Sentences with phrase «human hemophilia»

The parents of any Frenchie should be screened for hip dysplasia (OFA), eye problems (CERF) and von Willebrand's disease (a canine bleeding disease that's similar to human hemophilia).

Concerns about immunological consequences of rAAV - mediated gene transfer were substantiated by the outcome of a clinical trial in which human hemophilia B patients were infused into the liver with rAAV -2-F.

Not exact matches

Scottish researchers took a similar approach to clone sheep that will produce in their milk human factor IX protein, which is used to treat hemophilia.

Imagine if genetic diseases could be removed from the very biological code of our species — a future in which the likes of hemophilia, cystic fibrosis or dozens of other afflictions are simply edited out of human embryos.

The method, reported in the November issue of Nature Biotechnology, could lead to safe and effective human gene therapies for cystic fibrosis, hemophilia, and a variety of other diseases.

Jiang estimates that human clinical trials could begin within a decade: «At first, the cells could be used to treat diseases with single missing or malfunctioning cell types, like hemophilia, diabetes, Parkinson's disease, and muscular dystrophy.

An antibody engineered to prevent excessive bleeding in patients with severe hemophilia A may be safe and effective, and require fewer injections than existing options, according to a first - in - human study of the treatment published online today in Blood, the Journal of the American Society of Hematology (ASH).

«Antibody for severe hemophilia a may reduce injections needed to prevent bleeding: First - in - human study of ACE910 suggests excessive bleeding prevention is possible with a weekly subcutaneous injection compared to standard two or three intravenous injections every week, and should be effective in treating patients with inhibitors.»

To create a longer - lasting preventive therapy for severe hemophilia A-associated bleeding, a group of Japanese researchers launched a first - in - human Phase I trial to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of ACE910, a bispecific antibody that mimics FVIII and works with other clotting factors to make the blood clot properly.

Peppas and Horava's work has been patented and builds upon their published and patented system for the oral delivery of human factor IX (hFIX), a prophylactic treatment for hemophilia B patients.

On Wednesday we were saddened learned that double Nobel laureate Fred Sanger had died, so it was fitting that yesterday also saw the announcement of an important scientific advance that owes everything to the molecular biology revolution he helped to launch — one that may improve the lives of many thousands of people with Hemophilia A.... Continue reading Successful gene therapy for hemophilia A in dogs — humans next!

However, they say the work at least proves the potential for mRNA therapy to successfully treat not only hemophilia B but also other human disorders, such as hemophilia A (caused by faulty clotting factor VIII) or a variety of diseases of the liver, central nervous system, lung and eyes.

Von Willebrand disease, which is similar to hemophilia in humans, is also present in some German Shepherd bloodlines.

Factor VIII deficiency or hemophilia A: the most common severe inherited clotting disorder of humans and nonhuman animals.

She worked with animals with diseases like hemophilia, and during the early 1980s she ran New York's human blood program, which made her realize that veterinary medicine could benefit from something similar.

Frenchies can suffer from Von Willebrand's disease (VWD), a bleeding disorder that is also found in humans and is similar to hemophilia, which can impede their clotting.

That said, here are a few things to watch out for when buying a terrier puppy or caring for your dog... von Willebrand's Disease Also referred to as vWD, von Willebrand's disease is an inherited condition that may lead to excessive bleeding, similar to hemophilia in humans.

Because dogs get about 220 of the same inherited diseases and disorders that humans do — including Alzheimer's, muscular dystrophy, hemophilia and retinal degeneration — medical researchers are able to study the underlying genetic defects and, through dogs, seek cures.

Today academic institutions and teaching hospitals across the country receive federal or private grants to support groundbreaking research using human fetal tissue on a wide range of conditions including diabetes, Parkinson's disease, Alzheimer's disease, spinal cord injuries, hemophilia, leukemia, sickle cell anemia, cortical blindness, fetal aneuploidy, ALS, and others.