Sentences with phrase «human glioblastoma with»
Figure 2: Abnormal accumulation of the FGFR - TACC fusion protein (red) in glioblastoma stem cells isolated from a primary human glioblastoma with fused FGFR - TACC genes.
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The investigators report that trapping virus - loaded stem cells in a gel and applying them to tumors significantly improved survival in mice with glioblastoma multiforme, the most common brain tumor in human adults and also the most difficult to treat.
Shah next plans to rationally combine the toxin - secreting stem cells with a number of different therapeutic stem cells developed by his team to further enhance their positive results in mouse models of glioblastoma, the most common brain tumor in human adults.
Into the cerebral cortex of mice with these light - sensitive proteins, the team implanted cancer cells from a human pediatric cortical glioblastoma.
These results could pave the way for the use of progesterone against glioblastoma in a human clinical trial, perhaps in combination with standard - of - care therapeutic agents such as temozolomide.
Calorie restriction has been used effectively to treat malignant glioblastoma multiforme in mice, which shares many characteristics with human glioblastoma multiforme, the most aggressive and invasive primary human brain cancer [3].