Sentences with phrase «human cells and tissue»

Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center — the nucleus — appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.

These results were also confirmed on human cells and tissue samples.

In this study, the researchers took a two - pronged approach, using human cells and tissue.

It's essentially the same process used in medicine to cultivate human cells and tissues.

The group also reported — and I guess I'm burying the sci - fi lede here — growing human cells and tissues in pig and cattle embryos.

An analysis of the HPV16 genome from 5,570 human cell and tissue samples revealed that the virus actually consists of thousands of unique genomes, such that infected women living in the same region often have different HPV16 sequences and variable risks to cancer.

«One of the broader goals of our research is to make regenerative treatments more accessible and clinically relevant by developing easy, efficient and cost - effective ways to engineer human cells and tissues,» said Shyni Varghese, a bioengineering professor at UC San Diego and senior author of the study.

Proteomics researchers in Sweden plan to release a database next week containing hundreds of thousands of images of where different proteins are located in human cells and tissues.

Our lab investigates the mechanisms by which this complex and similar groups of proteins organize DNA and regulate transcription in human cells and tissues, as well as in the model organism of Drosophila melanogaster.

We have collaborated nationally and internationally with colleagues to develop improved humanized mouse models and optimize the technologies used for engraftment of normal and malignant human cells and tissues.

We have developed SCID mouse models that support high levels of engraftment with human cells and tissues to overcome these limitations.

Each of Emulate's proprietary Organ - Chips — such as the lung, liver, brain, intestine or kidney — contains tiny hollow channels lined with tens of thousands of living human cells and tissues, and is approximately the size of an AA battery.

Organ - Chips — such as the lung, liver, brain or kidney — are micro-engineered environments lined with living human cells and tissues.

He's gotten great results, elucidating the idea that fasting causes human cells and tissues to enter «survival mode» which allowed them to survive the withering effects of cancer treatment.

Not exact matches

ReInnervate, a start - up in Durham, England, is developing a tiny, three - dimensional plastic scaffolding on which human cells can be grown into artificial tissue, and perhaps eventually into replacements for organs.

For example, using 3 - D bioprinters — which can print the structure of human tissue with biodegradable material — and stem cells, which are used to populate the 3 - D printed structure, researchers can grow actually human tissue.

A research group at Cincinnati Children's Hospital Medical Center used human pluripotent stem cells (hPSCs) to grow human stomach tissue (paywall)-- and, notably, the part of the organ that produces digestive enzymes.

In a rare appearance Dr. Chandan Sen, Director, OSU Center for Regenerative Medicine & Cell - Based Therapies will explain how this breakthrough came about and how the technology is leading to other medical discoveries and how the principle can be used to generate any tissue out of skin or fat which is abundant in human body.

The difficulties associated with obtaining nerve tissue at the correct stage of development and differentiation from aborted embryos means that foetal tissue transplantation is no longer in favour, but the creation of human embryos specifically as sources of stem cells, and the push to use «spare» embryos from IVF treatments is gatheringmomentum.

The building block electronic and protonic actual occasions are, in the case of human beings, swept into vastly more complex, Chinese box - like sets of containing societies within which there are social levels that can be identified with cells, others which answer to Aristotle's levels of tissues and organs, and which finally are presided over by what Whitehead refers to as the regnant nexus, a social thread of complex temporal inheritance which, Whitehead suggests, wanders from part to part of the brain, is the seat of conscious direction of the organism as a whole, and answers to what in Plato and Aristotle is called the soul.

Pro-choice euphemisms like «pre-embryo,» «foetal tissue,» and «ball of cells» are materialistic and reflect fully the diminishment of human life as chance — easy come, easy go.

StemExpress describes itself as «a multi-million dollar company that supplies human blood, tissue products, primary cells and other clinical specimens to biomedical researchers,» according to the company website.

Whilst acknowledging that many questions remain unanswered in the debate between those who would advocate the use of stem cells taken from human embryos, and those experimenting on stem cells drawn from tissues of the adult human body, there is a lengthy discussion of the moral status of the human embryo as being a crucial matter in this regard.

Coconut oil provides many benefits including the ability to regulate blood sugar and hormone levels, boost thyroid function, fuel the human body's metabolic demands and provide healing support to cells, tissue and organs.

Malfunctioning mitochondria can cause problems in every cell in the body, contributing massive stress to our internal environment, increasing inflammation, rapid breakdown of tissues, and eventually degeneration of the human body (AKA rapid aging).

