Sentences with phrase «human cell surface proteins»

Not exact matches

The «acid spit» chewed up surface proteins that the pathogen uses to attach to and invade human cells.

But the London researchers have shown a few small changes in the shape of a surface protein were all it took to enable the bird version of Spanish flu to bind onto human cells.

That gene encodes a sugar - studded protein on the virus's outer surface that helps the virus stick to and invade human cells.

Researchers studied the structure of proteins from one strain of the H7N9 virus that caused the outbreak and tested how strongly one of the proteins bound to molecules on the surfaces of bird and human cells.

Researchers at Harvard T. H. Chan School of Public Health and the Broad Institute have identified a protein on the surface of human red blood cells that serves as an essential entry point for invasion by the malaria parasite.

Scientists have identified a protein on the surface of human red blood cells that serves as an essential entry point for invasion by the malaria parasite.

Currently, seasonal flu vaccines are designed to induce high levels of protective antibodies against hemagglutinin (HA), a protein found on the surface of the influenza virus that enables the virus to enter a human cell and initiate infection.

Since then, evidence has emerged that the crucial human proteins are HLA antigens, proteins that appear on the surfaces of cells and vary from person to person.

MERS CoV (CoV stands for coronavirus) has on its surface an array of spike - shaped proteins that bind to host cells — specifically to receptor proteins called DPP4 on the surface of cells that line human airways.

A radio - labeled human antibody binds to the viral gp41 protein expressed on the surface of the HIV - infected human lymphocyte and the cell is killed by alpha radiation delivered by the antibody.

Then, by placing surface proteins of each HCV virus onto these pseudoviruses, the researchers were able to efficiently infect human cells with the HCV strains in tissue culture.

A study of the way malaria parasites behave when they live in human red blood cells has revealed that they can rapidly change the proteins on the surface of their host cells during the course of a single infection in order to hide from the immune system.

«Making the movements of HIV visible so that we can follow, in real time, how surface proteins on the virus behave will hopefully tell us what we need to know to prevent fusion with human cells — if you can prevent viral entry of HIV into immune cells, you have won,» says Dr. Blanchard, who is also associate director of Weill Cornell's chemical biology program.

The Discher Lab has since shown that a protein on human cells called CD47 functions as a «marker of self» by interacting with a protein on the surface of macrophages called SIRPA.

Bartenschlager injected this «replicon,» which codes for HCV's nonstructural proteins but not its core or surface proteins, into human cells.

Additional experiments, including gene knockdown, surfaced prohibitin as a likely infection aide; prohibitin is a multi-functional protein found in human cells and in many other organisms.

T. cruzi is already known to disguise its cell surface with human proteins and sugars: apoptosis would be yet another weapon in the arsenal that helps it evade the immune system.

Researchers at the Babraham Institute and the Karolinska Institute report today in Cell Stem Cell that they have identified a set of proteins (molecular «flags») that are present on the surface of either naïve or primed human embryonic stem cells.

The new coronavirus latches onto a protein called dipeptidyl peptidase 4, or DPP4, which decorates the surface of many cells, including some in human airways and kidneys, Bart Haagmans of Erasmus Medical Center in Rotterdam, the Netherlands, and colleagues report in the March 14 Nature.

The protein LecA on the surface of the bacteria binds to sugar on special lipid molecules, so - called Gb3 lipids, which are present in the outer membrane of human cells.

Clone 1022 cells ezpress human CD4 protein on the cell surface and can be infected by most isolates of HIV.

Proteins on the surface of both the Plasmodium sporozoite and human host cells are likely to be important in this journey, but little is known about the exact interactions which occur.

He isolated the genes encoding proteins that confer immunological identity to the two main types of cells in the human immune arsenal: the CD4 protein, which dots the surface of helper T cells, and the CD8 protein, which adorns killer T cells.

The most potent of these, known as effector memory T cells, are activated by a group of proteins known as human leukocyte antigens (HLAs) on the surface of endothelial cells lining the donated organ's blood vessels.

Miller's group, including postdoctoral fellow Dr. Sharath Rai, graduate student Vladimir Vigdorovich and collaborators at the National Cancer Institute, identified the human version of the viral receptor, a cell - surface protein called HYAL2 that has been implicated in lung cancer.

HIV enters human cells using an envelope protein that binds to two cell - surface receptors and then pulls the viral membrane near the cell membrane.

The bacterium may, for example, bind with human proteins on its surface, thus appearing to be made up of human cells.

Like the bacteria that cause gonorrhea, members of T. pallidum have multiple copies of the gene coding for the proteins that allow them to adhere to human cells — perhaps, as in the case of gonorrhea, these genes allow T. pallidum to alter their surface proteins in order to escape recognition by the immune system.