the midbrain / hindbrain region — the location of the cerebellum — within three weeks, and the expression of markers for the cerebellar plate neuroepithelium — the part of the developing nervous system specific for the cerebellum — within five.

AHERF Neurosciences Grant (G9410 -020-Y01)- Co-PI; «Differential expression and sorting of the neuron - specific class III b - tubulin isotype in human neuronal and neuroendocrine tumor cell lines maintained in an organ culture system».

The CRISPR / Cas system is amazingly versatile and has proven to edit the genome effectively not only in mice and flies, but also in monkeys and, yes, in human cultured cells.

It facilitates self - renewal of both pluripotent human embryonic stem cells and induced pluripotent stem cells in a chemically defined, feeder - free and animal - protein free cell culture system.

Cellartis human iPS cells from the ChiPSC22 line (Figure 2) and the ChiPSC18 line (Figures 3 — 7 and Table I) were grown in the Cellartis DEF ‑ CS 500 Culture System before editing.

The DEF - CS system is a robust culture system for efficient expansion of human induced pluripotent stem (iPS) cells in a feeder - free and defined environment.

First, cells from Cellartis Human iPS Cell Line 22 (ChiPSC22) were modified to stably express AcGFP1, then these cells were cultured using the DEF ‑ CS culture system in a 48 - well plate.

Laminin - 521 human stem cell matrix makes pluripotent stem cell culture easy in a defined, xeno - free and biologically relevant cell culture system.

Since human embryonic stem cells grow in an adherent culture system, for cells being reprogrammed this «new culture system» is an adherent culture system (to try and mimic the conditions the embryonic stem cells want to be happy).

7/16/2008 Improved Culture System for Hepatitis C Virus Infection A University of California, San Diego School of Medicine researcher has developed the first tissue culture of normal, human liver cells that can model infection with the Hepatitis C virus (HCV) and provide a realistic environment to evaluate possible... Culture System for Hepatitis C Virus Infection A University of California, San Diego School of Medicine researcher has developed the first tissue culture of normal, human liver cells that can model infection with the Hepatitis C virus (HCV) and provide a realistic environment to evaluate possible... culture of normal, human liver cells that can model infection with the Hepatitis C virus (HCV) and provide a realistic environment to evaluate possible... More...

To identify the JSRV receptor in lung cells, Miller developed a system using cultured hamster cells that contain small pieces of human DNA.

The «heart - on - a-chip,» which builds off previous successful iCHIP research on the peripheral and central nervous systems, involves the use of human cardiac cells cultured for up to nine days on the engineered chip.

The Human Emulation System offers researchers a new standard for predicting how a human may respond to diseases, medicines, chemicals, and foods — with greater precision and control than today's cell culture or animal - based testing approaHuman Emulation System offers researchers a new standard for predicting how a human may respond to diseases, medicines, chemicals, and foods — with greater precision and control than today's cell culture or animal - based testing approahuman may respond to diseases, medicines, chemicals, and foods — with greater precision and control than today's cell culture or animal - based testing approaches.

Due to the large number of hES cells and human induced Pluripotent Stem (hiPS) cells needed by I - Stem's research groups, the development of large - scale culture systems for expansion and differentiation of those cells is critical.

About the «Human Emulation System» Powered by Organs - On - Chips Technology Based on the Organs - on - Chips technology, Emulate has created a new living Human Emulation System ™ that provides a real - time window into the inner workings of human biology and disease — offering researchers a new technology designed to predict human response with greater precision and detail than today's cell culture or animal - based experimental tesHuman Emulation System» Powered by Organs - On - Chips Technology Based on the Organs - on - Chips technology, Emulate has created a new living Human Emulation System ™ that provides a real - time window into the inner workings of human biology and disease — offering researchers a new technology designed to predict human response with greater precision and detail than today's cell culture or animal - based experimental tesHuman Emulation System ™ that provides a real - time window into the inner workings of human biology and disease — offering researchers a new technology designed to predict human response with greater precision and detail than today's cell culture or animal - based experimental teshuman biology and disease — offering researchers a new technology designed to predict human response with greater precision and detail than today's cell culture or animal - based experimental teshuman response with greater precision and detail than today's cell culture or animal - based experimental testing.

By developing a simple chemically defined culture system permitting efficient differentiation of numerous human iPS cell lines toward cells of a mature hepatic state, we now demonstrate the possibility of modeling groups of diseases of non-neuronal origin whose phenotypes are a consequence of complex protein dysregulation within adult cells.

Dienogest, a synthetic progestin, inhibits prostaglandin E (2) production and aromatase expression by human endometrial epithelial cells in a spheroid culture system..

Antioxidants have been shown to reduce bio-markers of oxidative cell damage in cell culture systems, as well as in many animal models and human studies.

Flavonoids have been shown to reduce biomarkers of oxidative cell damage in cell culture systems, animal models and human studies.

This study used a model cell culture system that represents what happens in an animal or human.

«Among other things, the NAS Report calls for the Environmental Protection Agency to implement a toxicity testing strategy that is based on non-mammalian systems and human cells in culture [in vitro],» Rene explains.