Sentences with phrase «human colon»

These amazing results were also supported in test tube experiments where it was seen in human colon cells to activate a protective antioxidant response.

Normal human colon cells, kidney cells, lung cancer cells and two strains of colon cancer cells didn't respond to the bacteria.

Then, they placed human colon cells in each device.

Once formed, many of these experimental tumors spread to the liver, just like human colon cancers often do.

«In the study, using human colon cancer cell lines, we showed that the growth of cancer cells can be largely prevented using a combination of both drugs in a petri dish as well as in mouse models,» said Srivastava.

Basu and his colleagues conducted this study using an animal model of human colon tumors transplanted into mice and a mouse model of lung cancer.

In vitro experiments used human colon carcinoma cells with and without MMP9 and mouse embryonic fibroblasts, which are connective tissue cells that make the extracellular matrix and collagen and play an important role in tissue repair.

The researchers, who reported their findings in a recent issue of BMC Complementary and Alternative Medicine, suggest that the findings could pave the way for clinical testing of the compounds on human colon cancer, which is the second most common cancer in women and the third in men.

The new study, which was in collaboration with the UK Medical Research Council and Cambridge University, looked at the effect of normal supplemental doses of these compounds on two types of cultured human colon cancer cells.

Immunohistochemical of paraffin - embedded human colon using 60008 -1-Ig (ACTB antibody) at dilution of 1:50 (under 10x lens)

«In one of the less appetizing but more brilliant experiments in the field of vitamin b12 metabolism in the 50's, Sheila Callender (7) in England delineated that human colon bacteria makes large amounts of vitamin B - 12.

This led the authors to the hypothesis that molecular signals regulating SATB2 in frogs and mice could be used to make human colon organoids that express the protein.

To address this question, the research teams from Berlin and Würzburg took a closer look at human colon carcinoma cell lines that innately show high levels of c - MYC.

Next, the researchers transplanted metastasizing human colon cancer cells into a different set of mice.

In one set of experiments, they injected it into 20 mice with human colon cancers.

Soon after, a study with Bert Vogelstein at Johns Hopkins University in Baltimore, Maryland, showed that TCF - 4 also helps initiate human colon cancer.

The engineered colon secreted proteins found in natural human colon.

During observation and analysis of the now in vivo organoids, study authors looked for signs of posterior region enteroendocrine cells, which make hormones found in naturally developed human colon.

«Lab - grown human colons change study of GI disease: Stem cell derived organoids fill gap in modeling common ailments.»

Researchers report the posterior HOX helps control the formation of SATB2 - expressing human colon organoids.

The study is believed to be the first time human colon organoids have been successfully tissue engineered in this manner, according to researchers at Cincinnati Children's Hospital Medical Center who led the project.

For the time course study, cells were treated with 20 μM of EGCG for 12, 24, 48, 72, or 144 h. Human colon cancer cell line HT - 29 and prostate cancer cell line PC3 were obtained from American Type Culture Collection (Manassas, VA), and were grown in McCoy's 5A and RPMI 1640 containing 10 % fetal bovine serum, respectively.

IHC image of ab7291 staining alpha Tubulin in human colon formalin fixed paraffin embedded tissue sections *, performed on a Leica Bond.

In a recent study published in Journal of Agricultural and Food Chemistry, acai suppressed the growth and reproduction of human colon cancer cells by an astonishing 90 percent.

When the team blocked the activity of L1CAM in cultured human colon cancer cells, the cells» growth slowed dramatically.

Immunohistochemical of paraffin - embedded human colon cancer using 11176 -1-AP (HNRNPA1 antibody) at dilution of 1:100 (under 10x lens)

Human colon carcinoma cells that overexpressed MMP9 showed decreased cell proliferation, less DNA damage and cell cycle arrest in the S - phase to prevent cell proliferation.

Nakamura Y, Yogosawa S, Izutani Y et al.. A combination of indol -3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT - 29 cells by inhibiting Akt phosphorylation and progression of autophagy.

Munera, study first author, pointed to a number of new ways that human colon organoids could be used study disease.

Using human colon cancer cells and primary human fibroblasts isolated from tumors and adjacent normal tissues, Alexandros Glentis and colleagues at the Institut Curie addressed the question of whether the cancer cells or the CAF cells were responsible for the breakdown of the basement membrane that leads to cancer progression.

A flavorful component of cinnamon oil, called cinnamaldehyde, may help prevent colon cancer, according to a tissue culture study of human colon cancer cells published in the May 2010 issue of the journal «Molecules.»

Over 100 different oligosaccharides have been identified in the human colon, and recent research has shown that variations in the oligosaccharides within the mucus are associated with variations in the composition of the gut microbiota.

The researchers concluded that using collagen - based membranes in organ - on - a-chip devices enhance the growth, viability and barrier function of human colon cells and that the method likely could be extended to cells from other organs.

An image of tissue from a human colon uses fluorescent staining to show the presence of the protein alpha - synuclein (red) inside gut endocrine cells (green).

In a previously published study by Gruev, a bioinspired polarization sensor fitted to a colonoscope could detect the disordered nature of cancerous cells in the human colon.

Like other parts of the GI tract grown by the researchers, the human colon organoids also create a potential new platform for testing new drugs before the start of clinical trials.

This confocal microscopic image shows a human colon organoid generated in the laboratory with human pluripotent stem cells.

Researchers report that following transplant, the human colonic organoids assumed the form, different structures and molecular and cell properties of the human colon.

To develop a model for generating the human colon, scientists first identified SATB2 (special AT - rich sequence - binding protein 2) as a definitive molecular marker for hindgut in frogs, mice and in humans.