Sentences with phrase «human intervention trials»

If you're not eating wild - caught fish three or four times a week, human intervention trials show supplementing with omega - 3s can also help reduce visceral fat.

Not exact matches

Katherine High, Spark's president and chief scientific officer, expressed her enthusiasm for the early clinical data related to SPK - 8011: «The encouraging start of our SPK - 8011 clinical trial reinforces the strength of our gene therapy platform, delivers human proof - of - concept in a second liver - mediated disease — a significant achievement in the gene therapy field — and positions us well to potentially transform the current treatment approach for this life - altering disease with a one - time intervention
«Computational models like this one might one day be able to predict the clinical course of a disease or injury, as well as make it possible to do less expensive testing of experimental drugs and interventions to see whether they are worth pursuing with human trials,» he said.
«And now we have literally dozens and dozens of randomized controlled trials across a range of conditions in low - resource settings using low - cost human resources,» he says, «and they're backed by economic data of the cost effectiveness of these interventions
«However, while these encouraging results in mice mean that the zinc finger looks like a good candidate to take forward to human trials, we still need to do a lot of work first to answer important questions around the safety of the intervention, whether repeat treatments are effective, whether there might be longer - term side effects, and whether we can extend and increase the benefits beyond six months.
«The goal is to identify the precise circuits that would be most amenable to interventions in the human brain, post-stroke, so that we can take this approach into clinical trials
Many interventions now or soon to be in human trials seek to mimic those effects.
NIH Clinical Center (CC)-- Est. in 1953 The NIH Clinical Center, America's research hospital, provides a versatile clinical research environment enabling the NIH mission to improve human health by investigating the pathogenesis of disease; conducting first - in - human clinical trials with an emphasis on rare diseases and diseases of high public health impact; developing state - of - the - art diagnostic, preventive, and therapeutic interventions; training the current and next generations of clinical researchers; and, ensuring that clinical research is ethical, efficient, and of high scientific quality.
In a substudy, review outcomes were also compared across different types of clinical research, based in large part on the designations and definitions derived from a number of sources, including a report by Nathan, 14 the Institute of Medicine, 20 the NIH Director's Panel on Clinical Research, 9 the Association of American Medical Colleges and American Medical Association, 21 and the Agency for Healthcare Research and Quality.22 All 3599 R01 applications involving human subjects that were submitted to NIH for the October 2002 council were categorized into 1 of the following: (1) patient - oriented studies of mechanisms of human disease (bench to bedside); (2) clinical trials and other clinical interventions; (3) patient - oriented research focusing on development of new technologies; (4) epidemiological studies; (5) behavioral studies (including studies of normal human behavior); (6) health services research; and (7) use of deidentified human tissue.
Whereas the few randomized controlled trials and observational clinical outcomes studies support the existence of a health benefit from fasting, substantial further research in humans is needed before the use of fasting as a health intervention can be recommended.
Ellagic acid metabolism by human gut microbiota: consistent observation of three urolithin phenotypes in intervention trials, independent of food source, age, and health status.
But a 2006 study for the National Institutes of Health Glucosamine / Chondroitin Arthritis Intervention Trial concluded that the supplements weren't effective in humans with mild pain.
While the review of the policies and programs undertaken in the NT intervention has just commenced, the Social Justice Report 2007 expresses preliminary concerns with the income management trials in, in terms of the compliance with human rights standards.
Background This randomized clinical trial compared 16 - week interventions with interpersonal psychotherapy, cognitive behavioral therapy, supportive psychotherapy, and supportive psychotherapy with imipramine for human immunodeficiency virus (HIV)- positive patients with depressive symptoms.
This randomized clinical trial compared 16 - week interventions with interpersonal psychotherapy, cognitive behavioral therapy, supportive psychotherapy, and supportive psychotherapy with imipramine for human immunodeficiency virus (HIV)- positive patients with depressive symptoms.
She is also a co-investigator on a randomized efficacy trial of a school readiness intervention program with foster children and a multisite Center investigating the behavioral and neurobiological impacts of early adverse experiences in humans and nonhuman primates.
a b c d e f g h i j k l m n o p q r s t u v w x y z