Sentences with phrase «human immune receptor»
«The strategy of using peptides that mimic regions of a human immune receptor, to put the brakes on the excessive inflammatory response triggered by superantigen toxins, is a host - oriented strategy that is broadly effective against the diverse family of superantigens,» said Prof. Raymond Kaempfer.
https://www.sciencedaily.com/ Not exact matches
A 2 - year fellowship from the Human Science Frontier Program financed a postdoc at Yale University School of Medicine on the role of so - called «toll - like receptors» in immune responses.
The result, published January 5 in Science Immunology, suggests that the protein, a receptor involved in immune cell signaling, plays a role in spontaneous abortions and other human pregnancy complications.
Δ9 - THC binds to two types of proteins in the human body: the cannabinoid CB1 receptor in the brain and the cannabinoid CB2 receptor in the immune system.
Newly - discovered mechanism of action of the bacterial superantigen toxins: Superantigens bind to both B7 - 2 and CD28, the major costimulatory receptors expressed on human immune cells.
Organ transplantation is a challenge, requiring immunosuppressive drugs and careful matching of donor and recipient for human leukocyte antigen markers, receptors on immune cells that recognize foreign proteins.
Varki studies siglecs, small groups of receptors that thickly stud the immune T cells of monkeys and apes but are few and far between in humans.
TNA3: BPRC will offer access to its library of human cell reporter assays for the identification of innate immune receptor - induced signalling cascades, including human cell lines transfected with PAMPs such as TLR and / or engineered to express luciferase in response to NF - kB or IFRE - mediated signal transduction, and cell lines that provide insight into the intracellular signalling cascades of innate immune receptors.
Called immunodeficient IL2 receptor gamma (IL2rl) null mice, these animals lack the IL2ry receptor that humans also have as part of a functional immune system.
LA JOLLA — When a receptor on the surface of a T cell — a sentry of the human immune system — senses a single particle from a harmful intruder, it immediately kicks the cell into action, launching a larger immune response.
Robert D. Schreiber, Ph.D., an associate director of CRI's Scientific Advisory Council based at Washington University School of Medicine in Saint Louis, Missouri, developed a new model of breast cancer that more closely resembles the progression of hormone receptor - positive disease in humans, overcoming a major obstacle in the study of breast cancer and the development of new immune - based therapies for the disease.
BPRC will offer access to its library of human cell reporter assays for the identification of innate immune receptor - induced signalling cascades, including human cell lines transfected with PAMPs such as TLR and / or engineered to express luciferase in response to NF - kB or IFRE - mediated signal transduction, and cell lines that provide insight into the intracellular signalling cascades of innate immune receptors.
Gram - negative bacteria universally produce endotoxins that have been shown to be powerful immune system modulators through the Toll - like receptor 4 (TLR4) on a variety of human immune cells.