Sentences with phrase «human genetic diversity in»

Not exact matches

For example, in addition to having higher levels of genetic diversity, populations in Africa tend to have lower amounts of linkage disequilibrium than do populations outside Africa, partly because of the larger size of human populations in Africa over the course of human history and partly because the number of modern humans who left Africa to colonize the rest of the world appears to have been relatively low (Gabriel et al. 2002).

How did a 600 year old man, his three sons and their respective mates re-populate the entire human race in all its genetic diversity a mere 4000 years ago?

«It's quite amazing that 50 thousand year - old migrations still leave a mark on current human genetic diversity, but to be able to see this you need a huge amount of data in many populations from different continents.

«We found that interbreeding with archaic humans — the Neanderthals and Denisovans — has influenced the genetic diversity in present - day genomes at three innate immunity genes belonging to the human Toll - like - receptor family,» says Janet Kelso of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany.

We find that mtDNA genetic diversity in Neandertals that lived 38,000 to 70,000 years ago was approximately one - third of that in contemporary modern humans.

Because of the long history of human evolution on the continent, the African genome is rich in genetic diversity.

His message is that the genetic diversity in the oceans is far greater than expected, dwarfing the diversity within human DNA.

He suggests that a database of human values could clarify the diversity of behavior in different cultures and help show how genetic and social factors influence ideas.

Although studying genetic diversity in African populations tells us a great deal about human history, there is even more to learn by juxtaposing the genetic diversity with the diversity of heritable traits (phenotypes).

The technique, similar to DNA profiling in humans, enables scientists to study genetic diversity and connectivity among the Acropora coral populations, thus finding clues to help with the conservation of coral reef ecosystems in waters around Okinawa and the world.

The microbial mass in and on a person may amount to just a few pounds, but in terms of genetic diversity these fellow travelers overwhelm their hosts, with 400 genes for every human one.

This makes him able to explain and to mount a critique of what science today is saying about the biological basis of «race» — in other words, about human genetic diversity.

In addition to offering a view of the origins of humans and their disorders, the new resource of ape genetic diversity will help address the challenging plight of great ape species on the brink extinction.

Except for a dip in the 1940s, genetic diversity in the United States has been increasing every decade since 1920, Amir Kermany, a computational biologist at AncestryDNA, reported October 9 at the annual meeting of the American Society of Human Genetics.

Reported in the journal Nature, the data help to establish a baseline understanding of the diversity of genetic roles in maintaining human tissues.

Anthropologists and geneticists know that populations throughout the world migrated from Africa more than 60,000 years ago (see diagram), and that the human genome is at its most diverse in our continent of origin, but previous studies have only scratched the surface of African genetic diversity.

And human genetic diversity is particularly high in sub-Saharan Africa, so genomes with rare genetic changes can be easily missed.

«Comparing human, chimpanzee and bonobo cells can give us clues to understand biological processes, such as infection, diseases, brain evolution, adaptation or genetic diversity,» says senior research associate Iñigo Narvaiza, who led the study with senior staff scientist Carol Marchetto at the Salk Institute in La Jolla.

Now, evolutionary geneticists have shown that our ancestors lost much of their genetic diversity in two dramatic bottlenecks that sharply squeezed down the population of modern humans as they moved out of Africa between 60,000 and 50,000 years ago.

In addition to the inherited breast and ovarian cancer, her research interests include genetics of hearing loss, the genetic bases of schizophrenia, genetics of systemic lupus erythematosus, and human genetic diversity and evolution.

The limited genetic diversity of dog breeds facilitates identification of genes, functional variants and regulatory pathways underlying complex psychiatric disorders that are mechanistically similar in dogs and humans.

Understanding the genetic diversity in the human host, the parasite and the mosquito vector requires the coordinated effort of researchers around the world, and has a fundamental role to play in malaria control and elimination.

We observed that East African populations exhibit a much larger degree of genetic diversity than other global groups, which further supports the Out - of - Africa theory (that postulates that modern humans originated in East Africa and migrated out of the continent to populate the world)» says Dr. Koehler.

