Sentences with phrase «human embryogenesis»
Such cells provide a better model of early human embryogenesis than conventional ESCs in later stages of development.
http://wi.mit.edu/
Here we use CRISPR - Cas9 - mediated genome editing to investigate the function of the pluripotency transcription factor OCT4 during human embryogenesis.
First, animal models may not always reflect the nature of human embryogenesis, although the use of an animal model to investigate CIN was unavoidable in our study.
We estimate that approximately three base substitution mutations occur per cell per cell - doubling event in early human embryogenesis and these are mainly attributable to two known mutational signatures.
Genome editing reveals a role for OCT4 in human embryogenesis.
Not exact matches
Having looked at the Reiner and Meyer studies, we in the Johns Hopkins Psychiatry Department eventually concluded that human sexual identity is mostly built into our constitution by the genes we inherit and the embryogenesis we undergo.
In contrast, Neandertals and modern humans share derived wrist morphology that forms during embryogenesis, which diminishes the probability that pathology could result in the normal primitive state.
«Our focus here has been on early heart development, but the basic principles of patterning of human pluripotent stem cells, and subsequently differentiating them, can be readily expanded into a broad range of tissues for understanding embryogenesis and tissue morphogenesis,» said Healy.
«Organ development, especially the liver, is highly conserved among vertebrates — including zebrafish — and the mutations we create in zebrafish alter embryogenesis in a manner consistent with humans, making it an ideal model system to study diseases such as Alagille syndrome.»
«Our focus here has been on early heart development, but the basic principles of patterning of human pluripotent stem cells, and subsequently differentiating them, can be readily expanded into a broad range of tissues for understanding embryogenesis and tissue morphogenesis,» said Dr. Healy.
A mammary stem cell population identified and characterized in late embryogenesis reveals similarities to human breast cancer
Something as radical as making inanimate objects move isn't easy, but many researchers believe that commanding shape change will be invaluable as technology aids and replaces human functions: «Maybe every essential process of life is based on shape transformation: cellular division, the beating of a heart, embryogenesis,» says Nathalie Katsonis, a materials scientist at the University of Twente.