Sentences with phrase «human disease without»

One piece of evidence is the fact that leprosy is a strict human disease without other hosts or reservoirs.

Not exact matches

The basic principle under food chemistry is to create the methods that makes it possible to harvest, preserve, process and prepare the food with high nutritional value for human consumption and increase the shelf life of food products without causing any diseases to the human.

To investigate, Walker Jackson of the Whitehead Institute in Boston, Massachusetts, and his colleagues created mice with a mutation associated with the human prion disease Fatal Familial Insomnia and injected some of their brain tissue into the brains of mice without the mutation.

Even the new studies clashed somewhat: Unlike the UCSF study, the German research found no major differences between the overall microbiomes of twins with and without MS. Finally, mouse models of MS are not perfect mimics of the human disease, and mouse immune systems aren't identical to people's.

As human cells do not contain the bd - type oxidase, the question of the ability to combat disease - causing bacteria without causing harm to the human body becomes relevant.

The human body is a habitat for a huge range of harmless and beneficial microbes, which may be the key to fighting disease without antibiotics.

The gift accompanies a paper published online today in Nature from researchers at Broad and worldwide, which identifies more than 100 areas of the human genome associated with schizophrenia, based on samples from almost 37,000 people with schizophrenia and about 113,000 without the disease.

In a study that has implications for humans with inflammatory diseases, researchers from Case Western Reserve University School of Medicine and colleagues have found that, given over a six - week period, the artificial sweetener sucralose, known by the brand name Splenda, worsens gut inflammation in mice with Crohn's - like disease, but had no substantive effect on those without the condition.

The «old friends hypothesis» proposes that the human immune system can not learn to regulate itself without exposure to common pathogens like helminths that have coevolved with people and that modern hygienic practices deprive people of this necessary exposure, possibly explaining the relatively higher and more recent prevalence of immune diseases in industrialized countries like the U.S. Loke plans to continue researching helminthic therapy in people and in monkeys.

The method, which involves inserting genetic material that makes the cells» development run backwards, opens the door to stem cells specific to patients, which could be used to repair damaged organs or fight diseases such as Parkinson's and diabetes — crucially, all without the need to destroy human embryos.

The massive project, carried out by a private company in the country, deCODE genetics, has yielded new disease risk genes, insights into human evolution, and a list of more than 1000 genes that people can apparently live without.

«We are now in a position to be able to generate patient - and disease - specific stem cells without using human eggs or embryos,» Shinya Yamanaka, leader of one of the research teams at Kyoto University in Japan, said in an e-mail interview.

Intelligent machines, having faster access to a much larger store of information and the ability to respond without human emotional biases, might also perform better than medical professionals in diagnosing diseases.

«Liver cancer is on the rise worldwide, and in human studies we've now seen that patients can progress from fatty liver disease to liver cancer without any middle steps such as cirrhosis,» says David Moore, a professor of molecular and cellular biology, who led the study with Associate Professor Loning Fu, both at Baylor.

They've found new disease risk genes, insights into human evolution — and a list of more than 1000 genes that people can apparently live without!

«If the mouse models are indicative of human disease, the combination therapy can increase the proportion of patients who respond to therapy without additional adverse side effects and can improve the quality of life for cancer patients.»

«The capability of this method to separate exosomes without altering their biological or physical characteristics potentially offers new pathways to assess human health as well as the onset and progression of diseases,» said Subra Suresh, co-corresponding author of the paper and president - designate of Nanyang Technological University Singapore, the 21st Century Professor of Biomechanics in Medicine at the University of Pittsburgh Medical School, and former president of Carnegie Mellon University.

«We are now in a position to be able to generate patient - and disease - specific stem cells, without using human eggs or embryos,» says Shinya Yamanaka of the University of Kyoto, who led the Japanese team.

The researchers found that bacteria forming part of a cluster were more likely to be taken up by human cells and to survive in them than the microbes without close relatives; the cluster strains also caused more severe disease in mice.

The IMI could also control and organize access to metadata (the associated host disease phenotype data, for a human gut microbiota sample, for instance) without which meaningful interpretation of the data is not possible.

That can make it hard to make subtle changes to a gene — like introduce point mutations corresponding to natural variations linked with human disease — without taking a sledgehammer to the entire gene locus.

Organs - on - chips allow the study of drugs and diseases without testing on animals or humans.

Dec. 18, 2017 - Lawrence Livermore National Laboratory (LLNL) scientists and engineers have developed a «brain - on - a-chip» device aimed at testing and predicting the effects of biological and chemical agents, disease or pharmaceutical drugs on the brain over time without the need for human or animal subjects.