As well as allowing the use of stem cells grown from established cell lines, the technology could enable the creation of improved human tissue models for drug testing and potentially even purpose - built replacement organs.

But scientists published in Cell Reports that they've discovered a way to regenerate those cells in mouse, primate and human tissue samples.

On Thursday, the United Nations» member states will consider two resolutions: One resolution would ban all human cloning methods, including efforts to use cloned embryonic stem cells to try and generate healthy tissues, or to treat degenerative diseases such as Parkinson's.

Da Cruz and his team grew replacement RPE cells from human embryonic stem cells on a thin plastic scaffold, before transplanting the tissue into the back of each volunteer's eye.

Philippe Durand and Marie - Hélène Perrard at the biotechnology company Kallistem in Lyon, France, say that their method coaxes seminiferous tubules — tissue that produces sperm in the testes — taken from humans, rats or monkeys into producing mature sperm cells.

Scientists are forced either to experiment on whole animals, which is expensive, raises ethical issues and may not predict effects in humans, or to perform tests on microscopic human cells found in tissue cultures, which have been altered to live forever and bear little relation to actual living, breathing people.

Researchers there are examining the role of other signaling factory beyond BMP as well as conducting further studies using human cells and human scar tissue.

In cancer research, our goal is to be able to start with a sample of human tissue, extract many cells of interest, and perform genetic analysis upon each of them separately.

The biobank of MedUni Vienna and Vienna General Hospital is a central service facility dedicated to the storage of human tissue, cell material and body fluids for more in - depth diagnosis, academic research projects and clinical tests, as well as working - up samples by way of a medical service.

But the latter approach is currently unethical to attempt in humans, and the former faces many obstacles in delivering treated cells back to muscle tissues.

RNAScope ISH was developed by Advanced Cell Diagnostics (ACD) Inc., initially for studies of gene expression in animal (and especially human) tissues.

The researchers have compared various processes involved in gene expression, such as gene transcription and chromatin modification, and have repeated this in different tissues and cell types from both humans and mice.

Some of the leading non-animal tests are conducted on cell cultures, human and animal corneas from eye banks, corneal tissue cultures, and frozen corneas supplied by hospitals.

Abba Zubair, M.D., Ph.D, believes that cells grown in the International Space Station (ISS) could help patients recover from a stroke, and that it may even be possible to generate human tissues and organs in space.

These techniques include: human tissue created by reprogramming cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where human tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.

The result was the largest deletion ever observed in the dystrophin gene using CRISPR / Cas9, and the study was the first to create corrected human iPS cells that could directly restore functional muscle tissue affected by Duchenne.

The «target» cells on the other side of the BeWo barrier to the nanoparticles were human fibroblast cells, found in skin and connective tissue.

Sen and his colleagues tested sucralose, a popular low - calorie sweetener, on stem cells — cells that could change into mature fat, muscle, cartilage or bone cells — taken from human fat tissue.

As it can take weeks to grow human cells into intact differentiated and functional tissues within Organ Chips, such as those that mimic the lung and intestine, and researchers seek to understand how drugs, toxins or other perturbations alter tissue structure and function, the team at the Wyss Institute for Biologically Inspired Engineering led by Donald Ingber has been searching for ways to non-invasively monitor the health and maturity of cells cultured within these microfluidic devices over extended times.

In 2008 the National Institutes of Health launched the $ 190 - million Roadmap Epigenomics Project with the goal of cataloguing the epigenetic marks in the major human cell types and tissues.

Researchers at the University of California San Diego have discovered an easy and efficient way to coax human pluripotent stem cells to regenerate bone tissue — by feeding them adenosine, a naturally occurring molecule in the body.

Now, many research advocates are wondering how Price's mix of views might play out in the new administration's approach to a wide range of issues, including funding, research involving human embryonic stem cells and fetal tissue, and the appointment of a new NIH director.

In humans, the goal of SCNT is «nonreproductive cloning» — making embryos, then removing stem cells from the embryo and cultivating them to grow into tissues that could cure diseases, replace organs and heal injuries.

To fully realize the field's clinical potential, the tissue engineers of the future must possess «a broad understanding of basic sciences (including biology, chemistry, and physics) and a sophisticated understanding of human pathophysiology, stem cell biology, and tissue mechanics.»

In rats and tissue cultures of human nerve cells, these «beta sheet breakers» not only prevent amyloid plaques from forming, but also dissolve existing plaques.