Since 2006 when Biomedcode was established, we have evaluated hundreds of therapeutics including novel biologics, biosimilars, biobetters and small molecules using a unique array of animal disease models closely mimicking the complexity of
human inflammatory conditions.
Not exact matches
Additional
human studies are needed to explore how individual differences in maternal breast milk composition could predispose to intestinal
inflammatory conditions, such as allergic disease.
A study by researchers at the University of Chicago Medicine shows that when mice that are genetically susceptible to developing
inflammatory bowel disease (IBD) were given antibiotics during late pregnancy and the early nursing period, their offspring were more likely to develop an
inflammatory condition of the colon that resembles
human IBD.
In a study that has implications for
humans with
inflammatory diseases, researchers from Case Western Reserve University School of Medicine and colleagues have found that, given over a six - week period, the artificial sweetener sucralose, known by the brand name Splenda, worsens gut inflammation in mice with Crohn's - like disease, but had no substantive effect on those without the
condition.
Using cells from mice and
human livers, Toronto General Hospital Research Institute researchers demonstrated for the first time how under specific
conditions, such as obesity, liver CD8 + T cells, white blood cells which play an important role in the control of viral infections, become highly activated and
inflammatory, reprogramming themselves into disease - driving cells.
There are strong associations between the
human gut microbiome and
conditions including obesity, type - 2 diabetes, cirrhosis, rheumatoid arthritis and
inflammatory bowel disease.
In a study that has implications for
humans with
inflammatory diseases, researchers from Case Western Reserve University School of Medicine and colleagues have found that, given over a six - week period, the artificial sweetener sucralose, known by the brand name Splenda, worsens gut inflammation in mice with Crohn's disease, but had no substantive effect on those without the
condition.
Ten U.S. patents issued or pending include Dr. Prendergast as an inventor in this important new arena of immune modulation emerging as pivotal in
human cancer, autoimmunity, chronic viral infection and other chronic
inflammatory conditions.
Dr. Goleva concluded «The fact that we showed a dose - dependent and varying response to levels commonly found in
humans also adds weight to the argument for vitamin D's role in immune and
inflammatory conditions.»
Found in legumes, fruits, vegetables, herbs and wine, recent published
human clinical research has demonstrated the ability of FruiteX - BTM to modulate key markers of inflammation and improve elevated serum levels of CRP, a diagnostic marker associated with
inflammatory conditions.
An earlier study found similar results, showing that a deficiency in EFAs leads to
inflammatory skin
conditions in both animals and
humans.