Sentences with phrase «human diabetes patients»

STUDY FIVE — the worst study, conducted on human diabetes patients.

Not exact matches

The Golden Goose Award has honored innovative research that developed a diabetes medication from Gila monster venom, an algorithm based on marriage stability that led to the development of a program to match kidney patients with donors and the «marshmallow test» — a measure of young children's self - control that has led to greater understanding of human behavior.

When the researchers gave concentrated broccoli sprout extracts to 97 human type 2 diabetes patients in a 12 - week randomized placebo - controlled trial, obese participants who entered the study with dysregulated disease demonstrated significantly decreased fasting blood glucose levels compared to controls.

«Acute repeated spikes in blood sugar that you see with each dose of this drug have long - term impacts — and can predispose patients to the development of insulin - resistance Type 2 diabetes and cardiovascular disease,» said David Wright, associate professor in the Department of Human Health and Nutritional Sciences and corresponding author of the paper.

After that, human clinical trials would be required to show whether the combination of hydrogel material and protein will benefit patients with type 1 diabetes.

In addition to looking at mouse models of diabetes, the researchers also showed that exposure of human pancreatic islet cells — both from healthy donors and from patients with Type 1 diabetes — to fasting - mimicking diet in a dish stimulated insulin production.

We also reactivated insulin production in human pancreatic cells from type 1 diabetes patients.»

They've figured out how to turn human stem cells into functional pancreatic β cells — the same cells that are destroyed by the body's own immune system in type 1 diabetes patients.

In May 2005, Hwang and his colleagues reported that it had produced 11 new human embryonic stem (ES) cell lines that carried the genetic signature of patients with diabetes, spinal cord injury, or a genetic blood disorder (Science, 20 May, p. 1096).

In humans it could potentially treat Type 1 diabetes in early stage patients, during what is known as the «honeymoon period,» when the pancreatic beta cells have not been completely destroyed and continue to secrete insulin.

If replicated in humans, this effect could significantly delay, and potentially prevent, the need for chronic insulin use by Type 1 diabetes patients, and help minimize diabetes - related complications.

There is a lot of work still to do, and many potential pitfalls before it could be applied to human patients, but in principle almost any illness caused by damaged or ageing tissue — heart disease, diabetes, Alzheimer's and dozens of others — could be fixed this way.

The method, which involves inserting genetic material that makes the cells» development run backwards, opens the door to stem cells specific to patients, which could be used to repair damaged organs or fight diseases such as Parkinson's and diabetes — crucially, all without the need to destroy human embryos.

This week, he and his colleagues report a potentially significant step toward that goal: a recipe that can turn human stem cells into functional pancreatic β cells — the cells that are destroyed by the body's own immune system in type 1 diabetes patients such as Melton's son and daughter.

Millions of diabetes patients could benefit if researchers can achieve such alchemy with human cells.

Of special note today: gut microbiota species expressing orthologs of human Ro60 might be involved in triggering and sustaining chronic autoimmunity in lupus; The portal vein blood microbiome in patients with liver cirrhosis; A randomized clinical study suggests dietary promotion of short chain fatty acid producing gut microbes as an effective treatment for type 2 diabetes; and the sexual dimorphism of root, flower and leaf microbiomes in the wild strawberry plant

They then examined the effect of a chemical that inhibits SRF and found that glucose uptake rates increased in both mice and human cells — and that the effects were greater in cells from patients who were insulin resistant or had type 2 diabetes.

Transplantation of macroencapsulated human islets in patients with brittle diabetes (collaboration with Kings college, London)

These data suggest either that there are limited differences in methylation between patients with diabetes and nondiabetic subjects or that DNA methylation in human adipose tissue is highly heritable.

Human satellite cell cultures display numerous features of mature skeletal muscles (1) and have been used for studies of muscle metabolism in cultures established from patients with type 2 diabetes and healthy control subjects (1 — 5,8,9,21,22).

The Emory Transplant Center has conducted clinical trials since 2003 transplanting human pancreatic islet cells into patients with Type I diabetes.

Several clinical trials, including this one led by Emoryâ $ ™ s Nicole Turgeon, have shown that islets isolated from deceased human donors can restore normal blood sugar regulation in patients with type 1 diabetes.

Unlike in humans, oral diabetes drugs are not generally effective for feline patients, so are rarely the recommended therapy.

Epidemiological factors closely match those of human patients with the LADA form of type 1 diabetes.

The rate of progression to absolute insulin deficiency has not been studied in dogs, but epidemiological factors closely match those of human patients with the LADA form of type 1 diabetes, who are usually not obese and tend to be middle aged and older.

Type 2 diabetes also occurs most commonly in older human patients.

Gore's call to «make peace with the planet» requires an integrated awareness and action against both global warming and global warring, simultaneously — Gore describes the problem as huge, but in limiting it to civilian activities, not including military madness and mayhem, it is not huge enough — if a patient has both diabetes and severe trauma, both conditions must be treated now — militization trumps civilization in the headlines of today and tomorrow — if the truth is that both global warming everywhere and global warring anywhere are linked in the human biosphere, and if that truth is inconvenient to Mr Gore and the civilian scope of his campaign against global warming, lethal consequences for both humans and other species will continue — in cinematic terms, the great «An Inconvenient Truth» must be blended and coordinated with the great «Why We Fight»