Sentences with phrase «human kidney glomeruli»

This achievement shows that human kidney glomeruli made in vitro can connect to blood vessels after transplantation and grow to maturity.

Now, with the team's newly engineered human kidney glomerulus - on - a-chip, researchers also can get in vitro access to the kidney's core filtration mechanisms that are critical for drug clearance and pharmacokinetics, in addition to studying human podocytes at work.

«The development of a functional human kidney glomerulus chip opens up an entirely new experimental path to investigate kidney biology, carry out highly personalized modeling of kidney diseases and drug toxicities, and the stem cell - derived kidney podocytes we developed could even offer a new injectable cell therapy approach for regenerative medicine in patients with life - threatening glomerulopathies in the future,» said Ingber.

Not exact matches

After transplanting the human iPS cell - based kidney tissue into a mouse body, glomeruli connecting to mouse kidney capillaries formed.

sFlt1 caused swollen glomeruli (right)-- a known symptom of human preeclampsia — in pregnant rats» kidneys.

In 2013, his team developed an organ - on - a-chip microfluidic culture device that modeled the human kidney's proximal tubule, which is anatomically connected to the glomerulus and salvages ions from urinary fluid.

A glomerulus - on - a-chip lined by human stem cell - derived kidney cells could help model patient - specific kidney diseases and guide therapeutic discovery