Sentences with phrase «human genome sequence for»

In the postgenomic era, the availability of human genome sequence for genome - wide analysis has revealed higher - order architectural features (i.e., beyond primary sequence information) that may cause genomic instability and susceptibility to genomic rearrangements.

The Archon Genomics X PRIZE presented by MEDCO was established in 2006 by the X PRIZE Foundation in Playa Vista, California, to encourage the rapid development of cheap, accurate human genome sequencing for medical purposes.

Complete Genomics, a Mountain View, California - based biotechnology company last year claimed it would soon be able to sell full human genome sequences for as little as $ 5000 apiece.

Not exact matches

Venter, who is one of the first people to sequence the human genome, co-founded the company in effort to discover early genetic markers for a variety of disorders.

Just last month, the genomic sequencing company Illumina announced it had developed a genome sequencer that can map the human genome for just $ 1,000.

By increasing the speed and accuracy for NGS data analysis like whole genome sequencing (WGS), our computing platform makes it easier to discover links between DNA sequence variations and human disease.»

Venter explained that when he first sequenced the human genome 15 years ago, there was nothing for him to compare it to.

The, members of the workshop believe that knowledge gained from mapping and sequencing the human genome can have great benefit for human health and well being.

The first human genome sequence was published the year that Wood began graduate school, providing strong evidence for evolution.

All the technologies for sequencing the human genome have been developed in this country.

An international team led by researchers with the Lawrence Berkeley National Laboratory (Berkeley Lab) has developed a new technique for identifying gene enhancers — sequences of DNA that act to amplify the expression of a specific gene — in the genomes of humans and other mammals.

BOSTON — For bee researchers like May Berenbaum, 2006 was the year an international consortium of researchers published the first full sequence of the honeybee genome, offering a unique and long - sought glimpse at the biological quirks of an insect that shares a productive history with humans.

The man responsible for one of the original sequences of the human genome as well as the team that brought you the first living cell running on human - made DNA now hopes to harness algae to make everything humanity needs.

Their work has made it increasingly clear that for all the popular attention devoted to genome - sequencing projects, the epigenome is just as critical as DNA to the healthy development of organisms, humans included.

Now Pääbo and his colleagues have devised a new method of genetic analysis that allowed them to reconstruct the entire Denisovan genome with nearly all of the genome sequenced approximately 30 times over akin to what we can do for modern humans.

New methods for the removal of contaminating DNA from microbes and present - day humans that were developed by the Leipzig group have now enabled the researchers to sequence the genomes of five Neandertals from Belgium, France, Croatia, and Russia that are between 39,000 and 47,000 years old.

The luck continued when Viola's colleagues found that the bone contained well - preserved DNA, and they sequenced its genome to the same accuracy as that achieved for contemporary human genomes (Q. Fu et al.Nature 514, 445 — 449; 2014).

«We explored the opportunity of using sperm RNA elements as a predictor of human health, with applications at the fertility clinic that would go hand - in - hand with the new neonatal intensive care unit genome sequencing to better health outcomes,» said Dr. Krawetz, associate director of the C.S. Mott Center for Human Growth and Develophuman health, with applications at the fertility clinic that would go hand - in - hand with the new neonatal intensive care unit genome sequencing to better health outcomes,» said Dr. Krawetz, associate director of the C.S. Mott Center for Human Growth and DevelopHuman Growth and Development.

Using advanced sequencing technologies, University of Oklahoma anthropologists demonstrate that human DNA can be significantly enriched from dental calculus (calcified dental plaque) enabling the reconstruction of whole mitochondrial genomes for maternal ancestry analysis — an alternative to skeletal remains in ancient DNA investigations of human ancestry.

Encased in ice for 4,000 years, a clump of prehistoric human hair gave up its secrets to the University of Copenhagen's Eske Willerslev, the first researcher to sequence an ancient human genome.

«Once we can build that sort of database for the human organism, it helps us much better understand disease, how to diagnose disease, how better to treat disease,» says Richard Wilson, the director of the Genome Sequencing Center at Washington University in St. Louis.

The sequencing of the human genome has made it possible: nowadays scientists can discover potential disorders for which there are no known patients.

Over the course of a year, a committee led by Green and Leslie Biesecker, chief of the Genetic Disease Research Branch at the National Human Genome Research Institute in Bethesda, Maryland, has been weighing how to handle «incidental findings» that turn up when a genome or exome is sequenced for some other medical rGenome Research Institute in Bethesda, Maryland, has been weighing how to handle «incidental findings» that turn up when a genome or exome is sequenced for some other medical rgenome or exome is sequenced for some other medical reason.

The trust now plans to increase its spending from $ 160 million to $ 325 million over 7 years at the Sanger Centre near Cambridge — Britain's main gene sequencing laboratory — for more painstaking efforts to sequence a third of the human genome by 2005.

The move comes in response to the announcement earlier this week of a new U.S. company, launched by sequencing - machine manufacturer Perkin - Elmer and J. Craig Venter of The Institute for Genomic Research, that plans a brute - force approach to sequencing the human genome within 3 years (ScienceNOW, 12 May).

