Sentences with phrase «human gene responsible»

Liu's experiments began by breeding finches with a singular genetic mutation — the introduction of mHTT, the mutant human gene responsible for Huntington's disease.

The team identified multiple germline mutations in the human genes responsible for SNRK production that were directly associated with higher body mass index, higher waist circumference and risk of obesity in a cohort of 12,000 women who participated in the Women's Health Initiative.

Not exact matches

Furthermore, despite the claim that evolution has no application, phylogenetic comparisons of humans and other organisms allows us to identify the precise location and putative function of genes responsible for developmental disorders.

Actually, science is continually showing us that while no one gene is defined as being responsible for a man or woman being attracted to their own gender, the complex reasoning behind it, much like many other parts of being a human being, is in fact based in genetics, in the physical.

The genes responsible for these proteins undergo frequent point mutations, resulting in genetic «drift»; moreover, the genes from different animal and human strains may also interchange, resulting in genetic «shift.»

Korenberg was convinced that with Mills» approach of directly measuring the brain's electrical firing they could solve the puzzle of precisely which genes were responsible for building the brain wiring underlying the different reaction to human faces in Williams syndrome.

The article also points out that the epitranscriptome could be altered in some human diseases, while alterations in genes responsible for cancer are also being discovered.

Given that in humans HTR7 is also expressed in the neurons that innervate the skin, this new gene may well be responsible for itch in human patients taking antidepressants.

Now researchers have identified a mutation in the human ATP4a gene that is involved in the gastric acid secretion regulation and has been identified as responsible of an aggressive form of inherited, early - onset gastric NET.

The findings hint that the protozoa responsible for toxoplasmosis, amoebic dysentery, malaria, and other diseases may also insinuate themselves into human genes.

Since the successful sequencing of the human genome, interest in the group of genes encoding proteins responsible for DNA remodeling has grown exponentially.

To identify genetic changes likely to be responsible for the giraffe's unique characteristics, including sprints that can reach 37 miles per hour (60 km / h), Cavener and Agaba compared the gene - coding sequences of the giraffe and the okapi to more than forty other mammals including the cow, sheep, goat, camel, and human.

«And the bax gene has a precise counterpart in humans that appears to be responsible for the decimation of eggs during menopause.»

Kapahi said this research could help explain why scientists are having a difficult time identifying single genes responsible for the long lives experienced by human centenarians.

In the study, the working group led by Leopold Eckhart investigated the genes responsible for the skin layers of the shell of the European terrapin and a North American species of turtle, in order to compare them with the genes of human skin.

The HLA (human leukocyte antigen) is a system of genes responsible for regulating immune responses, and peptides are short chains of amino acids that play key roles in regulating the activities of other molecules.

Because many rabbit genes are similar to their human counterparts, manipulating disease genes in rabbits, like the one responsible for cystic fibrosis, may permit researchers to track the disease's onset and better understand what goes awry.

And researchers at Stanford University School of Medicine report in Genome Research that they linked the evolution of a gene in the old platypus to a mutated version in humans responsible for moving the testes outside of the body and into an external pouch, or scrotum.

Just like humans, monkeys are occasionally born with a defective gene that is responsible for some of the color receptors in their retinas, leaving them red — green color - blind.

Now, researchers have found that a gene responsible for clear pronunciation in humans is also critical for proper song development in zebra finches.

Further testing confirmed this in human cells, even those carrying the mutated gene responsible for MPNs in patients.

Research has shown that Drosophila (the genus to which fruit flies belong) can effectively model the genes responsible for genetic kidney disease in humans

Sadly only a few of these are associated with an sufficiently extensive set of evidence such that responsible human trials are an immediate possibility: myostatin knockout for muscle growth and telomerase gene therapies to offset some of the declines of aging.

Furthermore, they identified one gene (DYRK1A) on human chromosome 21, whose overdose in trisomy (DS) is responsible for the observed effects.

The current SNP map now makes it possible for genome - wide association studies to identify genes responsible for diseases and traits, with important consequences for human and companion animal health.

When Parker and colleagues at the National Human Genome Research Institute in Bethesda, MD, went looking for gene responsible for little legs across all these breeds, they expected to find a «point mutation,» a small change in the DNA sequence.

Oxford University researchers have discovered, for the first time, a single gene responsible for increasing insulin sensitivity in humans.

«Williams syndrome presents a unique lens for discovering the how genes form the brain circuitry responsible for human behavior,» explains Korenberg.

Determining the genes responsible may help solve mysteries surrounding human sleep, and help people suffering from sleep disorders.

«We have found that the same genes responsible for tamoxifen resistance in our animals are also turned off in human breast cancer cells that do not respond to the drug,» she says «Because these genes were epigenetically silenced — meaning they were not irreversibly altered, just switched off — it was possible to turn them back on.

Approximately half of gene lesions responsible for human inherited diseases are due to an amino acid substitution.

Dr. Loftus came to the NIH as a postdoctoral fellow in 1996, to the National Center for Human Genome Research (NCHGR) to work as part of a collaborative team with laboratories in both NCHGR and NINDS that was focused on cloning the gene responsible for the neurodegenerative disorder Niemann - Pick disease, type C (NPC).

The human epidermal growth factor receptor - 2 (HER2) gene makes proteins responsible for maintaining healthy cell growth, division and repair of breast tissue.

Loss of function mutations in human Oligophrenin1 (OPHN1) gene are responsible for syndromic intellectual disability (ID) associated with cerebellar hypoplasia and cerebral ventricles enlargement.

The injection helps block pain receptors responsible for migraines — calcitonin gene - related peptides (CGRPs)-- using antibodies cloned from humans.

It is responsible for activating more than 1,000 genes which is approximately 5 % of the human genome (1).

Yellow pea protein has been shown in animal and human studies to have a positive impact on total and LDL cholesterol by downregulating genes involved in fatty acid synthesis and upregulating genes responsible for uptake of cholesterol in the liver.

This gene encodes for ABCA12, a metal binding protein bearing a close functional relationship to ATP7B responsible for Wilsons disease in humans.

The recent identification of the responsible gene mutation in dogs will help scientists better understand the related problem in humans.

This same gene may be responsible for a similar rare, fatal disease in humans.

Samples from canine patients will not only allow the researchers to identify genes responsible for breed - specific susceptibilities (such as hemangiosarcoma in Clumber spaniels and osteosarcoma in Greyhounds), but also to translate these discoveries into new and more precise diagnostics and therapeutics for both canine and human cancer patients.

That raises the possibility of a genetic test for eczema, especially if, as senior author Kerstin Lindblad - Toh suggested in the news release, similar gene mutations are responsible for atopic dermatitis in both dogs and humans.

Pollinger et al., [44] identified a 40 Mb selective sweep on CFA11 associated with black coat color in Large Munsterlander and a 10 MB region on CFA3 in Dachshund containing FGFR3, which is responsible for achondroplasia in humans and presumably linked with related genes responsible for canine chondrodysplasia.

Examining E. coli bacteria, which are responsible for about 80 % of urinary tract infections, the researchers found an identical gene for antibiotic resistance in both humans and animals.