Sentences with phrase «human controlled trials»

The effects of avocado on some of these risk factors has been studied in 8 human controlled trials.

However, this needs to be studied properly in human controlled trials before any recommendations can be made.

However, this needs to be studied properly in human controlled trials before any recommendations can be made.

Not exact matches

«There are no randomized, controlled trials in human beings that show that these nootropics have any benefits above and beyond what we would see if someone were to follow a healthy diet and maintain regular exercise,» Dr. Tsourounis says, adding, «You should always talk to your doctor or health - care provider before starting any supplement or any medicine.»

The Functional Food Centre of Oxford Brookes University conducted a trial using Aduna Baobab Powder and found that human participants who consumed a milk containing baobab had a lower blood glucose response than those who had a control drink with no baobab.

Now that they've demonstrated the significance of insulin signaling in the human mammary gland, they are planning a phase I / II clinical trial with a drug used to control blood sugar in type 2 diabetes to determine whether it improves insulin action in the mammary gland, thus improving milk supply.

Judges found control orders placed on six Iraqis breached Article 5 of the Human Rights Act by imposing indefinite detention without trial.

CALERIE (Comprehensive Assessment of the Long - Term Effects of Reducing Intake of Energy) was the first randomized controlled trial to test the metabolic effects of calorie restriction in non-obese humans.

When the researchers gave concentrated broccoli sprout extracts to 97 human type 2 diabetes patients in a 12 - week randomized placebo - controlled trial, obese participants who entered the study with dysregulated disease demonstrated significantly decreased fasting blood glucose levels compared to controls.

Clinical research focuses on interventional human trials to evaluate drugs and treatments in a controlled setting.

«Next steps are to further explore this possibility in human trials in order to assess if it will help patients, but these two drugs make sense from a variety of studies and we find that they act together through multiple mechanisms to control cancer growth in the laboratory.»

«And now we have literally dozens and dozens of randomized controlled trials across a range of conditions in low - resource settings using low - cost human resources,» he says, «and they're backed by economic data of the cost effectiveness of these interventions.»

The placebo - controlled trial in nearly 9500 women tested a gel called PRO 2000, a so - called polyanion that prevented the AIDS virus from entering human cells in test - tube and monkey studies.

It is the first and largest phase III randomized controlled trial of stable, synthetic human angiotensin II.

Further research will be needed to adapt the technique for humans, but the approach could offer improved safety and efficacy control for human clinical trials, which are now underway in Canada.

This is the first study in human trials to identify genes driving acute peanut allergic reactions using a double - blind placebo - controlled approach with comprehensive sequencing of genes expressed before, during, and after they ingested peanut.

«We are exploring alternative directions for developing this compound, including potential use of the animal efficacy rule,» Cihlar said, referring to a regulatory mechanism under which the U.S. Food and Drug Administration may consider efficacy findings from adequate and well - controlled animal studies of a drug in cases where it is not feasible or ethical to conduct human trials.

At Massachusetts General Hospital doctors have started clinical trials on human volunteers to test brain implants that give paralyzed people the ability to control a computer cursor with thought alone.

This led to initiate an overseas, randomized controlled registered phase I / II trial in humans including 70 chronic SCI patients.

iBET's infrastructure comprises 16 laboratories fully equipped with state - of - the - art technology (70 m2 each), including a BSL2 laboratory for working with viruses; a GMP Analytical Services Unit certified by the INFARMED (the Portuguese medicines authority, EMA Portuguese branch) and by DGAV (the Portuguese veterinary authority) for quality control and batch release of human and veterinary pharmaceuticals, biopharmaceuticals as well as experimental new drugs; a GMP Mass - Spectroscopy Unit that provides state - of - the - art MS services to the scientific community and Industry; a 2600 m2 bio-pilot plant supporting production and purification of proteins ATMPs and vaccines from bench top to 300 L scale and privileged access to GeniBET Biopharmaceuticals, an iBET spin - off producing ATMPs under cGMP certification for phase I / II / III clinical trials.

In their first - in - human, double - blind, placebo - controlled Phase I trial, Prothena scientists recruited 40 healthy people without PD to receive either placebo injections or or one of 5 doses of PRX002, ranging from 1 to 30 mg / kg.

