Sentences with phrase «human cell types from»

Yours truly generated the DHS data set by starting with all of the DHS sites from 125 different human cell types from the ENCODE Project.

Not exact matches

Breastfeeding is contraindicated in infants with classic galactosemia (galactose 1 - phosphate uridyltransferase deficiency) 103; mothers who have active untreated tuberculosis disease or are human T - cell lymphotropic virus type I — or II — positive104, 105; mothers who are receiving diagnostic or therapeutic radioactive isotopes or have had exposure to radioactive materials (for as long as there is radioactivity in the milk) 106 — 108; mothers who are receiving antimetabolites or chemotherapeutic agents or a small number of other medications until they clear the milk109, 110; mothers who are using drugs of abuse («street drugs»); and mothers who have herpes simplex lesions on a breast (infant may feed from other breast if clear of lesions).

To determine how the cells switch from one type to another, they took three human uterine carcinosarcoma samples and sequenced the genomes of cells in two parts of each tumor: the carcinoma and sarcoma components.

The researchers detected this SMN long noncoding RNA, or lnc - RNA (pronounced «link RNA») for short, in human embryonic kidney cells, brain cell samples and neurons derived from the stem cells of healthy people and those with spinal muscular atrophy type I and II.

Trials of cells made from human embryonic stem cells are also poised to begin in people with type 1 diabetes and heart failure, the first time embryonic stem cells have been used in the treatment of major lethal diseases.

«However, because SIF - seq only requires DNA sequence from a mammal and can be used in a variety of cell types, it should be possible to compare the neuronal enhancers present in a large genomic region from human to the neuronal enhancers present in the orthologous chimpanzee region.

The study provides a new understanding of how, billions of years ago, the complex cell types that comprise plants, fungi, but also animals and humans, evolved from simple microbes.

TWO types of human ear cell have been grown in the lab from fetal stem cells.

Using a mathematical model known as the Ising model, invented to describe phase transitions in statistical physics, such as how a substance changes from liquid to gas, the Johns Hopkins researchers calculated the probability distribution of methylation along the genome in several different human cell types, including normal and cancerous colon, lung and liver cells, as well as brain, skin, blood and embryonic stem cells.

ACT is now performing early - phase clinical trials testing the safety of implanting retinal cells derived from human ES cells into the eye to treat certain types of blindness.

In the second Cell paper, researchers collaborated with scientists at the University of Cambridge, McGill University in Canada and several UK and European institutions to explore the role that epigenetics plays in the development and function of three major human immune cell types: CD14 + monocytes, CD16 + neutrophils and naïve CD4 + T cells, from the genomes of 197 individuCell paper, researchers collaborated with scientists at the University of Cambridge, McGill University in Canada and several UK and European institutions to explore the role that epigenetics plays in the development and function of three major human immune cell types: CD14 + monocytes, CD16 + neutrophils and naïve CD4 + T cells, from the genomes of 197 individucell types: CD14 + monocytes, CD16 + neutrophils and naïve CD4 + T cells, from the genomes of 197 individuals.

The researchers have compared various processes involved in gene expression, such as gene transcription and chromatin modification, and have repeated this in different tissues and cell types from both humans and mice.

A panel of small molecules that inhibit Zika virus infection, including one that stands out as a potent inhibitor of Zika viral entry into relevant human cell types, was discovered by researchers from the Perelman School of Medicine at the University of Pennsylvania.

In their latest study, they tested compounds against cells from nine different types of human cancer, including common types affecting blood, colon, breast, prostate, ovaries, kidneys, and lungs.

In addition to looking at mouse models of diabetes, the researchers also showed that exposure of human pancreatic islet cells — both from healthy donors and from patients with Type 1 diabetes — to fasting - mimicking diet in a dish stimulated insulin production.

Ozanne says that similar ageing effects have been identified in beta cells from people with type 2 diabetes, but she adds that her team have yet to prove this is linked to poor maternal diet in humans.

The scientists harvested the mutant hemagglutanin proteins from the cells and tested how strongly they bound to human - type and bird - type receptors.

We also reactivated insulin production in human pancreatic cells from type 1 diabetes patients.»

Beyond lung cancer, TiY is able to target TICs in 28 types of human cell lines derived from the central nervous system, melanoma, breast, renal, ovarian, colon, and prostate cancer.

Desgrosellier said the team will follow up with mouse models containing tumor fragments from patients to better reflect the diversity of cell types present in human disease.

From the moment of fertilization, building a human body involves a series of choices where cells generated by cell division must elect which of the myriad types of cell they will become.

Johns Hopkins researchers have developed a method to efficiently turn human stem cells into retinal ganglion cells, the type of nerve cells located within the retina that transmit visual signals from the eye to the brain.

«He identified a type of molecular sensor, which programmed T cells isolated from human blood with customized instructions for thwarting attack.

