«Mouse and
human kidney development compared: Findings may lead to advances in the study and treatment of kidney disease.»
The data bring an understanding of
human kidney development to a new level,» said Dr. McMahon.
«We analyzed
human kidney development, identifying features that distinguish our kidney from its well - studied mouse counterpart.
Researchers modeled kidney development and injury in kidney organoids (shown here), demonstrating that the organoid culture system can be used to study mechanisms of
human kidney development and toxicity.
Not exact matches
Breastfeeding improves vision and oral
development; breastfed babies have fewer ear infections; breast milk is better for the cardiovascular system and
kidneys; and babies» intestinal immunity is enhanced by
human milk.
The Golden Goose Award has honored innovative research that developed a diabetes medication from Gila monster venom, an algorithm based on marriage stability that led to the
development of a program to match
kidney patients with donors and the «marshmallow test» — a measure of young children's self - control that has led to greater understanding of
human behavior.
Lin28 is closely tied to organ and tissue
development in organisms as diverse as worms and
humans, and is active in the
kidneys early in
development.
Research in the laboratory of Rebecca Wingert, the Gallagher Family Associate Professor of Adult Stem Cell Research in the Department of Biological Sciences at the University of Notre Dame, has confirmed the key role of a certain small molecule in the
development of
kidney structures in zebrafish, a widely used model for
human kidneys.
A search of the CRISP database of NIH - funded research projects on three key words — mutant, androgen, and receptor — yields 24 projects funded since 1999 by nine different NIH institutes: the National Cancer Institute (eight projects), the National Institute of General Medical Sciences (NIGMS, three projects), the National Institute of Child Health and
Human Development (three projects), the National Institute of Diabetes and Digestive and
Kidney Diseases (two projects), and the National Center for Research Resources (two projects).
Among the other NIH institutes that currently fund Monell's biomedical research are the National Institute of Diabetes and Digestive and
Kidney Diseases, the National Institute on Alcohol Abuse and Alcoholism, and the Eunice Kennedy Shriver National Institute of Child Health and
Human Development.
The 19 NIH institutes, centers and offices contributing to the Knockout Mouse Project are: the NIH Office of Strategic Coordination / Common Fund; NCRR; the National Eye Institute; NHGRI; the National Institute of Allergy and Infectious Diseases; the National Heart, Lung and Blood Institute; the National Institute on Aging; the National Institute of Alcohol Abuse and Alcoholism; the National Institute of Arthritis and Musculoskeletal and Skin Diseases; the Eunice Kennedy Shriver National Institute of Child Health and
Human Development; NIDCD; the National Institute of Dental and Craniofacial Research; the National Institute of Environmental Health Sciences; the National Institute of General Medical Sciences; the National Institute of Mental Health; the National Institute of Neurological Disorders and Stroke; the National Institute of Diabetes and Digestive and
Kidney Diseases; the National Cancer Institute; and the Office of AIDS Research.
ViaCyte, Inc. (CA, USA) has received a Small Business Innovative Research Phase III award from the National Institute of Diabetes and Digestive and
Kidney Diseases (NIDDK; MD, USA) to further the
development of stem cell - derived functional
human beta cells in vitro.
Human embryonic stem cells grown at the University of Wisconsin - Madison randomly changed into cell types found in the A) gut B) brain C) bone marrow D) cartilage E) muscle F)
kidney Scientists haven't learned to control the
development.
«The
development of a functional
human kidney glomerulus chip opens up an entirely new experimental path to investigate
kidney biology, carry out highly personalized modeling of
kidney diseases and drug toxicities, and the stem cell - derived
kidney podocytes we developed could even offer a new injectable cell therapy approach for regenerative medicine in patients with life - threatening glomerulopathies in the future,» said Ingber.
In line with these data we demonstrate that combined deletion of Vhl and Pbrm1 in the mouse
kidney is sufficient for the
development of fully - penetrant, multifocal carcinomas, closely mimicking
human ccRCC.
A combination of limited
human data and a wealth of animal studies show that phthalates, as only one of many chemicals in fragrances, can impair reproduction and
development, alter liver and
kidney function, damage the heart and lungs, and effect blood clotting.
The use of colloids is highly controversial in
human medicine and becoming so in veterinary medicine as well, 12 with recent research13 implicating a link between the use of a synthetic colloid and the
development of acute
kidney injury in dogs.
Research in
humans shows that untreated periodontal disease is a key factor in the
development of heart, liver and
kidney problems and is a source of chronic low - grade infection.
Ethoxyquin has been forbidden from use in
human products because it has been linked with the
development of
kidney and liver disease, cancer (liver, spleen, stomach, and skin), immune deficiency syndrome, blindness, and leukemia.