Sentences with phrase «human cytomegalovirus»

Though hailed as «a new therapeutic principle» in 1990, it nonetheless took another eight years for the FDA to approve the first antisense drug, fomivirsen — for the treatment of AIDS - related retinitis caused by human cytomegalovirus.

Human cytomegalovirus IE1 protein disrupts interleukin - 6 signaling by sequestering STAT3 in the nucleus.

Human cytomegalovirus reactivation during lactation and mother - to - child transmission in preterm infants.

Goodrum seeks to uncover the mechanisms by which human cytomegalovirus — a herpesvirus that infects many people — establishes its lifelong latent infection.

It's how HIV works, and also how viruses in the herpesvirus family, like human cytomegalovirus (HCMV), do their business.

Using this device, which attaches directly to the camera module on a smartphone, Ozcan's team was able to detect single human cytomegalovirus (HCMV) particles.

The UL144 gene product of human cytomegalovirus activates NFkappaB via a TRAF6 - dependent mechanism.

Human Cytomegalovirus Immediate - Early 1 Protein Rewires Upstream STAT3 to Downstream STAT1 Signaling Switching an IL6 - Type to an IFN?

Human cytomegalovirus major immediate early 1 protein targets host chromosomes by docking to the acidic pocket on the nucleosome surface.

Trautmann L, Rimbert M, Echasserieau K, Saulquin X, Neveu B, Dechanet J, Cerundolo V, Bonneville M. Selection of T cell clones expressing high - affinity public TCRs within Human cytomegalovirus - specific CD8 T cell responses.

6/22/2007 New Vaccine Prevents CMV Infection and Disease in Mice Researchers at the University of California, San Diego (UCSD) Skaggs School of Pharmacy and Pharmaceutical Sciences have patented a strategy for developing a human vaccine to prevent against Human Cytomegalovirus (hCMV) infection and disease.

Human cytomegalovirus IE1 protein elicits a type II interferon - like host cell response that depends on activated STAT1 but not interferon -?.

Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro.

He started his Ph.D. at the University of Cambridge in the U.K. in 1981 studying the cancer - inducing potential of human cytomegalovirus.

Dr Finn Grey, a Senior Research Fellow at the University of Edinburgh's Roslin Institute, said: «Human Cytomegalovirus infection is an important human disease.

Scientists have discovered a key molecule linked to Human Cytomegalovirus (HCMV) infection, which is harmless for healthy people but can cause miscarriage and birth defects during pregnancy.

Experimenting with human cells and mice, Johns Hopkins researchers have found that a genetic mutation that alters a protein called NOD1 may increase susceptibility to human cytomegalovirus (CMV) infection.

This aging process is accelerated by persistent viral infections, such as HIV and CMV (human cytomegalovirus).

A publication in the scientific journal Nature Microbiology identifies PDGFRα as the receptor for the trimeric gHgLgO complex of Human cytomegalovirus (HCMV).

Most healthy people barely notice infection with the human cytomegalovirus (hCMV), a form of the herpes virus that has evolved with humans over thousands of years and usually lays dormant in the body after initial infection.

The drugs dampen a certain inflammatory enzyme, which also proves essential for replication of human cytomegalovirus (CMV).

Nucleosome maps of the human cytomegalovirus genome reveal a temporal switch in chromatin organization linked to a major IE protein.

A Retro94 - based compound may prevent a common and sometimes fatal virus, human cytomegalovirus (CMV) from reproducing and protect immunocompromised patients, like those with HIV, on chemotherapy, with transplants and infants from the effects of the disease, according to Penn State College of Medicine researchers.

Each vector will constitutively express their respective therapeutic transgene (i.e. HSV1 - TK or Flt3L) under the control of the human cytomegalovirus promoter (hCMV).