As it turns out, the missing link was a previously unknown type of light - sensitive cell in the human eye, distinct from the familiar rods and cones that are responsible, respectively, for night and color vision.

Of the 37 trillion cells in the typical human body, the ability to distinguish one type of cell from another isn't as straightforward as you may think.

Scientists have demonstrated a method for generating several key types of eye tissue from human stem cells in a way that mirrors whole eye development.

Stem cells obtained from human embryos seem to offer the best chance of new therapies, because unlike other stem cells they have the ability to morph into almost any type of tissue.

The researchers tested their technique on such cultivated stem cells of both a mature and immature type, and on donated human embryos left over from IVF treatments.

The device, part of the Lab's iCHIP (in - vitro Chip - Based Human Investigational Platform) project, simulates the central nervous system by recording neural activity from multiple brain cell types deposited and grown onto microelectrode arrays.

«Our group pioneered the development of cell culture technology for harvesting large numbers of stem cells from human bone marrow and human umbilical cord blood,» Dr. Yeh said, noting that stem cells from these two sources are abundant and can be guided into different types of cells using tissue engineering.

Furthermore, stem - cell lines from mice begin to lose their ability to produce many types of cells after as few as 20 generations, and researchers assume the same will prove true for stem cells from humans.

For the new study, the team used a cell - reprogramming technique (similar to those used to reprogram skin cells into stem cells) to generate human DRG - type sensory neurons from ordinary skin cells called fibroblasts.

To determine what types of animals hCoV - EMC can infect, Drosten and colleagues infected cells from humans, pigs, and a wide variety of bats, the key natural reservoirs of coronaviruses.

So, at the dawn of our universe — and I have to emphasize our universe, because there could be others — so, dawn of our universe, physicists think there was one type of force, one type of matter and that as the cosmos expanded, as space expanded, it cooled and things started to condense out like snow flakes, and over time that single force broke, it differentiated; and something similar happens in the human body as we develop from a single cell; we differentiate, different tissues form in our bodies, different layers of tissues.

Using cultured cells derived from human tumors of the breast and prostate gland, they confirmed that the IL6R / STAT3 / miR -34 a feedback loop is also activated in other tumor types.

Embryonic stem (ES) cells, harvested from three - and - a-half-day-old mouse embryos or five - and - a-half-day-old human embryos, are referred to as pluripotent because they can become any of the thousands of cell types in the body.

During embryonic development, organ - specific cell types are formed from pluripotent stem cells, which can differentiate into all cell types of the human body.

They tried hundreds of different recipes; eventually they discovered that if they mixed liver precursor cells (derived from iPS cells) with two other types of standard human cell lines known to be important for embryonic liver development, then the cells would spontaneously form a 4 to 5 - millimeter 3D structure called a liver bud.

«Massive single - cell survey of kidney cell types reveals new paths to disease: Study of over 57,000 cells from mouse kidneys help identify human renal disorders.»

The study provides new details of how, billions of years ago, complex cell types that comprise plants, fungi, but also animals and humans, gradually evolved from simpler microbial ancestors.

Sergey Nikolaev from the UNIGE Faculty of Medicine focused on Basal Cell Carcinoma (BCC), a type of cancer that is very common in humans.

Earlier this year, scientists at University of California, Los Angeles, and Advanced Cell Technology of Marlborough, Massachusetts, reported in The Lancet about the safe and successful use of RPE cells derived from human embryonic stem cells, rather than iPS cells, to treat a different type of AMD in a limited number of human patients.

Phages, shown here surrounding and attacking a bacterial cell, are part of a newly discovered type of immunity that protects mucus - covered human tissue from bacterial infection.

To determine whether ZFN - mediated disruption of cxcr4 indeed protects CD4 + T cells from an in vitro HIV challenge, human CD4 + T cells from three different ccr5 wild type donors were stimulated and transduced with AdX4 - ZFNs or an AdR5 - ZFNs control.

Furthermore, they integrated single - cell datasets of pancreatic tissue from humans and mice, thereby identifying 10 cell types that were shared across species and defining the evolutionary changes occurring in each group.

The bacteria hide within human cells called macrophages, escaping the body's own immune defenses and being shielded from many types of antibiotics.

It will further discuss efforts to capture distinct stem cell types and states from the preimplantation embryo including naïve human embryonic stem cells.

SAN FRANCISCO, CA — Scientists at the Gladstone Institutes created a special type of neuron from human stem cells that could potentially repair spinal cord injuries.

For the time course study, cells were treated with 20 μM of EGCG for 12, 24, 48, 72, or 144 h. Human colon cancer cell line HT - 29 and prostate cancer cell line PC3 were obtained from American Type Culture Collection (Manassas, VA), and were grown in McCoy's 5A and RPMI 1640 containing 10 % fetal bovine serum, respectively.

These cells have two main properties, unlimited self - renewal that can produce laboratory any desired number of undifferentiated cells and pluripotency, which provides access from the undifferentiated cells in all cell types of the human organism.