While working with Jung at Harvard, she identified a novel molecular mechanism through which a protein in
human cells called RIG - I mediates defense against viruses.
The bacteria hide within
human cells called macrophages, escaping the body's own immune defenses and being shielded from many types of antibiotics.
The Discher Lab has since shown that a protein on
human cells called CD47 functions as a «marker of self» by interacting with a protein on the surface of macrophages called SIRPA.
Not exact matches
But in the lab, when the scientists manipulated
human cells to be able to create the water bear shielding protein —
called Dsup — they showed about half the DNA damage as normal
cells.
Hoping to learn something about how the
human body defends itself against cancer, he had zeroed in on a complex regiment of lymphocytes
called T
cells, common to the immune systems in both mouse and man.
But since you and I both know God is the ultimate authority and thus sets the standard, and God clearly is against abortion, and the atheists are erroneously
calling very early
human life nothing but «a bunch of
cells,» isn't it up to us to fight for those lives?
A few weeks ago we all heard the announcement of a major scientific breakthrough that allowed scientists to create the equivalent of
human embryonic stem
cells (
called induced pluripotent stem
cells) but without using or destroying embryos.
Evidence of the fact that union differentiates is to be seen all round us — in the bodies of all higher forms of life, in which the
cells become almost infinitely complicated according to the variety of tasks they have to perform; in animal associations, where the individual «polymerises» itself, one might say, according to the function it is
called upon to fulfil; in
human societies, where the growth of specialization becomes ever more intense; and in the field of personal relationships, where friends and lovers can only discover all that is in their minds and hearts by communicating them to one another.
Examples are 9/11 hijackings, The holding back of stem
cell research that could save countless
human lives, Aids being spread due to religious opposition to the use of condoms, Christians legally fighting this year to teach over 1 million young girls in America that they must always be obedient to men, the eroding of child protection laws in America by Christians, for so
called faith based healing alternatives that place children's health and safety at risk, burning of witches, the crusades, The Nazi belief that the Aryans were god's chosen to rule the world, etc... But who cares about evidence in the real world when we have our imaginations and delusions about gods with no evidence of them existing.
The building block electronic and protonic actual occasions are, in the case of
human beings, swept into vastly more complex, Chinese box - like sets of containing societies within which there are social levels that can be identified with
cells, others which answer to Aristotle's levels of tissues and organs, and which finally are presided over by what Whitehead refers to as the regnant nexus, a social thread of complex temporal inheritance which, Whitehead suggests, wanders from part to part of the brain, is the seat of conscious direction of the organism as a whole, and answers to what in Plato and Aristotle is
called the soul.
We referred to the news that these
cells,
called induced pluripotent stem
cells (iPSCs), could be made from
human skin....
There are no substances because the organized entities
called atoms,
cells,
human beings and the like do not remain unchanged, no matter what their environment.
The lab - grown meat — which the company
calls «clean meat» — is developed from self - reproducing
cells taken from a chicken, with the purpose of creating a product that omnivores can't distinguish from the real thing, but with a fraction of the considerable downsides of meat production, including environmental destruction and using agricultural land to grow animal feed rather than crops for
human consumption.
Capsaicin only inflames
human cells because heat - detecting proteins in our nerve endings
called TRPV1 receptors become activated in the chemical's presence, mistakenly interpreting capsaicin as a sign of extreme heat, and sending the body's burn defenses into overdrive.
Scientists at the Johns Hopkins Kimmel Cancer Center say they have preliminary evidence in laboratory - grown,
human airway
cells that a condensed form of cigarette smoke triggers so -
called «epigenetic» changes in the
cells consistent with the earliest steps toward lung cancer development.
This study built on previous research from the Sundrud lab, which showed that when TH17
cells entered the intestine in
human tissue samples, they increased the expression of a gene
called MDR1.
Introducing
human prostate cancer
cell lines into mice, Wu and his colleagues saw a particular enzyme
called MAOA activate a cascade of signals that made it easier for tumor
cells to invade and grow in bone.
Shukla and colleagues discovered that a small drug molecule
called BX795, which is sold to labs for use in experiments, helped clear HSV - 1 infection in cultured
human corneal
cells, in donated
human corneas, and in the corneas of mice infected with HSV - 1.
The main cog in the
human biological clock is the suprachiasmatic nucleus (SCN), a group of nerve
cells in a region at the base of the brain
called the hypothalamus.
These «organs on a chip,» as they are
called, are typically glass slides coated with
human cells that have been configured to mimic a particular tissue or interface between tissues.
Oliver Brüstle, director of the Institute of Reconstructive Neurobiology at the University of Bonn, Germany, who had a patent on a method for generating neurons from
human embryonic stem
cells rejected by the court,
called the ruling «the worst possible outcome», and «a disaster for Europe».
BRAIN CANDY A new database offers a deep look at living
human nerve
cells, revealing elaborate branching structures and myriad shapes, such as in this neuron
called a pyramidal
cell (
cell image, left and 3 - D computer reconstruction, right).
In
humans, Huntington's is an inherited disease caused by a gene encoding a toxic protein,
called mutant huntingtin, which causes brain
cells to die.
A research team led by scientists from Brigham and Women's Hospital has developed a novel technology platform that enables the continuous and automated monitoring of so -
called «organs - on - chips» — tiny devices that incorporate living
cells to mimic the biology of bona fide
human organs.