P27A can proceed to a controlled human malaria infection phase IIa clinical trial when additional funding is available.

It wasn't a single clinical trial but rather a review article that looked at the results of more than 140 randomized and controlled human clinical trials — the research gold - standard — published between 1950 and 2007.

It wasn't a single clinical trial, but rather, a review article that looked at the results of over 140 randomized, controlled, human clinical trials — the research gold - standard — published between 1950 and 2007.

While there have been a number of human clinical studies, we need larger, randomized, properly - controlled clinical trials that look specifically at these suspects.

According to a study published in International Journal of Sport Nutrition and Exercise Metabolism, reporting on the research from a blind experiment involving placebo controlled human trial, the daily intake of 500 mg of Grecunin extract during the course of eight weeks, greatly lowered the levels of body fat and estradiol in resistance training individuals, and at the same time it increased the total lean body mass and the levels of available testosterone.

Table 1: Summary of Randomized Controlled Trials in Human Populations Looking at the Effects of IER on Indices of Cardiometabolic Health (Click image for larger view)

That's understandable, given that health major undergrads putting together a thesis rarely have access to the funding necessary for human randomized controlled trials.

Many of the studies are so - called randomized controlled trials, the gold standard of scientific experimentation in humans.

Ten years ago, there was not much scientific evidence behind the low - carbohydrate diet, however since 2003, there have been over 27 randomized, controlled, scientific human trials.

Human clinical trials support the role of chlorogenic acid - rich green coffee bean extract in promoting healthy blood sugar control and reducing disease risk.

Randomized controlled trials conducted with humans are the gold standard of supplement research.

Most human trials are not carried out long enough to detect any increase in cancer rates, but in one trial, breast cancer rates of those taking a statin were 1500 percent higher than those of controls.

Because intermittent fasting and CR have not been conclusively proven to have beneficial effects in humans with acceptable safety profiles (1), they were not considered to be controls for trials that were identified.

Whereas enthusiasm for fasting is increasing, clinical relevance remains low because of insufficient human data, including almost nonexistent controlled trials (21, 33 — 36), few clinical outcomes studies (37, 38), lack of correction for inflated type I error rates from multiple hypothesis tests, and limited safety data (39 — 41).

Most human fasting interventional trials have been for the primary endpoint of weight loss and have not used control arms (some used multiple noncontrol energy - restriction regimens).

Results: Three randomized controlled clinical trials of fasting in humans were identified, and the results were published in 5 articles, all of which evaluated the effects of fasting on surrogate outcomes.

Filters were also used for «humans» to eliminate animal studies and — for aim 1 — «clinical trial» to eliminate clinical studies that did not have a control arm.

Whereas the few randomized controlled trials and observational clinical outcomes studies support the existence of a health benefit from fasting, substantial further research in humans is needed before the use of fasting as a health intervention can be recommended.

The study was well designed; it was a double blind, placebo controlled trial on humans, which is the gold standard of scientific research.

Key Features: Controls bad breath with delmopinol, an ingredient used for years in human oral rinses Clinically proven to reduces plaque and calculus in dogs in more than 3 dozen rigorous human and animal clinical trials Low - calorie formula does not negatively impact your dog's body weight or eating habits Block plaque, calculus, and halitosis with the science of prevention.

A recent review of 50 randomized controlled human trials or studies reporting use of nutritional supplements with chemotherapy / radiation showed that the patients that took antioxidants and other nutrients had an increased survival rate compared to those that did not.

DBD is a 4v1 asymmetrical multiplayer horror game in which four human - controlled survivors must fix generators to escape a «trial», while outwitting one human - controlled killer.

In addition, it was held that it was not inconsistent with the general rule stated in Art 6 (1)(the right to fair trial) of the European Convention on Human Rights for a state to designate an entire class of case as an exception when considered necessary where required by the interests of juveniles or the protection of the private life of parties, although the need for such a measure must always be subjected to the court's control.

In 1956, the first large - scale human trial of the birth control pill was carried out in Puerto Rico.