Sentences with phrase «human cell surface»

The alternate approach is to devise approaches which block entrance of the virus by directing agents at the human cell surface sites which serve as docking sites for the virus (i.e., shut the door).

«These changes look like large membrane bubbles on the human cell surface, noted here as blebs,» said Shanks.

Cells were stained with antibodies specific for human cell surface markers: CD326 / ESA - FITC, CD24 - PE, and CD44 - PE - Cy7 (BD Pharmingen, San Jose, CA, USA).

Not exact matches

The human body has about 1,000 kinds of such receptors, structures on the surface of cells, which let the body respond to a wide variety of chemical signals, like adrenaline.

For the first time, researchers used human cells to build a model of the surface of the eye that's equipped with a fake eyelid that mimics blinking.

The «acid spit» chewed up surface proteins that the pathogen uses to attach to and invade human cells.

But the London researchers have shown a few small changes in the shape of a surface protein were all it took to enable the bird version of Spanish flu to bind onto human cells.

To begin the research, the scientists screened human DIPG tumor cultures for surface molecules that could act as targets for CAR - T cells.

That gene encodes a sugar - studded protein on the virus's outer surface that helps the virus stick to and invade human cells.

Researchers studied the structure of proteins from one strain of the H7N9 virus that caused the outbreak and tested how strongly one of the proteins bound to molecules on the surfaces of bird and human cells.

BABY BLUE Using human eye cells, researchers fashioned an artificial eye surface that could be used to study and test treatments for eye diseases.

Researchers at Harvard T. H. Chan School of Public Health and the Broad Institute have identified a protein on the surface of human red blood cells that serves as an essential entry point for invasion by the malaria parasite.

Scientists have identified a protein on the surface of human red blood cells that serves as an essential entry point for invasion by the malaria parasite.

So his team looked for cells with vasa still on their surface in human ovarian tissue.

Thirdhand smoke — the noxious residue that clings to virtually all surfaces long after the secondhand smoke from a cigarette has cleared out — causes significant genetic damage in human cells.

A study led by researchers from Lawrence Berkeley National Laboratory has found for the first time that thirdhand smoke — the noxious residue that clings to virtually all surfaces long after the secondhand smoke from a cigarette has cleared out — causes significant genetic damage in human cells.

Currently, seasonal flu vaccines are designed to induce high levels of protective antibodies against hemagglutinin (HA), a protein found on the surface of the influenza virus that enables the virus to enter a human cell and initiate infection.

Since then, evidence has emerged that the crucial human proteins are HLA antigens, proteins that appear on the surfaces of cells and vary from person to person.

MERS CoV (CoV stands for coronavirus) has on its surface an array of spike - shaped proteins that bind to host cells — specifically to receptor proteins called DPP4 on the surface of cells that line human airways.

A radio - labeled human antibody binds to the viral gp41 protein expressed on the surface of the HIV - infected human lymphocyte and the cell is killed by alpha radiation delivered by the antibody.

They found that adding a hydrocinnamoyl ester on to the sugar stabilized the ligand and kept it close to the surface of the antigen - presenting cell, thereby enhancing its ability to dock with and stimulate human iNKT cells.

The health of the human vagina depends on a symbiotic / mutually beneficial relationship with «good» bacteria that live on its surface feeding on products produced by vaginal skin cells.

With gene - editing tools such as CRISPR, scientists can now eliminate immune - provoking sugars from the surface of pig cells, introduce human genes that regulate blood coagulation to prevent dangerous clots, and snip out viral sequences that some fear could infect a human host.

The use of cell surface markers to isolate specific cell populations is one common method for separating cells; however, isolating live cells based on their RNA expression is a powerful new way enabling the study of small cell niches in nongenetically modified animal models and human tissue.

The researchers are the first to grow human vaginal skin cells in a dish in a manner that creates surfaces that support colonization by the complex good and bad communities of bacteria collected from women during routine gynecological exams.

Researchers at Karolinska Institutet have identified cell surface markers specific for the very earliest stem cells in the human embryo.

Then, by placing surface proteins of each HCV virus onto these pseudoviruses, the researchers were able to efficiently infect human cells with the HCV strains in tissue culture.

Plasmodium parasites infect human red blood cells and gain entry via receptors on the cell surface.

A study of the way malaria parasites behave when they live in human red blood cells has revealed that they can rapidly change the proteins on the surface of their host cells during the course of a single infection in order to hide from the immune system.

