They found out that TiY is capable of distinguishing TICs from non-TICs in various
human lung cancer cell lines and patient - derived lung tumors.
By using molecular genetic tools to reduce the amount of PC
in human lung cancer cells, the team observed decreased cell growth, a compromised ability to form colonies in soft agar (a gelatinous material specifically used to grow bacteria and other cells), and a reduced rate of tumor growth in mice.
In this study,
human lung cancer cells with additional copies of the opioid receptor grew more than twice as fast as tumor cells that lacked extra receptors when transplanted into mice.
One study presented in the journal — from a group led by Patrick Singleton, PhD, assistant professor of medicine at the University of Chicago Medicine — shows how opioids already present in the body can enhance the malignant tendencies of
human lung cancer cells transplanted into mice, even without the addition of morphine.
Using both fruit fly and
human lung cancer cell lines, researchers targeted two of the most common genetic mutations associated with NSCLC — Ras and PTEN (P13K).
I wanted to inactivate the gene BRAF (a kinase implicated in several human cancers) in A549 cells (
a human lung cancer cell line), armed only with viruses obtained through Addgene's viral service and the methods sections of scientific articles (gasp).
(a kinase implicated in several human cancers) in A549 cells (
a human lung cancer cell line), armed only with viruses obtained through Addgene's viral service and the methods sections of scientific articles (gasp).
Title of thesis: «Study of the pro-apoptotic effect of histones deacetylases inhibitors, used alone and concurrently with chemotherapeutic agents, on
human lung cancer cells».