Some scientists study
cells,
called primary
human trophoblasts, that are isolated from placentas obtained after childbirth, but such
cells do not divide, can be more difficult to obtain, and are more difficult to genetically manipulate to learn about biochemical pathways that have a role in placental function, Dr. Coyne said.
The unaltered hemagglutinin is akin to a key that unlocks a so -
called receptor molecule in
cells lining the upper airways of
humans and other mammals.
We use viruses
called phages that infect bacteria but not
human cells.
Vamsi Mootha, a mitochondrial biologist at Massachusetts General Hospital, his graduate student Isha Jain, and their colleagues used a popular DNA - editing tool
called CRISPR to knock out about 18,000 different genes in
human cells that were altered to have the same problems as people with mitochondrial diseases.
Two weeks after the experimental myocardial infarctions, the Seattle researchers injected 1 billion heart muscle
cells derived from
human embryonic stem
cells,
called human embryonic stem
cell - derived cardiomyocytes, into the infarcted muscle.
Published in Molecular Neurobiology, the study led by Dr Elodie Siney under the supervision of Dr Sandrine Willaime - Morawek, Lecturer in Stem
Cells and Brain Repair at the University, analysed how enzymes called ADAMs affect the movement and function of the human tumor c
Cells and Brain Repair at the University, analysed how enzymes
called ADAMs affect the movement and function of the
human tumor
cellscells.
Several studies have supported a role for cancer stem
cells in the aggressive brain tumors
called glioblastoma, but those studies involved inducing
human tumors to grow in mice, and as such their relevance to cancer in
humans has been questioned.
They added the modified adrenaline compound,
called CP - 331679, to cultured
human fat
cells, and saw that the receptors were activated and were triggering a biochemical cascade inside the
cell.
Geron, the biotech wunderkind, last made big news in November 1998 when scientists they funded — James A. Thomson of the University of Wisconsin and John D. Gearhart of Johns Hopkins — independently isolated two sorts of so -
called human pluripotent stem
cells.
In
humans, a comparison of bone marrow from 14 normal bone marrow donors, 35 multiple myeloma patients and 11 patients with a noncancerous condition
called monoclonal gammopathy of undetermined significance (MGUS) showed that Runx2 levels were significantly higher in the multiple myeloma
cells.
He determined that a compound produced by the mold, which he
called penicillin, could kill pathogenic bacteria but not white blood
cells or
human tissue.
The
human version of the
cells,
called region - selective pluripotent stem
cells, or rsPSCs, can also grow inside a mouse, something other
human stem
cells can't do, says Jun Wu, a research associate involved in the work, published in May in Nature.
The
calling patterns of three million
cell phone users support a theory that female relationships change with shifting biological priorities, suggesting that women drive the evolutionary fitness of
humans
The mice benefited from
human stem
cells called glial progenitors, immature
cells poised to become astrocytes and other glia
cells, the supposed support
cells of the brain.
Experimenting with
human cells and mice, Johns Hopkins researchers have found that a genetic mutation that alters a protein
called NOD1 may increase susceptibility to
human cytomegalovirus (CMV) infection.
The team found that lithium delays aging by blocking GSK - 3 and activating another molecule
called NRF - 2, which is found in worms, flies and mammals (including
humans) and is important for defending
cells against damage.
Knowledge of this structure,
called the cytoplasmic tail of gp41 protein, will help researchers further understand how the virus infects
human cells and how progeny viruses are assembled and released from infected
cells.
Human cells contain a protein
called SQR that was thought to detoxify sulfur, but Mitchell's data indicate that it may allow
cells to switch to hydrogen sulfide for energy production when oxygen isn't around.
Certain blood manipulation methods, such as administration of recombinant
human erythropoietin (rHuEPO) and homologous blood transfusion, are currently tracked through a longitudinal profile
called the athlete biological passport (ABP); however, there is not yet a test available for ABT, which is reinfusion of the athlete's own blood or red
cell concentrates.
A company
called Hematech is already breeding genetically engineered cattle (derived from cloned stem
cells) that produce
human antibodies to fight bacterial infections, and the animals» welfare is not compromised in any way.
Losing a genetic switch that increases production of a protein
called GDF6 may have created the big toe and helped shape the
human foot for bipedalism, scientists propose in a paper published online January 7 in
Cell.
The UC team first reported how to use CRISPR in pieces of circular DNA
called plasmids that can invade bacteria, but the Broad won a race to apply the method to
human cells, which represents a potential billion - dollar marketplace for medicines.
They already knew of one such compound, a chemical
called PD09859 that is one of 60,000 agents the NCI had screened for ability to block growth of
human tumor
cells.
Although that marker,
called IL21, had not previously been associated with autoimmune diseases, the gene that produces it sits right in the stretch of DNA known to make these mice vulnerable to diabetes, suggesting that IL21 might make a drug target, says Sarvetnick.Furthermore, by giving the animals a shot of dead bacteria — similar to an immunization in
humans — when they were newborns, Sarvetnick and her colleagues prevented a surfeit of CD4 + and CD8 +
cells.
As Nature detailed last week, one Italian science agency recently sent out a
call for stem
cell grant proposals but specifically excluded
human ES
cell research, leading three Italian scientists to sue the government.
Each of these
cells,
called naive, pre-implantation embryonic
cells, has the capacity to develop into any
cell type in the
human body, an ability
called pluripotency.