«Sequencing the human genome, device miniaturization, and the advent of combination devices have shifted the focus from engineering to the life sciences in the device industry,» adds Jules Mitchel, president of Target Health Inc. in New York City, a company that conducts clinical trials for MD&D companies.

The rationale for sequencing and exploring the human genome — to revolutionize the finding of new drugs, diagnostics and vaccines, and to tailor treatments to the genetic make - up of individuals — is the same today.

«This was the ultimate in identity theft,» says Venter, a biologist well known for his private - sector contribution to the sequencing of the human genome.

In the last decade, however, complete genome - sequence information and increasingly powerful bioinformatic tools have allowed us to generate and analyse draft interactome maps both for humans and for other model organisms.

The sequencing of the human genome is gearing up all those efforts, and with each novel model organism for which the sequence has been determined, the power of comparative analysis increases.

Work is expected to begin as soon as participants at genome centers in the United States and abroad agree on some ground rules for the project, perhaps the most unwieldy collaboration since the sequencing of the human genome.

His laboratory develops and deploys new biochemical and computational methods in functional genomics, to elucidate the genetic basis of human disease and human physiology, and to create and deploy novel techniques in next - generation sequencing and algorithms for tumor evolution, genome evolution, DNA and RNA modifications, and genome / epigenome engineering.

«St. Laurent Institute has adapted true single - molecule sequencing technology to global transcriptome analysis, providing state - of - the - art technology for the measurement of the output of the human genome,» said Georges St. Laurent III, Scientific Director of the St. Laurent Institute.

Sequencing the human genome cost roughly $ 500 million, and essentially all that scientists had to show for the money was a long string of letters that make up human DNA.

Hidden in the tangled, repetitious folds of DNA structures called centromeres, researchers from Harvard Medical School and the Broad Institute have discovered the hiding place of 20 million base pairs of genetic sequence, finding a home for 10 percent of the DNA that is thought to be missing from the standard reference map of the human genome.

Just as the Human Genome Initiative in the 1990s sequenced human DNA for the subsequent identification and analysis of genes, so too will the Materials Genome Initiative sequence materials for identifying new properties for a variety of applicatHuman Genome Initiative in the 1990s sequenced human DNA for the subsequent identification and analysis of genes, so too will the Materials Genome Initiative sequence materials for identifying new properties for a variety of applicathuman DNA for the subsequent identification and analysis of genes, so too will the Materials Genome Initiative sequence materials for identifying new properties for a variety of applications.

As scientists race to decode genomes — not just of humans but of bacteria, yeast, chimps, dogs, whales and plants — the number of DNA sequences available for analysis has grown 40,000-fold in the past 20 years, providing unprecedented insight into billions of years of species evolution.

The sequencing of the N. furzeri genome represents a milestone for human aging research - since almost all genes of the little fish are also present in humans.

It may do for geoscience what human genome sequencing did for biology

The research team from the National Human Genome Research Institute (NHGRI) and the National Cancer Institute (NCI), both parts of NIH, extended their recent genome sequencing study of skin bacteria, using DNA sequencing techniques optimized for identifying Genome Research Institute (NHGRI) and the National Cancer Institute (NCI), both parts of NIH, extended their recent genome sequencing study of skin bacteria, using DNA sequencing techniques optimized for identifying genome sequencing study of skin bacteria, using DNA sequencing techniques optimized for identifying fungi.

With the completion of the first phase of the Human Genome Project in 2000, and the advent of sequencing technologies that can detect gene variations such as single nucleotide polymorphisms (SNPs), for the first time scientists have the tools in hand to find the key immune genes and genetic networks that play roles in vaccine response.

The advent of large - scale genome sequencing has helped scientists identify DNA bacteriophages in the human gut, skin and blood as well as in the environment, but few researchers have looked for RNA bacteriophages in those samples.

But the primary sequences of the human, mouse, and rat genomes are also tools from which we can derive the protein sequence for each gene.

Since the successful sequencing of the human genome, interest in the group of genes encoding proteins responsible for DNA remodeling has grown exponentially.

Evolutionary geneticists Svante Pääbo, Johannes Krause, and colleagues at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, ground up a 30 - milligram sample and extracted and sequenced all of the 16,569 base pairs of its mtDNA genome, using new techniques Pääbo's group has successfully employed to sequence both Neandertal and prehistoric modern human DNA.

The researchers were searching for archaic DNA sequences in those human genomes at frequencies much higher than would be expected if those genes weren't doing people any good.

The three centers that pulled down the biggest grants are those with the lion's share of the U.S. contribution to human genome sequence: Baylor College of Medicine in Houston, the Whitehead Institute for Biomedical Research in Cambridge, Massachusetts, and Washington University School of Medicine in St. Louis.

The nematode project is also seen as an ideal way of perfecting the mapping and sequencing strategies researchers will need for their final assault on the human genome, which is some 30 times bigger.

When researchers decided to sequence the human genome in the late 1990s, they were focused on finding those traditional genes so as to identify all the proteins necessary for life.

Meanwhile, Illumina, by far the biggest maker of sequencing machines, is about to introduce a 10 - machine system that can produce 18,000 human genomes per year for less than $ 1000 a piece.