Sentences with phrase «human genomic cancer»

May 15, 2013 University of Chicago launches cloud to analyze cancer data The University of Chicago is launching the first secure cloud - based computing system that will enable researchers to access and analyze human genomic cancer information without the costly and cumbersome infrastructure normally needed to download and store massive amounts of data.

Not exact matches

Sir John Bell, professor of medical sciences at Oxford University and government advisor on human genomics believes this will transform cancer treatment in the UK.

The U.S. National Institutes of Health (NIH) has made major investments in network approaches in many areas, including cancer biology, cardiovascular and metabolic diseases, neurophysiology, and human genetics and genomics.

Using genomic analysis to study cancer in dogs can help develop new therapies for humans with cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (cancer in dogs can help develop new therapies for humans with cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (cancer, according to a proof - of - concept study led by the National Cancer Institute (NCI) and the Translational Genomics Research Institute (Cancer Institute (NCI) and the Translational Genomics Research Institute (TGen).

Lead author Moustafa Abdalla writes: «Almost all genomic studies of breast cancer have focused on well - established tumours because it is technically challenging to study the earliest mutational events occurring in human breast epithelial cells.»

Tamayo and team tested REVEALER using The Cancer Genome Atlas (TCGA), the National Institutes of Health's database of genomic information from more than 500 human tumors representing many cancer Cancer Genome Atlas (TCGA), the National Institutes of Health's database of genomic information from more than 500 human tumors representing many cancer cancer types.

«So perhaps in this age of cancer genomics showing how diverse and heterogenous human cancer is, we should be focusing on the common effects that different mutations lead to,» he says.

The study analyzed data from The Cancer Genome Atlas (TCGA), a research program supported by the National Cancer Institute and National Human Genome Research Institute within the National Institutes of Health that is looking at genomic changes in more than 20 different types of cCancer Genome Atlas (TCGA), a research program supported by the National Cancer Institute and National Human Genome Research Institute within the National Institutes of Health that is looking at genomic changes in more than 20 different types of cCancer Institute and National Human Genome Research Institute within the National Institutes of Health that is looking at genomic changes in more than 20 different types of cancercancer.

The Cancer, Ageing and Somatic Mutation Programme encompasses three Projects that respectively cover the genomics of human cancers; functional analysis of the cancer genome using a range of in vitro and in vivo model systems; and the characterisation of somatic mutations in development and adult homeostasis in health and diCancer, Ageing and Somatic Mutation Programme encompasses three Projects that respectively cover the genomics of human cancers; functional analysis of the cancer genome using a range of in vitro and in vivo model systems; and the characterisation of somatic mutations in development and adult homeostasis in health and dicancer genome using a range of in vitro and in vivo model systems; and the characterisation of somatic mutations in development and adult homeostasis in health and disease.

Participating institutions: Helmholtz Association • CNRS • Institute of Molecular Biotechnology • Research Center for Molecular Medicine of the Austrian Academy of Sciences • VIB - KU Leuven • Friedrich Miescher Institute for Biomedical Research • University of Basel • University of Zurich • Central European Institute of Technology • Max Planck Institute of Immunobiology and Epigenetics • Max Planck Institute for Molecular Genetics • German Cancer Research Center • Max Delbrück Center for Molecular Medicine • German Center for Neurodegenerative Diseases • Helmholtz Zentrum München • Max Planck Institute for Evolutionary Anthropology • Helmholtz Institute of RNA - based Infection Research • Saarland University • Technical University Munich • University of Würzburg • Biotech Research & Innovation Centre • Interdisciplinary Nanoscience Center • University of Copenhagen • Centre for Genomic Regulation • Institut Curie • Université de Montpellier • Inserm • Université Toulouse III — Paul Sabatier • École nationale supérieure des mines de Paris • Institute for Molecular Medicine Finland • The Biomedical Research Foundation, Academy of Athens • Weizmann Institute of Science • Hebrew University • Sapienza — University of Rome • Instituto Nazionale Genetica Molecolare • University of Napoli • University of Padua • University of Milan • European Institute of Oncology • Netherlands Cancer Institute • Radboud University • University Medical Center Utrecht • Hubrecht Institute • Instituto Gulbenkian de Ciência • Institute of Bioorganic Chemistry of the Polish Academy of Sciences • Romanian Center for Systems Immunology • Karolinska Institute • MRC Human Genetics Unit • University of Edinburgh • Wellcome Sanger Institute • The Babraham Institute • European Molecular Biology Laboratory — European Bioinformatics Institute

Major focus areas include human genome interpretation and genetic dissection of novel rare diseases, predictive genomic signatures of response to therapy — especially cancer therapy, and novel sequencing - based assays as biomarkers of disease.

