Sentences with phrase «human challenge model»

Moving the Needle provides quarterly updates from PATH's Center for Vaccine Innovation and Access (CVIA) on our vaccine development efforts, as well as related supporting work, such as developing human challenge models, building capacity of developing - country vaccine manufacturers, and evaluating new adjuvants and other novel vaccine technologies.

«Seattle BioMed's Malaria Clinical Trials Center is one of only four centers in the world approved to safely and effectively test new malaria treatments and vaccines in humans by the malaria human challenge model.

The so - called «human challenge model» has a long and checkered past that began with 18th century experiments by smallpox vaccine developer Edward Jenner and later fell under intense scrutiny when they were conducted by Nazi doctors, military researchers, and academic scientists working with prisoners.

A human challenge model of dengue infection — rather than illness — is an important characteristic, explained Anna Durbin, M.D., who led the clinical trial at Johns Hopkins.

Dr. Whitehead is currently developing a human challenge model using a modified dengue serotype - 3 virus.

«We heard, «You can't treat dengue so you can't do a human challenge model,»» Durbin says.

In 2011, WRAIR and NIH sponsored a workshop to discuss «reintroducing» the human challenge model for dengue.

This is the most influential role the human challenge model has ever played in the FDA approval process.

The human challenge model has its limits, Levine stresses, noting that his group declined to participate in an experiment done elsewhere that put Neisseria gonorrhoeae in a penile catheter to study gonorrhea transmission.

The Virology Group at Cardiff University seek to recruit a Research Associate to work on a Wellcome Trust Collaborative Grant entitled: «Exploiting a human challenge model to understand the pathogenesis of cytomegalovirus».

The Virology Group, part of the College of Biomedical and Life Sciences at Cardiff University seek to recruit a Research Associate to work on a Wellcome Trust Collaborative Grant entitled: «Exploiting a human challenge model to understand the pathogenesis of cytomegalovirus».

Malaria vaccine developers have been fortunate to have access to a human challenge model — known as controlled human malaria infection or CHMI — to evaluate the protective efficacy of pre-erythrocytic vaccines in early clinical trials.