By analysing
human endometrial cells implanted in mice, Jan Brosens at the University of Warwick, UK, and his colleagues discovered that the four - day window is regulated by a molecule called interleukin - 33.
Dienogest, a synthetic progestin, inhibits prostaglandin E (2) production and aromatase expression by
human endometrial epithelial
cells in a spheroid culture system..