Elected by his peers, Liu was recognized for his distinguished contributions to cancer biology, particularly the molecular analysis of breast cancer, and to the global advancement of human genomics.

Aug 8, 2008 Two New Predisposition Genes For Breast, Thyroid And Kidney Cancers Could Lead to More Accurate Diagnosis and Earlier Detection of These Cancers Charis Eng, MD, PhD, Sondra J and Stephen R Hardis Endowed Chair of Cancer Genomic Medicine and Chair, GMI, and her team published in the Aug 8, 2008 issue of the American Journal of Human Genetics that germline mutations in SDHB and SDHD, which play key roles in the mitochondria (the cell's power houses), predispose to Cowden and Cowden - like syndromes.

Liu's scientific research focuses on the functional genomics of human cancers, particularly breast cancer, uncovering new oncogenes, and deciphering on a genomic scale the dynamics of gene regulation that modulate cancer biology.

The HDCA programme will create genomic reference maps of all the cells that are important for human development, which will revolutionise our understanding of health and disease, from miscarriages and children's developmental disorders, through to cancer and ageing.

His honours and awards include the inaugural Gutenberg Professorship of the University of Strasbourg, the Order of Australia and Australian Government Centenary Medal, Fellowship of the Australian Academy of Science, Associate Membership of the European Molecular Biology Organization, Honorary Fellowship of the Royal College of Pathologists of Australasia, the International Union of Biochemistry & Molecular Biology Medal, the Human Genome Organisation Chen Award for Distinguished Achievement in Human Genetic & Genomic Research, and the University of Texas MD Anderson Cancer Center Bertner Memorial Award for Distinguished Contributions to Cancer Research.

Human cancers exhibit a diverse array of genomic gains and losses that alter the dosage of hundreds of genes at once.

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Investigations of this phenomenon may provide unique access to understanding genomic disorders, structural variant mutagenesis, human evolution, and cancer biology.

Laboratory activities minimally include performing a lab - based patient - oriented research project applicable to cancer genomics, with an emphasis on mastering techniques commonly used within a human genetics laboratory, such as PCR, gene sequencing, mutation analysis, western blots, and functional protein studies.

Integrative annotation of variants from 1092 humans: application to cancer genomics.

Massively parallel sequencing (next - generation sequencing) has revolutionized research in cancer genetics and genomics [1] and enhanced our understanding of natural human genetic variation [2], [3].

Examples include the study of allelic variation in the human genome and the development of computational methods for the discovery of cancer - associated genes and diagnostic cancer markers using genomic profiles derived from different tumor types.

In this session, we will discuss methods for integrated analysis of DNA and RNA and their application in human genomic research in the areas of cancer genomics, human disease research, and regulation of gene expression.

This centre has been devised as a space for excellence research in genomic medicine, focussing on the comprehensive study and understanding of the genetic basis of human diseases in general, placing special emphasis on cancer and its genetic disorders related to inheritance.

Tags: cancer genomics, Carla Grandori, Christopher J Kemp, Clinical Research, Eddie Mendez, Good News, head neck cancers, Human Biology, Jerald P Radich, personalized treatment, precision medicine, Tumor specific translational research, Vijayakrishna Gadi

From our earliest research that established cancer as a genetic disease to today's work in precision medicine, our unswerving focus on genetics and genomics continues to generate advances that improve human health.

Genomic rearrangements are a hallmark of human cancers.

GENYO is the first national centre devoted to genomics that integrates the Public Administration, the University and the biotechnology and pharmaceutical business sector, which would allow the integration of research in all its phases, from the generation of knowledge to its development in clinical and pharmaceutical applications, the development of new projects and services for the prevention, diagnosis and treatment of diseases associated to human genetic variability, such a cancer and rare diseases, diabetes, hypertension or degenerative diseases, among others.

These molecular subtypes have recently been confirmed in a comprehensive characterization of human breast tumors at the genomic, epigenetic, transcriptomic, and proteomic levels (Cancer Genome Atlas Network, 2012).

Innovative research using comparative genomics has helped us identify unique molecular signatures that are associated with disease progression and can thus be used to prognosticate and personalize therapies for dogs and humans with cancer.

My primary research interests are human genetics and cancer genomics, and the content of my blog reflects that.