Even though data regarding trends in forest genetic diversity are scarce, a general consensus exists that natural genetic diversity may be at risk globally as a result of human activities (Schueler et al. 2012; Alfaro et al. 2014; FAO 2014).

«This greater genetic diversity in Africa has long been considered part of the justification to consider Africa as having a longer history for modern humans than Asia,» Bae said.

«In addition to our gene - mapping efforts, we try to provide diagnostic expertise for doctors and patients, since the surprising diversity of genetic disorders of human cortical development is only beginning to be appreciated.»

Diversity in Genomics Research Cohorts The lack of diversity within participant cohorts in genetics and genomics research limits our ability to study variation across the human genome and the genetic factors that influence health and disease, as well as our ability to ensure that every segment of the population is able to benefit from advances stemming from the Diversity in Genomics Research Cohorts The lack of diversity within participant cohorts in genetics and genomics research limits our ability to study variation across the human genome and the genetic factors that influence health and disease, as well as our ability to ensure that every segment of the population is able to benefit from advances stemming from the diversity within participant cohorts in genetics and genomics research limits our ability to study variation across the human genome and the genetic factors that influence health and disease, as well as our ability to ensure that every segment of the population is able to benefit from advances stemming from the research.

Currently, I study the prevalence, genetic diversity and evolutionary history of Demodex lineages, in relation to both human populations, as well as other mammalian hosts.

«In the area of oncology, but even more generally, embracing the genetic diversity of disease is really important,» says Golub, who is also director of the Broad's Cancer Program, the Charles A. Dana Investigator in Human Cancer Genetics at Dana - Farber, professor of pediatrics at Harvard Medical School, and a Howard Hughes Medical Institute investigatoIn the area of oncology, but even more generally, embracing the genetic diversity of disease is really important,» says Golub, who is also director of the Broad's Cancer Program, the Charles A. Dana Investigator in Human Cancer Genetics at Dana - Farber, professor of pediatrics at Harvard Medical School, and a Howard Hughes Medical Institute investigatoin Human Cancer Genetics at Dana - Farber, professor of pediatrics at Harvard Medical School, and a Howard Hughes Medical Institute investigator.

South Asian genetic landscape, bearing in mind its geographic, linguistic, socio - cultural and skin color diversity, offers an excellent model system to decipher the genetic underpinnings of human skin color variation and for a better understanding of it's evolutionary history.

A group of scientists at Stanford University have collaborated on a large study to understand genetic diversity in human populations.

The antiviral restriction factor IFN - induced transmembrane protein 3 (IFITM3) inhibits cell entry of a number of viruses, and genetic diversity within IFITM3 determines susceptibility to viral disease in humans.

«The high - resolution portrait of human genetic diversity afforded by these studies allows new inferences to be made about our migration out of Africa,» write Serena Tucci and Joshua Akey in an accompanying News & Views article.

The notion of family is seminal in human genetics for many reasons: the inheritance and genetic basis of traits is discerned from family patterns; arguments about heritability and nature versus nurture are derived from studies of family relationships; population genetic structure and social diversity are determined by patterns of mate choice; genetic information is typically delivered in the context of families.

However, genetic differentiation between groups in Papua New Guinea is much stronger than in comparable regions in Eurasia, demonstrating that such a transition does not necessarily limit the genetic and linguistic diversity of human societies.

In doing so, it shall take account of the dignity of living beings as well as the safety of human beings, animals and the environment, and shall protect the genetic diversity of animal and plant species.

At the present time, an insufficient number of the countries from this correlation are represented in the genetic databases [e.g. HapMap (International HapMap Consortium, 2005) and Human Genome Diversity Panel (Li et al., 2008)-RSB- to determine if the present results are significantly different from the frequency distribution of randomly selected alleles from representatives of each of these countries.

A report entitled «Bioethics and human population genetic research» submitted to the third session of the UNESCO International Bioethics Committee in November 1996 pointed out that there is greater diversity within populations than between them and that population geneticists note that population genetics offers no scientific basis for the belief that certain races (however defined) are superior to other races.

Likely, this desire for intensity is left over from another time in human history, when it was needed to encourage genetic diversity and survival of the species.