Sentences with phrase «human heart failure»

Ultimately the goal is to translate this work to gene transfer treatment approaches for canine idiopathic dilated cardiomyopathy and human heart failure.

«We also believe our current work has important near - term translational impact in human heart failure.

The current study found that mice meant to serve as a model of ischemic human heart failure (weaker blood flow after a heart attack) had higher levels of activated, pro-inflammatory macrophages, monocytes, dendritic cells and T cells trafficking between their hearts and spleens than did control mice with healthy hearts.

Because they are interested in human heart failure, Lavine and his colleagues developed a method to progressively damage mouse cardiac tissue in a way that mimicked heart failure.

Not exact matches

Over the course of cultural evolution, due to an impotence at the heart of the will and to recurrent failures in ever - renewed struggles for ascendency, human will to power lost its good cheer and creatively turned against itself.

There are hundreds of thousands of fans who remain sane when the Western New York winter dumps a human's worth of snow on them, only to be driven nuts by the constant failures of the Buffalo Bills, and if you don't feel for these people from the bottom of your heart, then you don't have a human soul.

Human embryonic stem cells are at last being tested in common, potentially fatal diseases such as heart failure and diabetes

Trials of cells made from human embryonic stem cells are also poised to begin in people with type 1 diabetes and heart failure, the first time embryonic stem cells have been used in the treatment of major lethal diseases.

Decades after they were discovered, human embryonic stem cells are being trialled as a treatment for two major diseases: heart failure and type 1 diabetes

We would expect our findings can help in the prediction and prevention of heart failure among African Americans,» said Yu, assistant professor in the Department of Epidemiology, Human Genetics and Environmental Sciences at UTHealth School of Public Health.

«Once we've shown that this can safely be used in human patients with pulmonary hypertension — and we've got a clinical trial in progress right now — we'll be able to conduct studies of inhaled NO delivered in ambulatory settings, including patients» homes, to treat chronic pulmonary hypertension, right - sided heart failure and chronic obstructive pulmonary disease.»

Unlike most other cells in the human body, heart cells do not have the ability to self - repair or regenerate effectively, making heart attack and heart failure severe and debilitating.

And high levels of it have been linked to heart disease, diabetes and liver failure in humans, according to the Journal of the American Medical Association.

But before these drugs can be evaluated in people with heart failure, more work must be done to find out whether the same mechanisms are at work in human hearts, according to the researchers.

«Based on our findings, we are highly motivated to bring a drug - like derivative of JQ1 forward as a new type of heart failure drug for humans,» Haldar says.

Recently, Gladstone Senior Investigator Yadong Huang, MD, PhD, found that a drug used for years to treat heart failure also seems to reverse signs of Alzheimer's disease in both human and mouse brains.

By supporting Directive 2010 / 63 / EU, LERU wishes to call attention to the fundamental importance of the use of animals in research and the vital role it plays in understanding and providing treatment for a range of debilitating and life threatening human diseases such as cancer, primary immunodeficiencies, neuro - degenerative diseases and heart failure.

Dr. Nobrega has modeled the impact of mutations implicated in various human diseases, such as congenital heart defects, heart failure, cancer, type 2 diabetes, obesity, and asthma.

Symposia VI: Cardiovascular Benefits of Exercise: Insights from Human Studies The session will cover improving exercise tolerance in heart failure, reversal of impaired cardiac function in obese adolescents, the effect of exercise on left ventricular compliance and diastolic function in the elderly and attenuating premature cardiovascular aging in Type 2 diabetes through exercise.

Plenary Lecture: Muscle Sympathetic Reflexes in Humans Lawrence I. Sinoway, Director of the Penn State Hershey Heart and Vascular Institute, leads the discussion on the exercise pressor reflex and how it is altered in cardiovascular disease, such as heart failHeart and Vascular Institute, leads the discussion on the exercise pressor reflex and how it is altered in cardiovascular disease, such as heart failheart failure..

«We tested the drug on human cardiomyocytes, as they are cells that not only beat, but can also trigger the processes of inflammation and fibrosis, which in turn make heart failure progressively worse.

With this study, the scientists found that JQ1 can effectively treat severe, pre-established heart failure in both small animal and human cell models by blocking inflammation and fibrosis (scarring of the heart tissue).

Human chronic heart failure patients have also been shown to have reduced gut bacterial diversity and lower abundance of key bacterial genera (20).

This includes cardiovascular disease; hypertension; heart failure and transplant; pulmonary disease; renal disorders; cancer; human immunodeficiency virus (HIV) disease; metabolic stress (sepsis, trauma, burns, and surgery); neurologic disorders; rheumatic disorders; and metabolic disorders.

The first and last lines include the word «heart,» and I think that they have a double meaning: aside from the surface meaning, they also describe our attempt and failure as humans to truly connect with each other.

Mistry evokes laughter and tears as he spins the great wheel of human life and charts the soul's confusion and the body's decline, the endless cycle of repeated mistakes and failures of heart, and, yes, the radiant revelations of love.

A wide variety of medications, developed to treat human heart conditions, are used to successfully delay the progression of heart failure.

NSAIDS like Rimadyl, as well as prednisone, increase blood pressure in humans; if this occurs in dogs as well, we need to know so that we don't unduly stress older dogs or dogs already in heart failure.

For example, congestive heart failure means diet and medication, just as for humans.

Heart diseases in pets include congenital heart diseases (from birth), cardiomyopathy (disease of the heart muscle), valvular heart disease (disease of the heart valves) and, just like in humans, congestive heart faiHeart diseases in pets include congenital heart diseases (from birth), cardiomyopathy (disease of the heart muscle), valvular heart disease (disease of the heart valves) and, just like in humans, congestive heart faiheart diseases (from birth), cardiomyopathy (disease of the heart muscle), valvular heart disease (disease of the heart valves) and, just like in humans, congestive heart faiheart muscle), valvular heart disease (disease of the heart valves) and, just like in humans, congestive heart faiheart disease (disease of the heart valves) and, just like in humans, congestive heart faiheart valves) and, just like in humans, congestive heart faiheart failure.

In humans, this is essentially a surgical disease with surgery being a treatment of choice however due to the limitations in the veterinary field as mentioned above, medical management of congestive heart failure is still the mainstay of treating the condition in dogs.

In human healthcare, preventive medicine is a very important tool for detecting underlying disease such as diabetes, heart failure, and liver dysfunction.

In fact, a large percentage of dogs have been known to develop congestive heart failure a few years post infection, after the human in the relationship has all but forgotten about his mess with parvovirus.

The most fascinating response was that of Philip Guston, who seemed to come out of the other side of abstraction into an alternative world of figuration, ironic, often amusing, but at heart deadly serious about human failure, and how hollow the pose of artistic heroism had become.

Sumi Kang formulates a theory that failure is at the heart of the development of the human worldview and civilization, which connects to the notion of failure as one of the most significant forces in the history of avant - garde art.