In human medicine EGFR is frequently used as the target of cancer immunotherapy because many cancer cells bear this receptor on their surface.

«Making the movements of HIV visible so that we can follow, in real time, how surface proteins on the virus behave will hopefully tell us what we need to know to prevent fusion with human cells — if you can prevent viral entry of HIV into immune cells, you have won,» says Dr. Blanchard, who is also associate director of Weill Cornell's chemical biology program.

The Discher Lab has since shown that a protein on human cells called CD47 functions as a «marker of self» by interacting with a protein on the surface of macrophages called SIRPA.

These organoids form all of the cell types present in human intestine, but they grow as cysts surrounded by thick extracellular matrix gels with their «apical» cell surface (which is normally exposed to the content of the gut) facing an enclosed lumen.

MCC is associated with a virus, the Merkel cell polyomavirus, which is quite common, often found on normal human skin and surfaces that are frequently touched, Dr. Nghiem says.

Dr. Shiloh and his team currently are working to discover the human cell - surface receptors for Mtb that are involved in the bacteria's M - cell translocation, as well as to determine the exact machinery used by the cell to move the bacteria from the surface to the bottom of the cell.

He then injected human endothelial cells into the collagen structures of blood vessels to recolonise the surfaces of blood vessels.

In the new work, the researchers added serum from Finnish narcolepsy patients who had received Pandemrix to cells that were engineered to display human hypo cretin receptor 2 on their surface.

She found a gene for what's known as the major histocompatibility complex (MHC)-- cell surface molecules that help the immune system recognize foreigners — that was remarkably similar to one in humans that allows infected people to keep the virus in check for decades.

Skeletal muscle cells isolated using the ERBB3 and NGFR surface markers (right) restore human dystrophin (green) after transplantation significantly greater than previous methods (left).

Bartenschlager injected this «replicon,» which codes for HCV's nonstructural proteins but not its core or surface proteins, into human cells.

Additional experiments, including gene knockdown, surfaced prohibitin as a likely infection aide; prohibitin is a multi-functional protein found in human cells and in many other organisms.

T. cruzi is already known to disguise its cell surface with human proteins and sugars: apoptosis would be yet another weapon in the arsenal that helps it evade the immune system.

Researchers at the Babraham Institute and the Karolinska Institute report today in Cell Stem Cell that they have identified a set of proteins (molecular «flags») that are present on the surface of either naïve or primed human embryonic stem cells.

The new coronavirus latches onto a protein called dipeptidyl peptidase 4, or DPP4, which decorates the surface of many cells, including some in human airways and kidneys, Bart Haagmans of Erasmus Medical Center in Rotterdam, the Netherlands, and colleagues report in the March 14 Nature.

Researchers have identified a set of molecular «flags» that are present on the surface of human stem cells.

The protein LecA on the surface of the bacteria binds to sugar on special lipid molecules, so - called Gb3 lipids, which are present in the outer membrane of human cells.

The research team found that Alphamers not only bind strep and recruit anti-Gal antibodies to the bacterial surface, they also helps human immune cells engulf and kill the Alphamer - coated bacteria.

Human - associated bacteria disperse into and throughout the built environment by three primary mechanisms: (1) direct human contact with indoor surfaces; (2) bioaerosol particle emission from our breath, clothes, skin and hair; and (3) resuspension of indoor dust containing previously shed human skin cells, hair and other bacteria - laden partiHuman - associated bacteria disperse into and throughout the built environment by three primary mechanisms: (1) direct human contact with indoor surfaces; (2) bioaerosol particle emission from our breath, clothes, skin and hair; and (3) resuspension of indoor dust containing previously shed human skin cells, hair and other bacteria - laden partihuman contact with indoor surfaces; (2) bioaerosol particle emission from our breath, clothes, skin and hair; and (3) resuspension of indoor dust containing previously shed human skin cells, hair and other bacteria - laden partihuman skin cells, hair and other bacteria - laden particles.

Weiss A, Imboden J, Shoback D, Stobo J. Role of T3 surface molecules in human T - cell activation: T3 - dependent activation results in an increase in cytoplasmic free calcium.

HLA (human leukocyte antigen)- markers on the surface of a body's cell that identify the cell as one's own (as opposed to a foreign cell) and prevent the immune system from attacking itself.