Over the last few years, scientists have been able to recreate accurate models of human organs by embedding living tissue onto chips, allowing them to study the effects of drugs and diseases without testing on animals or humans.

For many human diseases, large - scale genomic studies have identified common genetic variants that occur more frequently in people with cardiovascular, autoimmune, inflammatory and infectious diseases, diabetes and asthma than in those without these diseases.

In a finding that supports a new mechanism of inheritance and the leading theory as to the mysterious causative agent of «mad cow» disease and human Creutzfeldt - Jakob disease, researchers at the University of Chicago's Howard Hughes Medical Institute have shown that a defective cell trait can be propagated by a faulty protein, without any DNA or RNA serving as the genetic blueprint.

A clinical trial is a research investigation when a new treatment is first given to humans, with or without a disease, to establish if the drug is safe and effective at treating the disease.

While vaccines for the disease have been developed, a permanent solution is needed for ferrets to survive in the wild without human assistance.

It should allow us to study genetic disease without having to use humans as guinea pigs, or indeed, guinea pigs as humans.»

«This approach should allow us to study genetic disease without having to use humans as guinea pigs, or indeed, Guinea Pigs as humans.

In a study that has implications for humans with inflammatory diseases, researchers from Case Western Reserve University School of Medicine and colleagues have found that, given over a six - week period, the artificial sweetener sucralose, known by the brand name Splenda, worsens gut inflammation in mice with Crohn's disease, but had no substantive effect on those without the condition.

They've been at it for a while, but scientists finally figured out how to delete disease - causing genetic code from single - celled human embryos — without any glitches — that were able to grow into disease - free multicellular embryos.

Although the assumption is often made that agriculture was in every respect an improvement upon the human condition, anthropological research shows that if our Paleolithic ancestors were able to survive accidents, infection and childbirth, their longevity was similar to that of the modern human, but without many of the chronic degenerative diseases that affect us now.

The burden of proof lies with those making the claim, particularly when said claim is contrary to how humans have eaten since (and while) we first became human (without any inflammatory disease to speak of until very recently).

In areas where there is a selenium deficiency, use of rapeseed oil has been associated with a high incidence of fibrotic lesions of the heart, called Keshan's disease.20 The animal studies carried out over the past twenty years suggest that when rapeseed oil is used in impoverished human diets, without adequately saturated fats from ghee, coconut oil or lard, then the deleterious effects are magnified.

Pets can transmit several diseases to humans without even realising.

As the hormones are known to be present in hair, at least in humans, Ouschan reasoned that measuring glucocorticoid concentrations in dog hair might represent a way of diagnosing Cushing's disease without causing the animals unnecessary distress.

However, every time a pet travels internationally without proper prior veterinary care and treatment, it is another chance for diseases that can impact both human and animal health to establish themselves in a new area.

Even in the unlikely event that a feral cat develops rabies, it can't spread the disease to people without biting them, and feral cats rarely seek direct contact with humans.

Trap - Neuter - Return programs give feral cats who can not be adopted a chance to live out their lives without posing a disease risk to humans.

It is much more humane to put an animal to sleep painlessly than to have it go crazy from being penned without human love or left to die an agonizing, slow death in the «wild» from hunger, disease, injury or abuse.

These dogs are raised without proper veterinary care and are more likely to have diseases that are transferrable to humans and other animals such as the parvovirus.

Since these cats have no homes, they sometimes live difficult lives exposed to extreme weather, disease, injury and sometimes human abuse, all without medical care or compassion.

In fact, designing veterinary websites without understanding human behavior is like treating disease without understanding germ theory.

Just like with human influenza, most who contract the disease will make a full recovery without intervention.

Tree diseases, and human diseases like West Nile virus and Lyme disease, are becoming much more prevalent — moving up from the south and without good, hard freezes to kill them off.

When natural disaster strikes, one of the first and most significant casualties is clean water: Humans can only go so long without liquids; as days pass without functioning infrastructure, bacteria spread and multiply, as does the threat of disease.

Current models of climate change include sea level rise, land degradation, regional changes in temperature and precipitation patterns, and some consequences for agriculture, but without modeling the feedbacks that these significant impacts would have on the Human System, such as geographic and economic displacement, forced migration, destruction of infrastructure, increased economic inequality, nutritional sustenance, fertility, mortality, conflicts, and spread of diseases or other human health consequences [135,Human System, such as geographic and economic displacement, forced migration, destruction of infrastructure, increased economic inequality, nutritional sustenance, fertility, mortality, conflicts, and spread of diseases or other human health consequences [135,human health consequences [135,136].