Researchers have found
human gut bugs such as Escherichia coli in ape droppings — not surprising, as these bacteria persist in the environment, where eco-tourists with diarrhoea deposit them.
Dennis Kasper at Harvard Medical School and his colleagues found that mice inoculated with Bacteroides fragilis —
a human gut bug that produces a molecule called PSA — were able to fend off colitis provoked by the pathogenic bacterium Helicobacter hepaticus.
Not exact matches
The scientists will have to demonstrate that a vaccine can block UTI - causing E. coli in
humans while sparing another colony of E. coli: the beneficial intestinal flora that prevent disease - producing
bugs from proliferating in the
gut.
Moeller found that two of three major families of
gut bacteria in apes and
humans trace their origins to a common ancestor more than 15 million years ago, not primarily to
bugs picked up from their environment.
A valuable result of this work, they both agree, is that it sets up a way to test the effects of microbial therapies on
human gut bacteria (even though the
bugs are living in a mouse).
The
bugs in
human guts are a hot topic these days.