Not exact matches
The court's written
findings define an «adequate and well - controlled
human clinical study» as one lasting a minimum of six weeks using appropriate tools.
«We have now
found a potential mechanism, and at this point in our research, we need to test
human participants in a blinded, placebo controlled
clinical study — the same technique we used to
study the behavioral effects of acupuncture in rats,» says Eshkevari, a nurse anesthetist and licensed acupuncturist.
Regulatory issues must be addressed before moving to
human studies, Davies said, but the
findings published in the August issue of the Journal of
Clinical Investigation suggest that it may be possible to manipulate the bacterial residents of the gut — the gut microbiota — to treat obesity and other chronic diseases.
«While the pre-birth programming effect of PETN shows promise for future
clinical implications, we must be careful about generalizing
findings from animal
studies to
humans,» Li said.
The team used gene expression profiling and
found that canine B - cell lymphoma expression profiles were similar in many ways to
human B - cell lymphoma, thus paving the way for future
studies, including therapeutic
clinical trials in dogs and
humans.
«We
found that Asian - Americans who have the DRD2 A1 variant are more likely to crave carbohydrates and fast food than those without it,» said the
study's senior author, Dr. Zhaoping Li, director of the UCLA Center for
Human Nutrition and chief of the UCLA Division of
Clinical Nutrition.
They will test the best candidate molecules in mice to see if they can replicate their
study findings, before moving on to
human clinical trials.
«Given the alarming trend of resistance to our current antimalarial therapies, this is really an exciting
finding,» says Dr. Mota, the senior author of the
study, «and we are already working to develop Torin molecules suitable for
clinical trials of antimalarial activity in
humans.»
Studies are also underway in collaboration with the Mayo Clinic in Rochester, Minn., to test the
clinical relevance of these
findings in
humans.
The
findings discovered in animal models are translated into preclinical mechanism - driven prevention
studies that will ultimately inform epidemiologic
studies and lead to
clinical trials in
humans.
Findings from basic research, such as
studies of cancer cells in the laboratory, can ultimately define research questions to
study in
humans, such as helping to identify drugs to test in
clinical trials.
Research in animals is an important step in developing any new treatment, but we'll need to see the
findings translated into
clinical studies in people before we could know the potential of EPPS to treat Alzheimer's in
humans.
We've been able to bridge those
findings to
human studies, developing ways to both look for those neurons in the retina, see whether or not they're sick using imaging techniques that Alf and Vivek have developed, and
clinical tests along with Jeff Goldberg in order to detect whether or not patients are losing an excessive amount of those kinds of neurons by virtue of different types of field testing.
Similar to our animal
studies, we
found that JQ1 was also effective in
human heart cells, reaffirming the
clinical relevance of our results.»
The closest I've
found to a
human clinical trial of beans on intestinal permeability is this
study, which
found a Chinese medicinal gruel of Job's tears, oat, buckwheat, white bean, yellow corn, red bean, soybean, yam, big jujube, peanut, lotus seed, and wolfberry changed gut microbiota, improved gut permeability, lowered endotoxemia, and improved inflammation markers.
However, most
human studies fail to
find any
clinical benefits for giving glutamine to patients with Crohn's disease.
When it comes to
human trials, a
clinical study on 44 male smokers with lesions in the colon
found that the subjects who took 4 grams of curcumin per day for 30 days reduced their number of lesions by 40 %.
Studies have
found that astragalus has antiviral properties and stimulates the immune system, although there have been no
clinical trials examining the effectiveness of astragalus against colds in
humans.
Clinical studies of glucosamine hydrochloride (glucosamine) and sodium chondroitin sulfate in
humans found that, except for a subgroup of participants with moderate - to - severe pain, they had no better effect on joint health or pain than placebos.