Sentences with phrase «human cholesterol metabolism»

Not exact matches

Recently, thanks to major advances in human genetics, it has become increasingly clear that not only APOE and cholesterol metabolism, but also the proper functioning of microglial cells, strongly modulates the risk of developing AD in old age.

Their discovery of the LDL receptor as the major molecule regulating cholesterol metabolism and its genetic disruption in the human disease familial hypercholesterolemia have been recognized by their receipt of numerous awards, including the Nobel Prize in Physiology or Medicine (1985), the Albert D. Lasker Award in Basic Medical Research (1985), and the U.S. National Medal of Science (1988).

A small - scale human trial published in The American Journal of Clinical Nutrition showed that when healthy men ingested a daily helping of 25 grams of gum acacia, the only effects experienced were a slight reduction in cholesterol serum and an increase in breath hydrogen, which is a marker of intestinal bacteria metabolism.