Sentences with phrase «human immune response to infection»

However, the spikes present new binding sites for the human immune response to infection and as such, may present promising new targets for the development of different types of drugs.

Not exact matches

«As you look for methods to discern complex immune responses in human cells, more and more people look at what genes are turned on with infections or vaccination procedures.»

An inflammatory protein that triggers a pregnant mouse's immune response to an infection or other disease appears to cause brain injury in her fetus, but not the premature birth that was long believed to be linked with such neurologic damage in both rodents and humans, new Johns Hopkins - led research suggests.

Nibbering and a team of Dutch collaborators are trying to combat these biofilm - associated infections by improving on a human peptide called LL - 37, which helps regulate the body's immune response.

«In that paper, we found a common response by the human immune system to multiple viruses that is distinct from that for bacterial infections.

The paper focuses on two key molecular players in the story of influenza infection: a human protein called TRIM25, which was recently discovered to play an important role in the human immune response to flu infection; and a protein called NS1 present in all strains of the influenza A virus and shown to bind TRIM25 to keep it from doing its job.

The UNC research team, led by Lemon and Jason Whitmire, Ph.D., Associate Professor in UNC's Department of Genetics, is now poised to investigate the complicated interplay of nonspecific «innate» and specific «adaptive» immune responses that ultimately control the infection and eliminate HAV from the host — processes that are not well understood for any of the five human hepatitis viruses.

«These data provide the basis for understanding the immune response to filovirus infections in humans,» said Bukreyev.

The researchers found that resistin, an immune protein commonly found in human serum, instigates an inappropriate inflammatory response to worm infections, impairing the clearance of the worm.

IDMIT will contribute 1) To the development and validation of assays based on flow cytometry and mass cytometry for the evaluation of immune responses in humans and animal models; these tools will be particularly relevant for the identification of signatures of vaccine efficacy; 2) To the animal model platform, in particularly by providing access to NHP models and to new technologies for in vivo imaging infections and host responses; 3) To networking activities, in particular by organising a workshop on in vivo imaginTo the development and validation of assays based on flow cytometry and mass cytometry for the evaluation of immune responses in humans and animal models; these tools will be particularly relevant for the identification of signatures of vaccine efficacy; 2) To the animal model platform, in particularly by providing access to NHP models and to new technologies for in vivo imaging infections and host responses; 3) To networking activities, in particular by organising a workshop on in vivo imaginTo the animal model platform, in particularly by providing access to NHP models and to new technologies for in vivo imaging infections and host responses; 3) To networking activities, in particular by organising a workshop on in vivo imaginto NHP models and to new technologies for in vivo imaging infections and host responses; 3) To networking activities, in particular by organising a workshop on in vivo imaginto new technologies for in vivo imaging infections and host responses; 3) To networking activities, in particular by organising a workshop on in vivo imaginTo networking activities, in particular by organising a workshop on in vivo imaging.

Dr. Anuja Mathew is the newest members of the iCubed team, joining the Institute in August 2015 to research human immune responses to dengue virus infections alongside world renowned Dr. Alan Rothman.

She is registred to the National Order of Biologists in the province of Palermo; collaboration in research project from 2012 to 2015 at the Department of Biopathology and Biotechnology, University of Palermo, focusing the study on the identification of molecules capable to modulate intracellular metabolic pathways for the prevention and treatment of infectious, tumor and degenerative disease, in collaboration with Prof. Angela Santoni, University of Rome; collaboration in research project in 2011 at the hospital «Villa Sofia Cervello» of Palermo to study methods can cure the genetic defect that causes thalassemia through genetic engineering; she studies different mechanisms of the differentiation and the activation of human gammadelta T cells as effector cells of the immune response against cancer and infectious diseases; she investigates about the identification and development of biomarkers of resistance and susceptibility to Mycobacterium tuberculosis infection; Valentina Orlando has published 13 papers in peer reviewed journals and 3 comunications at national and international congress.

He teamed with Dr. Janeway in the search for the gene in the innate immune system that activates the adaptive system — to address the questions, how does the human body know when it has an infection, and how does a microbial infection trigger an immune response?

This premature enthusiasm has more recently given way to caution as the technology has gradually been transferred to humans, with only limited short - term success.3 Finally, since HIV usually enters the body through mucosal surfaces — the vagina and rectum — augmenting an immune response at these portals of entry by using what scientists call mucosal AIDS vaccines might be an additional way to improve protection against infection.

As current therapeutics are limited, it is essential to define the immune evasion strategies of these fungal pathogens which cause life - threatening infections and at the same time to understand the immune response of the human host to these fungal pathogens.

Nippostrongylus brasiliensis, a nematode parasite of rodents, has a parasitic life cycle that is an extremely useful model for the study of human hookworm infection, particularly in regards to the induced immune response.

Using parallel methods of protection as in humans, pet vaccines initiate defensive immune response, preparing the animal's body to fight a potential future infection.

humans have landed on an asteroid to mine valuable minerals from it, however as they burrow into the ground, the sentient rock produces its own auto - immune response, much in the same way that the human body produces white - blood cells in response to an infection.